ATP-tumor chemosensitivity assay(ATP-TCA)is a tumor chemosensitivity assay in vitro.Beacause of the special merites of A11P-TCA,it is seemed to be the most promising and effective method of tumor chemosensitivity in vitro.Application of ATP-TCA in clinic has got significant effects.ATP-TCA is a good method for individualized chemotherapy.

Under the environment of network,the service mode of subject librarian becomes an important strategy of intelligence serves in university libraries.To provide reference for other librarians,this paper summarizes services provided for the academic researchers by using Web of Knowledge platform resources.

Objective To study the effect of binocular vision function training for fusion in the eye position and three levels of eye function in adult patients after concomitant strabismus surgery. Methods 56 cases with postoperative concomitant strabismus were randomly divided into training group and control group . In the training group, patients were trained with software to enhance the fusion. After training for 7, 30, 180 and 365 days, the eye position, the fusion and the stereoesthesia were observed and analyzed. Results After training for 365 days, the deteriorative ratio in the training group is 3%, which is significantly lower than control group (23%)(P<0.05). The correction ratio in eye position is 20%, which is significantly higher than control group (4%)(P<0.05). The recovery ratio in binocular vision function is 53%, which is significantly higher than control group (15%)(P<0.05). The recovery ratio in stereaeuity is 46%, which is significantly higher than control group (11%)(P<0.05). Conclusions Fusion training can enhance the recovery of fusion and stereaeuity, decrease the deteriorative ratio, and correct the eye position after surgery in concomitant strabismus patients.

Objective To investigate the relationship between renal function and lipid metabolism in patients with chronic renal disease .Methods A total of 76 patients with chronic renal disease were enrolled and classified into chronic renal failure(CRF)group (29 cases) ,chronic nephritis(CN)group(21 cases) ,diabetic nephropathy (DN) group(14 cases) and nephrotic syndrome (NS) group (12 cases) ,and 65 healthy subjects were enrolled in control group ,the relationships between renal function ,lipid metabolism , hypersensitive C-reactive protein (hs-CRP) and 24 hours urinary albumin excretion rate (UAER) were analyzed .Results Urea ni-trogen(Urea) ,serum Cystatin C(CysC) ,cretinine(Cr) ,uric acid(UA) ,β2-microglobulin(β2-MG) ,hs-CRP ,low density lipoprotein (LDL-c) .Lp(a) .24h UAER were significantly higher in CN group;Urea ,Cr ,β2-MG ,CysC ,hs-CRP ,ApoA ,lipoprotein A[Lp(a)] , 24 h UAER were significant higher in DN group;Urea ,hs-CRP ,TC ,TG ,HDL-c ,LDL-c ,ApoB ,Lp(a) ,24h UAER were significant-ly highly in NS group;Urea ,Cr ,UA ,β2-MG ,CysC ,hs-CRP ,TG ,LDL-c ,Apolipoprotein b(ApoB) ,Lp(a) ,24 h UAER were signifi-cantly higher in CRF group .Conclusion With the changes of renal function in patients with chronic renal diease ,the lipid metabo-lism and hs-CRP also change .

Objective:To investigate the difference of biological characteristics and responses to PDGF-BB between human ovarian carcinoma-derived microvascular endothelial cells and human umbilical vein endothelial cells.Methods:The ovarian carcinoma-derived microvascular endothelial cells were isolated and purifed from ovarian carcinoma tissues.Compared to the human umbilical vein endothelial cells,the biological characteristics and responses to PDGF-BB were observed in OdMEC for the changes of growth,PCNA and VEGF expression.Results:20ng/ml PDGF-BB could enhance both kinds of endothelial cells to proliferate,express PCNA and VEGF.The proliferation and PCNA protein expression in HUVEC were augmented more significantly than those in OdMEC,the protein and mRNA of VEGF expression were augmented more significantly than those in HUVEC.Conclusion:The responses of OdMEC to PDGF-BB were significantly different from those of HUVEC,which provides experiment basis for research on ovarian carcinoma vascularization and antiangiogenesis therapy.

