1.Review of diagnosis and treatmem of eye wounds in subtropical mountains and bush zone
Meixiang GENG ; Yi YIN ; Changuang XU ; Junyin ZHAI ; Yingqiong FENG ; Guifang WANG
Chinese Journal of Trauma 2009;25(8):757-761
Objective To study the features of eye wounds in subtropical mountain and bush zone so as to improve success rate of medical therapy and decrease disability rate for eye wounds. Methods The clinical data of eye wounds caused by Selfdefense War against Vietnam from No. 59 Hos-pital of PLA were analyzed. Results Monocular injuries accounted for 81.7% of eye wounds, with no statistical difference in the injuries between left eye and right eye. Eye wounds caused by shrapnel ac-counted for 82.2%, and it was the main injury factor. The rate of eye injuries complicated with other in-juries of the body was up to 75.6%. Globe wounds were the most commonly seen, with open globe wound accounting for 45.1%. Conclusion Timely and correct ophthalmological treatment can effectively re-duce the blinding rate.
2.A clinical study of chromosome translocations in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in Chinese patients
Gehong DONG ; Guiqiu WANG ; Liping GONG ; Jinfen WANG ; Xianglan MO ; Honggang LIU ; Lina DONG ; Yingqiong ZHOU ; Xuemei ZHANG ; Zhenbo FENG ; Zifen GAO ; Hongtao YE
Chinese Journal of Internal Medicine 2009;48(3):181-185
Objective To investigate the genetic aberrations in extranodal marginal zone lymphoma of mueosa-associated lymphoid tissue (MALT) lymphomas from different sites of the body in Chinese patients. Methods Two hundred and seventeen paraffin-embedded MALT lymphoma specimens from 11 major sites were studied with interphase fluorescence in situ hybridization (FISH) to detect t(11; 18) (q21;q21)/API2-MALT1, t(1; 14) (p22; q32)/IGH-BCL10, (14; 18) (q32; q21)/IGH-MALT1 and BCL6 gene involved chromosome translocations. Results These translocations were mutually exclusive and detected in 21% (46/217) of the cases, including t(11;18) (q21;q21) API2-MALT1 13% (29/217), t (1;14)(p22 ;q32) IGH-BCLIO in 1% (3/217), t(14;18) (q32;q21) IGH-MALT1 1% (2/217), BCL6 involved translocation in 2% (4/217) and IGH-unknown translocation partner in 4% (8/217). t(11; 18) (q21;q21)API2-MALT1 was found with the highest frequency in MALT lymphoma from lungs (47% , 8/17) and small intestine (29%, 4/14), followed by salivary gland (17%, 1/6), stomach (14%, 12/84) and ocular adnexae (6% , 4/68). t(1 ;14) (p22;q32) was only detected in lungs (12%, 2/17) and stomach (1%, 1/84). t(14;18) (q32;q21) was mainly detected in lungs (6%, 1/17) and ocular adnexae (2%, 1/68). BCL6 gene involved translocation was detected in salivary gland (17% , 1/6) and stomach (4%, 3/84). Conclusions It is demonstrated that the four translocatidns occur with markedly variable frequencies in MALT lymphoma of different sites in Chinese patients. The distributions of these chromosome translocations in Chinese patients are slightly different from those reported in western patients.