1.Differential diagnostic process of aphasia types in Chinese aphasia (I)
Chinese Journal of Rehabilitation Theory and Practice 1997;3(1):10-12
本文介绍了北医大汉语失语成套测验(ABC)。根据10年失语症研究的经验总结出汉语失语症的主要类型及其鉴别论断要点,并根据复述、流利性、听理解及口头还是书面语言障碍这4个要素总结出鉴别各型汉语失语症的鉴别诊断流程图。指出失语症分型可为语言康复提供可靠依据,4个鉴别要素尚可提供大脑病灶定位信息。
3.The Differential Diagnosis Flow Diagram of Aphasia Types in Chinese Aphasia
Chinese Journal of Rehabilitation Theory and Practice 1997;3(2):57-59
It was introduced that the Aphasia Battery of Chinese (ABC), proposed by neurology department of Beijing Medical University. According to the experience of aphasia research for 1O years, we summarized the main types of Chinese aphasia and the differential diagnostic principles for them,and the differential diagnosis flow diagram of all major Chinese aphasia types was advanced according to the four principles-Ai repetition, fluency, auditory comprehension and oral or written language disorders. It was pointed out the classification of aphasia will provide the reliable basis for language rehabilitation and the four principles offer the information for localized lesions of brain.
5.OBSERVATION OF MICROCIRCULATION IN DIABETIC PATIENTS WITH CEREBRAL
Chinese Journal of Endocrinology and Metabolism 1985;0(02):-
Twenty-three diabetic patients with cerebral-thrombosis (DCT) and 16 cases without (D), 67 cases of nondiabetic cerebral thrombosis (CT), and 50 healthy subjects were investigated on the microcirculation of nailbed and conjunctiva with Model WX-7.53 microcirculation microscope. The results showed that all the patients had micro circulatory abnormality of nailbed, and,conjunctiva. The severity of microcirculatory abnormality was significantly different between these three groups of patients (P
7.Lexical decision reaction time study of reading Chinese in patients with mild Alzheimer’s disease and mild cognitive impairment
Chinese Journal of Neurology 2005;0(08):-
Objective To delineate the changes in pattern and time course of semantic and phonological processing during Chinese language cognition study in patients with mild Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Methods Patients with mild AD(n=32)and MCI (n=39) as well as normal controls (NC, n=40) matched with age, gender, level of education were enrolled in the study. Subjects completed Chinese compound word decision task applying both short and long stimulus onset asynchrony (SOA). Semantic, homophonic, semihomophonic and unrelated primes preceded the real words as well as nonwords targets. Subjects were asked to judge whether the targets were real words or nonwords. The reaction time and accuracy were recorded for each response. Semantic and phonological priming effects were analyzed by comparing the related primes versus unrelated primes. Analyses of variance (ANOVA) and t-test were conducted for reaction time and accuracy respectively. Results The mean reaction times of mild AD and MCI groups were prolonged (411 ms and 234 ms) for all types of priming in contrast with NC(P
8.Study on the auditory comprehension impairments of Chinese aphasics in cerebrovascular diseases
Chinese Journal of Rehabilitation Theory and Practice 2001;7(1):4-6
ObjectiveImpairment in auditory comprehension is one of the most common clinical symptoms of aphasia. Analysing the features of Chinese aphasics in auditory comprehension might be valueable to classify the types of aphasia, distinguish the difference between the Western aphasics and Chinese aphasics, and find out the neural mechanisms in the language processes in the brain. MethodsThe Standardized Aphasia Battery in Chinese and Additional Test of Auditory Comprehension were utilized, and the cerebral lesion of each case was demonstrated by CT scan or MRI. Results and Conclusions 1.Different types of aphasia indicate different damage grades in auditory comprehension impairment at each stage. 2. Posterior apasia and mixed aphasia indicate damages in the phonemic discrimination abilities. There are phonemic discrimination abilities preserved in Anterior aphasia and subcortical aphasia. 3. Anterior aphasia, posterior aphasia and mixed aphasia are at a different difficulty grades for lexical comprehension, especially for the discrimination to body parts. Subcortical aphasia doesn\'t demonstrate this feature that might be the characteristic in Chinese aphasics different from English aphasics. 4. The comprehension of the passive sentences is more difficult than that of the active sentences for all types of aphasics . 5. The damages are all severe in the story comprehension for all types of aphasics.
9.Neuropsychological Study of Agnosia in Patients with Cerebral Vascular Disease
Chinese Journal of Rehabilitation Theory and Practice 1999;5(1):17-19
In order to study the type and cerebral location of agnosia in patients with cerebral vascular disease, 35 patients with single cerebral lesion determined by CT or MRI were checked. The standardized Aphasia Battery in Chinese and self designed tasks about agnosia were adopted. The results showed that there were object agnosia, picture agnosia, color agnosia, agnosia acalculia, auditory agnosia, tactile agnosia, neglect, environmental agnosia, body agnosia in left hemisphere group, and color agnosia, neglect, environmental agnosia, anosognosia in right group. The conclusions were that for the majority of dextrals, cerebral dominance for visual, auditory, tactile, body cognition all located in the left hemisphere. Color agnosia may happen in right hemisphere. Either hemisphere can produce neglect, anosognosia, and the incidence in right hemisphere is higher than in left one.