1.Clinical observation on humid-heat type of rheumatoid arthritis treating by TCM
Xiaoli ZHOU ; Yingxu WANG ; Liping HOU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(12):-
Objective:To evaluate the effect of fire needle with regulating respiration by mu point treatment and regulating zang by shu point treatment on humid-heat type of rheumatoid arthritis(RA).Methods:120 patients with RA were randomly divided into two groups:the treatment group received fire needle with regulating respiration by mu point treatment and regulating zang by shu point treatment,the control group were administrated with Dichronic tablets.The changes of rheumatoid factor(RF),erythrocyte sedimentation rate(ESR),C reactive protein(CRP),immune globulin and the indexes of swelling,aching,morning stiffness of joints were observed.Results:After treatment,the curative effect rate in the treatment group was higher than that in the control group(P
2.Laparoscopic left liver resection to treat intrahepatic lithiasis
Tianxi LIU ; Denghua FANG ; Haolei YANG ; Binying GUAN ; Yingxu LI ; Xingru WANG
Chinese Journal of Hepatobiliary Surgery 2012;18(8):605-607
Objective To study the feasibility and efficacy of intraoperative choledoscopy combined with laparoscopic left liver resection to treat intrahepatic lithiasis.Method In 49 patients with biliary stone,laparoscopic left lateral sectionectomy/left medial sectionectomy/left hepatectomy combined with intraoperative choledochoscopy and stone retrieval were carried out.Results Laparoscopic left lateral sectionectomy was carried out in 29 patients,left medial sectionectomy in 2 patients and left hepatectomy in 18 patients.In all the patients,combined choledoscopy and stone retrieval were carried out.A concomitant laparoscopic cholecystectomy (LC) was carried out in 11 patients.The average operative time was 226 min.When LC was carried out,the mean operative time was 243 min.The mean intraoperative blood loss was 378 ml.There was no bile leak or postoperative bleeding.Flatus was passed 1-3 days after surgery.The patients were discharged home 7-10 days after surgery.Postoperative MRI/MRCP did not reveal any residual stone.On a mean follow up of 16 months for 47 patients,the patients did well and there was no recurrent stone.Conclusion Choledochoscopy combined with laparoscopic left liver resection for bile duct stone resulted in minimal trauma to the patient.The recovery was quick and there was a high stone clearance rate.The treatment was safe,efficacious,and it is a viable minimally invasive treatment option.
3.Correlation between BMI and metagenomics concentration of gut microbiota of college students in Inner Mongolia
XU Xinrui,WANG Xinyu,ZHANG Jing,GENG Yikun,BIAN Haodong,WU Yingxu,LIU Yanchao
Chinese Journal of School Health 2021;42(1):106-108
Objective:
To explore the correlation between BMI and gut microbiota of college students in Inner Mongolia,and to provide a reference basis for revealing the relationship between intestinal flora and obesity.
Methods:
Totally 88 college students from Inner Mongolia Medical University were enrolled, Height and weight were measured,and the feces samples were collected. The bacterial metagenome was extracted from dry feces samples for the concentration detection in per gram of dry feces,expressed as μg/μL. Correlation between BMI and metagenomics concentration of gut microbiota was statistically analyzed. Meanwhile,the metagenomics concentration of gut microbiota in different BMI groups was compared with each other.
Results:
There was a negative correlation between BMI and the metagenomics concentration of gut microbiota(r=-0.27,P<0.05). Significant difference in the concentration of gut microflora was observed between the normal group and the obesity group,the normal group and the overweight/obesity group(F=3.62,P<0.05). Among the female volunteers,there were significant differences between normal group and overweight group,between normal group and obesity group(F=1.87,P<0.05). No significant differences in metagenomics concentration of gut microbiota were found in different BMI groups(F=0.60, P>0.05).
Conclusion
There is a correlation between BMI and gut microbiota of college students in Inner Mongolia,the concentration of gut microflora metagenome in overweight and obese people decreased significantly.
4.Mediating effect of insomnia in the relationship between childhood trauma and suicide risk in middle school students
Wenzhi HE ; Jian WEN ; Yao WANG ; Junlin WU ; Shuwen WEN ; Hudan CHEN ; Junlin QIU ; Yingxu SONG ; Lijun LIANG ; Guoping HUANG
Chinese Journal of Behavioral Medicine and Brain Science 2022;31(4):359-365
Objective:To explore the mediating role of insomnia between childhood trauma and suicide risk in middle school students.Methods:Childhood trauma questionnaire(CTQ), insomnia severity index(ISI) and suicidal behaviors questionnaire-revised(SBQ-R) were used to investigate 3 442 middle school students.According to the total score of the SBQ-R, those who scored less than or equal to 6 were divided into low suicide risk group, and those who scored more than or equal to 7 were divided into high suicide risk group.In this study, there were 2 168 students in the low suicide risk group and 1 274 students in the high suicide risk group.SPSSAU 21.0 online statistical software was used for common method deviation test, descriptive statistics, variance analysis and correlation analysis, and structural equation model was constructed, and Bootstrap method was used for mediation effect test.Results:(1) There were statistically significant differences between the high suicide risk group and the low suicide risk group in terms of grade and gender( χ2=11.144, 83.737, both P<0.05), and there were statistically significant differences in the types of childhood trauma and the severity of insomnia( χ2=292.211, 333.998, both P<0.05). (2) The total score of childhood trauma in the high suicide risk group (43.92±10.50) was higher than that in the low suicide risk group (37.74±6.93) ( F=351.78, P<0.01), and the score of insomnia in the high suicide risk group (10.66±5.54) was higher than that in the low suicide risk group (7.04±4.76) ( F=379.25, P<0.01). (3)The total score of childhood trauma was positively correlated with the score of suicide risk ( r=0.415, P<0.01), and the total score of childhood trauma was positively correlated with the score of insomnia ( r=0.306, P<0.01), and the score of insomnia was significantly positively correlated with the score of suicide risk ( r=0.399, P<0.01). After controlling for demographic data, anxiety and depression, the correlation was still significant ( P<0.01). (4) Path analysis and mediation test showed that childhood trauma had a positive effect on insomnia ( β=0.30, P<0.01), insomnia had a positive effect on suicide risk ( β=0.29, P<0.01), and childhood trauma had a positive effect on suicide risk ( β=0.33, P<0.01). The mediating effect of insomnia accounted for 21.21% of the total effect.After controlling for demographic data, anxiety and depression, the mediating effect accounted for 10.66% of the total effect. Conclusion:Childhood trauma and insomnia have a significant impact on the suicide risk among middle school students.Insomnia plays a partial mediating role between childhood trauma and middle school students' suicide risk.Timely management of the sleep disturbances of traumatized individuals can reduce the suicide risk among middle school students.