Objective To study the efficacy of complete hemihepatic vascular exclusion (CHVE) in the prevention of tumour dissemination during liver resection for hepatocellular carcinoma (HCC).MethodsA case-control study was carried out on 281 patients who underwent liver resection for HCC between February 2006 and April 2010.89 patients underwent hepatic resection using CHVE (group A) and 192 using Pringle maneuver (group B).The postoperative 1-,2-,3 year rates of intrahepatic recurrence and lung metastasis,and the overall disease-free survivals were compared between the two groups.ResultsThe incidence of lung metastasis at 1 year after operation was significantly lower in group A than group B (6.7％ vs.15.1％,P=0.048).There were no signilicant differences in the incidences of lung metastasis at postoperative year 2 and 3 between the two groups (15.7％ vs.25.0％ and 32.6％ vs.30.7％ ; P＞0.05).The differences in the postoperative 1-,2-,3- year intrahepatic recurrence rates were not significant between the two groups (20.2％ vs.31.8％,51.7％ vs.60.3％,68.5％ vs.79.2％,respectively; P＞0.05).The median survivals of the two groups were 25.9 months and 21.7 months,respectively.Patients in group A had a significantly higher overall disease-free survival rate than patients in group B (P=0.035).ConclusionsCHVE was efficacious in reducing the incidence of lung metastasis and in improving the overall disease-free survival in patients after liver resection for HCC.CHVE contributed in preventing intraoperative tumour dissemination and in improving prognosis.

Objective To explore the factors influencing health management demand by community residents.Methods Using data from the survey of Health Management Demand by Community Residents in Hangzhou,this paper examined the influence factors with the logistic model from such four aspects as individual characteristics,economic characteristics,health level and health awareness.Results The health awareness poses a positive impact on health management demand;the level of health has a negative impact while income has an inflection point(5 000 yuan per month).However,individual characteristics have no significant effect. Conclusion Such measures as enhancing health management awareness of the residents,building a health management system centering on communities and supported by health management firms,and building health management information platform,can effectively satisfy such demand.

The accelerating pace of exchanges and cooperation in medical field between China and foreign countries demands a large number of medical papers, medical-related materials to be ac-curately translated into multiple languages , especially between English and Chinese . Oriented at English majors (medicine directed), based on eco-translatory approach and student-centered teaching method by creating simulations of the medical English ecological translation environment, this paper provided a better and effective practice-based teaching idea, which can promote students' medical English translation competence and strategies, even cultural consciousness and pragmatic ability in a comprehensive manner.

Eukaryotic cells maintain cellular homeostasis by regulating the process of protein degradation and organelle turnover.Autophagy is a ubiquitin-like degradation process,and plays an essential role in cellular development,differentiation,and elimination of damaged organelles and protein.Previous studies mostly focused autophagy on tumor and neurodegenerative diseases,whereas studies about autophagy and energy remain not clear.Since 2009,an increasing number of studies have showed light on the importance of autophagy in regulating lipid metabolism.The review focuses on the relationship between autophagy and differentiation of adipocytes,lipogenesis,and lipolysis.

Objective To investigate the perioperative nursing demands of elderly patients receiving laparoscopic cholecystectomy ( LC) . Methods A total of 195 elderly patients receiving LC were interviewed .The nursing care demands at admission, preoperation, postoperation, and discharge were collected respectively . Results On the day of admission, all the 195 patients (100%) wished to be aware of their surgeons , 191 patients ( 97.9%) wished to understand causes of disease and its prevention, 189 patients (96.9%) were willing to know the operation costs , and 124 patients (63.6%) wanted to know the influences of basic diseases on operation.During preoperative periods, 194 patients (98.5%) expected to understand the safety and time of operation, 187 patients (95.9%) were interested in the preparedness before operation , and 135 patients (69.2%) wanted to know about the strategy for treating operation stress .During postoperative periods , 195 patients ( 100%) wanted to know the operation process and outcomes , 185 patients ( 94.9%) wanted necessary cares from nurses , 172 patients ( 88.2%) wanted to know the management for postoperative pain , 148 patients ( 75.9%) expected to understand the drug prescription after operation , and 146 patients (74.9%) were interested in diets and physical activities .At the time of discharge, 195 patients (100%) wanted to be aware of reexamination time and follow-up context, 193 patients (99.0%) wanted to know dietary recommendation , and 177 patients (90.8%) were willing to know the exercise options and time . Conclusion Nurses should be aware of the perioperative care demands in elderly patients receiving LC and provide specific care services to reduce complications and improve rehabilitation .