Cancer-testis antigens (CTAs) are protein antigens with normal expression restricted to adult testis and yet are aberrantly activated and expressed in a proportion of various types of tumor tissues. The expressions of CTA correlate with tumor staging, histopathological subtype, recurrence and metastasis in nonsmall cell lung cancer. CTAs are immunogenic in lung cancer patients and have a good prospect in lung cancer Immunotherapy.

Objective To explore the correlation between nurses' job burnout and social support and the source of job stress. Methods 138 doctors and 162 nurses from 4 general hospitals were investigated by different questionnaires. The nurses were investigated by Maslach Burnout Inventory(MBI),perceived social support scale(PSSS)and Chinese nurse job stress source scale. While the doctors only underwent investigation using Maslach Burnout Inventory (MBI).The results were collected and analyzed. Results The MBI results showed that the scores of emotional exhaustion and non-humanity were apparently higher, while the score of sense of working achievement was lower in nurses than those in doctors. The level of job burnout in nurses was higher than that of doctors with statistical difference. The score of social support was lower and the score of source of job stress was higher in nurses with increased level of job burnout than those with decreased level. Conclusion The status of nurses' job burnout should cause the attention of nursing managers. Prompt and selective measures should be adopted to improve the psychological health of nurses.

Objective To investigate the influence of social support on work-family conflict and psychological control ability of nurses. Methods 126 women nurses from four general hospitals by the method of random cluster sampling were divided into two groups according to the scores of the social sup-port scale(SSRS). Nurses with score lower than 35 were set as low social support group(totally 38 nurses), nurses with score higher than 45 were named as high social support group(46 nurses).The two groups were assessed by SSRS, work-family conflict scale (WFCS) and IPC respectively. The results underwent stati-s-tical analysis with t test, χ2 test and Pearson correlation analysis. Results The age and nurses' work-ing age in high social support group were significantly higher than that of the low social support group, the to-tal score of WFCS,the time,pressure and behavior score of subscales in high social support group were sig-nificanfly lower than that of the low social support group. The internality was higher, while the power-ful others and chance were lower in high social support group than those of low social support group. SSRS was negatively correlated with all factors of WFCS, positively correlated with internality factor of IPC, neg-atively correlated with powerful others and chance factors of IPC. Conclusions The nurses with high SSRS have low work-family conflict score and strong psychological control ability, so we should strengthen the social support of nurses.

Objective To explore the application value of color Doppler ultrasound in diagnosis of intrahepatic artery aneu-rysms.Methods Thirty-six cases of intrahepatic artery aneurysm was diagnosed by color Doppler ultrasound.And the data were analyzed retrospectively.Results In the 36 cases of hepatic artery aneurysm,1 7 cases were located in the left lobe of liver,13 cases were located in the right lobe of liver,and 6 cases were located in the left and right hepatic lobe.A total of 27 cases were solitary, 6 cases were 2 aneurysm,and 3 cases were 3 and above aneurysm.Maximum was 28 mm×27 mm,and minimum was 8 mm×7 mm. There are 3 cases with mural thrombus.Liver oval cystic echo free zone was found by two-dimensional ultrasonography.The bound-ary was clear.The wall was smooth and thin.The rear echo was strengthened.The pulsatile red,blue single color flow signal(n=1 5)or vortex like red and blue color flow signal(n=21)were showed by color Doppler ultrasonography.The hepatic artery blood flow velocity spectrum was 12-29 cm/s,and resistance index was 0.60-0.68.Conclusion Color Doppler ultrasonography was the preferred imaging methodology of early screening and diagnosis of intrahepatic artery.

To observe the patients with type 2 diabetes who were injected premixed insulin analogues after short time continuous subcutaneous insulin infusion( CSII ) treatment.It was found that the patients needed premixed insulin analogue injection 2 times daily when the dosage of CSII was less than 45 U/d,and 3 times daily when the dosage was greater than 45 U/d.The relationship of dosages between premixed insulin analogue treatment ( Y ) and CSII treatment(X) was calculated by following equations:2 times daily premixed insulin analogue treatment:Y =13.093 +0.395X,3 times daily premixed insulin analogue treatment:Y =23.114+0.405X.

Arrhythmias in children with congenital heart disease may be associated either with the underlying abnormality or result from surgical intervention.The treatment rationale bases on the rapid and accurate diagnosis.As a general rule,risk-benefit analysis of drug therapy should be considered when facing an arrhythmia in a child,due to the negative inotropy.In the last decades,non-pharmacological therapy is progressively used in pediatric population.

Chylous Ascites ; congenital ; therapy ; Humans ; Infant ; Male ; Parenteral Nutrition, Total ; Somatostatin ; therapeutic use

The characteristics of knowledge exchange in medical field of China were analyzed by social network analysis with the medical data covered in CNKI Citation Database as its study object, which showed that both the inflow and outflow volumes of clinical medicine are the largest and form the core in knowledge exchange network, preclinical medicine is the theoretical base of other medical subjects and the important knowledge source in medical networks, the interchange is close between traditional Chinese medicine, surgery and other clinical subjects, oncology is rather active in interdisciplinary studies, the interchange between stomatology and psychology is rather rare with other clinical subjects in knowledge networks and stomatology and psychology are two independent subjects.Carrying out information push service for these subjects by making use of their characteristics can improve the targeted information service, step up the knowledge exchange between different medical subjects, and promote the cooperative interdis-ciplinary studies.

Niclosamide is the most commonly used molluscicide. Along with a lot of application of niclosamide more and more scientists studied its toxic effects to aquatic organisms as well as the related cell toxicity mechanism. This paper summariz?es the toxicity on cell organelle enzyme cell signaling pathway and genetic material caused by niclosamide and puts for?ward the future research direction.