Objective To explore the differential diagnostic value of color-Doppler technique in acute and chronic thrombosis of leg arteries. Methods The two-dimensional and color Doppler ultrasonographic characteristics were analyzed in acute thrombostic event in 80 leg arteries and chronic thrombostic events in 244 leg arteries. And some parameters (history, the vessel wall structures, hemodynamic of inlet and outlet at the lesion) were compared, too. Results There existed a significant difference in history, vessel wall structure and the establishment of collaterals between the acute and chronic groups. And there were also significant difference in maximum blood velocity proximal and distal to the lesion and proximal resistant index between two groups(P

Post-inflammatory hyperpigmentation is a common sequela of acne, its pathogenesis is complex, its physiological mechanism is not fully understood at present. A variety of cell types, cytokines and growth factors are involved in its pathogenesis. It is not only difficult to improve and lasts a long time, which has a great impact on patients’ psychology and life. In this paper, molecular mechanism of post-inflammatory pigmentation, experimental models in vitro and in vivo, and extracts of Chinese medicine regulating related pathways were reviewed, in order to provide references for safe and effective application of Chinese medicine extracts to improve post-inflammatory hyperpigmentation in patients.