Objective To study the effect of binocular vision function training for fusion in the eye position and three levels of eye function in adult patients after concomitant strabismus surgery. Methods 56 cases with postoperative concomitant strabismus were randomly divided into training group and control group . In the training group, patients were trained with software to enhance the fusion. After training for 7, 30, 180 and 365 days, the eye position, the fusion and the stereoesthesia were observed and analyzed. Results After training for 365 days, the deteriorative ratio in the training group is 3%, which is significantly lower than control group (23%)(P<0.05). The correction ratio in eye position is 20%, which is significantly higher than control group (4%)(P<0.05). The recovery ratio in binocular vision function is 53%, which is significantly higher than control group (15%)(P<0.05). The recovery ratio in stereaeuity is 46%, which is significantly higher than control group (11%)(P<0.05). Conclusions Fusion training can enhance the recovery of fusion and stereaeuity, decrease the deteriorative ratio, and correct the eye position after surgery in concomitant strabismus patients.

ATP-tumor chemosensitivity assay(ATP-TCA)is a tumor chemosensitivity assay in vitro.Beacause of the special merites of A11P-TCA,it is seemed to be the most promising and effective method of tumor chemosensitivity in vitro.Application of ATP-TCA in clinic has got significant effects.ATP-TCA is a good method for individualized chemotherapy.

Objective To investigate the relationship between renal function and lipid metabolism in patients with chronic renal disease .Methods A total of 76 patients with chronic renal disease were enrolled and classified into chronic renal failure(CRF)group (29 cases) ,chronic nephritis(CN)group(21 cases) ,diabetic nephropathy (DN) group(14 cases) and nephrotic syndrome (NS) group (12 cases) ,and 65 healthy subjects were enrolled in control group ,the relationships between renal function ,lipid metabolism , hypersensitive C-reactive protein (hs-CRP) and 24 hours urinary albumin excretion rate (UAER) were analyzed .Results Urea ni-trogen(Urea) ,serum Cystatin C(CysC) ,cretinine(Cr) ,uric acid(UA) ,β2-microglobulin(β2-MG) ,hs-CRP ,low density lipoprotein (LDL-c) .Lp(a) .24h UAER were significantly higher in CN group;Urea ,Cr ,β2-MG ,CysC ,hs-CRP ,ApoA ,lipoprotein A[Lp(a)] , 24 h UAER were significant higher in DN group;Urea ,hs-CRP ,TC ,TG ,HDL-c ,LDL-c ,ApoB ,Lp(a) ,24h UAER were significant-ly highly in NS group;Urea ,Cr ,UA ,β2-MG ,CysC ,hs-CRP ,TG ,LDL-c ,Apolipoprotein b(ApoB) ,Lp(a) ,24 h UAER were signifi-cantly higher in CRF group .Conclusion With the changes of renal function in patients with chronic renal diease ,the lipid metabo-lism and hs-CRP also change .

Under the environment of network,the service mode of subject librarian becomes an important strategy of intelligence serves in university libraries.To provide reference for other librarians,this paper summarizes services provided for the academic researchers by using Web of Knowledge platform resources.

Objective:To investigate the difference of biological characteristics and responses to PDGF-BB between human ovarian carcinoma-derived microvascular endothelial cells and human umbilical vein endothelial cells.Methods:The ovarian carcinoma-derived microvascular endothelial cells were isolated and purifed from ovarian carcinoma tissues.Compared to the human umbilical vein endothelial cells,the biological characteristics and responses to PDGF-BB were observed in OdMEC for the changes of growth,PCNA and VEGF expression.Results:20ng/ml PDGF-BB could enhance both kinds of endothelial cells to proliferate,express PCNA and VEGF.The proliferation and PCNA protein expression in HUVEC were augmented more significantly than those in OdMEC,the protein and mRNA of VEGF expression were augmented more significantly than those in HUVEC.Conclusion:The responses of OdMEC to PDGF-BB were significantly different from those of HUVEC,which provides experiment basis for research on ovarian carcinoma vascularization and antiangiogenesis therapy.

