Objective To search for one method which is security firm and effective for trachea intubation in order to avoid unplanned extubation and realize nursing security. Methods 120 cases with severe brain injury and trachea intubation were divided into the observation group and the control group with 60 cases in each group randomly.The trachea intubations was fixed with Y-type plaster in the observation group,the control group used traditional fixation method with two pieces of 3M transparence film.The cases with trachea cannula displacement and unplanned extubation were compared between two groups. Results The cases needed re-fixation of the trachea cannula and with unplanned extubation in the observation group was less than the control group. Conclusions To use Y-type plaster to fix the trachea intubation can effectively prevent unplanned extubation,increase efficiency of clinical nursing work and ensure the security of patients.