1.Effects of Cluster Needling of Scalp Acupuncture Combined with Rehabilitation on Learning and Memory Ability and Expression of Synaptophysin in Rats with Hippocampal Infarction
Chinese Journal of Rehabilitation Theory and Practice 2012;18(2):101-103
Objective To explore the effects of cluster needling of scalp acupuncture combined with rehabilitation on learning and memory ability and expression of synaptophysin in rats with hippocampal infarction. Methods 50 rats were randomly divided into sham operation group, model group, acupuncture group, rehabilitation group and acupuncture with rehabilitation group, 10 rats in each group. Photochemical method was used to induce hippocampal infarction model. 24 h after modeling, they were intervened respectively. Y-type maze was used to evaluate the learning and memory ability and immunohistochemistry method was used to observe the expression of synaptophysin after 14 d intervention. Results Compared with the sham operation group, the learning and memory ability in the other groups declined,and the expression of synaptophysin increased (P<0.05). Compared with the model group, both the learning and memory ability and the expression of synaptophysin increased in the acupuncture group, the rehabilitation group and the acupuncture with rehabilitation group (P<0.05). The acupuncture with rehabilitation group was better than the acupuncture group and the rehabilitation group (P<0.05). Conclusion The cluster needling of scalp acupuncture combined with rehabilitation can promote the learning and memory ability and the expression of synaptophysin in rats.
2.Network Meta-analysis of the effects of different types of exercises on children with attention deficit hyperactivity disorder
Lingrong XIAO ; Hongmei WU ; Gang ZHAO ; Yisi JIN ; Xiaoxue WU ; Siyan LIU ; Junru LI
Chinese Journal of Behavioral Medicine and Brain Science 2024;33(8):727-735
Objective:To evaluate the effects of different exercises on executive function, moter skills and core symptoms in children with attention deficit hyperactivity disorder (ADHD) using network Meta-analysis, and to provide evidence-based basis for the treatment of children with ADHD.Methods:The randomized controlled trails(RCTs)of exercises on children with ADHD were searched in Web of Science, PubMed, Cochrane Library, Embase, PsycINFO, CNKI, Wanfang Data, VIP and CBM databases.The retrieval time limit was from the establishment of each database to May 2023.The Cochrane quality review manual was used to evaluate the quality of the included literatures.Stata 17.0 software was used to perform network Meta-analysis.Results:Finally, twenty-four studies were enrolled including five types of exercise intervention, such as aerobic exercise, multicomponent exercise, exergaming, high intensity interval training (HIIT) and traditional low-to-moderate intensity exercise therapy (TRAD).The results of network Meta-analysis showed that: in terms of improving executive function(working memory, inhibitory control, and cognitive flexibility), motor skills and core symptoms of children with ADHD, the optimal exercise intervention was aerobic exercises (surface under the cumulative ranking were 78.9%, 73.0%, 88.7%, 77.9% and 69.9% respectively).Conclusion:Exercises can improve executive function, improve motor skills, and alleviate ADHD core symptoms.Aerobic exercise has a better effect on improving executive function, motor skills and core symptoms of ADHD children.