Animals ; China ; epidemiology ; Diabetes Mellitus ; diagnosis ; drug therapy ; epidemiology ; prevention & control ; Humans

Objective To investigate the perioperative nursing demands of elderly patients receiving laparoscopic cholecystectomy ( LC) . Methods A total of 195 elderly patients receiving LC were interviewed .The nursing care demands at admission, preoperation, postoperation, and discharge were collected respectively . Results On the day of admission, all the 195 patients (100%) wished to be aware of their surgeons , 191 patients ( 97.9%) wished to understand causes of disease and its prevention, 189 patients (96.9%) were willing to know the operation costs , and 124 patients (63.6%) wanted to know the influences of basic diseases on operation.During preoperative periods, 194 patients (98.5%) expected to understand the safety and time of operation, 187 patients (95.9%) were interested in the preparedness before operation , and 135 patients (69.2%) wanted to know about the strategy for treating operation stress .During postoperative periods , 195 patients ( 100%) wanted to know the operation process and outcomes , 185 patients ( 94.9%) wanted necessary cares from nurses , 172 patients ( 88.2%) wanted to know the management for postoperative pain , 148 patients ( 75.9%) expected to understand the drug prescription after operation , and 146 patients (74.9%) were interested in diets and physical activities .At the time of discharge, 195 patients (100%) wanted to be aware of reexamination time and follow-up context, 193 patients (99.0%) wanted to know dietary recommendation , and 177 patients (90.8%) were willing to know the exercise options and time . Conclusion Nurses should be aware of the perioperative care demands in elderly patients receiving LC and provide specific care services to reduce complications and improve rehabilitation .

Objective To investigate the effects of Astragalus membranaceus and Angelica sinensis on the hemodynamics and pathological features of arterial wall in restenosis of blood vessel in rats in order to find the potential mechanism of the effect of Astragalus membranaceus and Angelica sinensis in preventing restenosis after ablation of intima. Method Thirty SD rats were randomly divided into 5 groups (6 each):control group (C),model group (M),Astragalus membranaceus treatment group (H),Angelica sinensis treatment group (D),and combined Astragalus membranaceus with Angelica sinensis treatment group (HD). The restenosis model was reproduced by denuding rat's aorta endothelium with balloon catheter in all the groups except group C. After intramuscular injection of Astragalus membranaceus 0.42ml/(kg?d) in group H,Angelica sinensis 0.21ml/(kg?d) in group D,and Astragalus membranaceus 0.42ml/(kg?d) together with Angelica sinensis 0.21ml/(kg?d) in group HD for 21 days,the changes in hemodynamics and the pathological features of arterial wall were observed in all the groups. Result Compared with rats of group C,in which the intima was smooth and the smooth muscle cells (VSMCs) in media were orderly arranged,the intimal thickness of aorta,pulsatile index (PI) and resistance index (RI) increased,while the diameter of lumen,blood velocity decreased remarkably in group M. Compared with the rats in group M,the extent of hyperplasia and thickness was notably reduced,RI and PI were lower while blood velocity was lowered in group H,D and HD after being treated for 21 days. Conclusion Hyperplasia induced by remaval of endothelial cells may be reduced and blood circulation may be improved to different extents by individually or simultaneously use of Astragalus membranaceus and Angelica sinensis,thus preventing restenosis of the aorta after removal of its intima.

For a valid control of the finance management, the management system is developed again aiming at finance related control links and key control points. In this way, the control is rigorous and integral with simple procedures for check and examination. The key control point is set oriented to note management. Real-time operation is controlled. Post output processing is controlled. With business income and business expenditure as the main line, the control process of the related links are built up. Computer maintenance system is controlled.

BACKGROUND:The molecule mechanism underlying endothelial progenitor cells(EPCs) differentiation into mature endothelial cells remains poorly understood.It requires for the regulation of the expression of various genes inside cells by various signal pathways,PI3K/Akt maybe included.OBJECTIVE:To investigate the role of PI3K/Akt in EPCs differentiation.DESIGN,TIME AND SETTING:A group control in vitro experiment was performed at the Pathology Laboratory in Shengjing Hospital of China Medical University from September 2007 to March 2008.MATERIALS:Wistar rats aged 4-6 weeks,of either gender.METHODS:EPCs were isolated from rat bone marrow with density gradient centrifugation.Then difference-speed adherence screening method was used to obtain the second time adherent cells,which then were inoculated in culture flask.After 5 days of culture,cells were collected to be indentified with laser confocal microscopy.The differentiating EPCs were those that have positive results of both AC133 and vWF stainings.MAIN OUTCOME MEASURES:The mRNA and the protein expression of AC133,vWF,PI3K and Akt in EPCs were detected with Western blot and reverse transcription-polymerase chain reaction(RT-PCR) after 0,3,7,10 and 14 days of inoculation respectively.RESULTS:According to the RT-PCR and Western blot detection,AC133 showed the strongest expression at day 0,the weaker at day 3 and none at day 7,10 and 14(P