104 cases of children with malignant lymphoma in our hospital from June 1966 to June 1986 are reported. 84 were males and 20 females. Their ages ranged 6 to 12. These patients were 33 HD, 71 NHL. 9 in stage Ⅰ, 29 in stage Ⅱ, 37 in stage Ⅲ and 29 in stage Ⅳ. In this series B group was 55% (57/104). The clinical primary site of intranodular was 75% (78/104) and extranodular 25%(26/104). The treatment methods include rrdiotherapy alone 16, chemotherapy alone 27 and combination 61. The complete remission (CR) was 30% (31/104), partial remission (PR) 58% (60/104). Total repose rate was 88%. The overall 3 and 5 year survival rates were 26.3%(24/91) and 18%(15/83). Survivals of 10 years were 6 cases (no evidence of disease). It is indicated that the primary sites, clinical stages, pathology types, treatment methods and complete remission are the prognostic factors in children with malignant lymphoma. Errly diagnosis, clinical stage and treatment have been discussed briefly. It is emphasized that after treatment, follow-up and maitaining chemotherapy may prolong the life of the patients.

Objective To assess the feasibility of real-time Bi-Plane in observing normal mitral annular areas in different gestational ages.Methods Routine two-dimensional echocardiography and real-time Bi-Plane were used to observe mitral structure and measure the mitral annular area in 159 fetuses.Pearson correlation analysis was used to evaluate the correlation of the areas with gestational age.Visualization rates and acquisition time were recorded and analyzed statistically.Resuits The mitral annular areas measured by two techniques were both correlated to the gestational age (r=0.71,0.75,both P＜0.05).There were significant differences in visualization rate (x2 =4.375,P=0.036) of mitral annular area and acquisition time (t=6.11,P＜0.05) between routine two-dimensional echocardiography and real-time Bi-Plane.Conclusion Real-time Bi-Plane technique is direct,accurate,convenient and fast in observing mitral prenatally.By using Bi-Plane technique to measure mitral annular area,abnormal morphology changes of mitral valve can be evaluated,so as to provide great application value for clinic.

Using proliferating inhibition test, the effects of three cultivars of black mushroom on the growth of gastric carcinoma cell in vitro were observed. We have found that the extracts of all three cultivars of black mushroom had inhibiting effects on the growth of tumor cells in medium at some levels, especially Cr-02 was the most evident one.The results suggest that black mushroom has some anti-tumor effects, and it is worthwhile to study farther for verification.

Female ; Humans ; Incontinentia Pigmenti ; diagnosis ; pathology ; therapy ; Infant, Newborn

Adolescent ; Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols ; adverse effects ; therapeutic use ; Drug Combinations ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Hematopoiesis ; drug effects ; Humans ; Leukemia, Myeloid, Acute ; drug therapy ; Male ; Middle Aged ; Phytotherapy ; Schisandraceae

The effect of OQP, a pormula of traditional Chinese medieine belonging to the category "Precription of the Reinforeing Qi and Enriching Blood for keep the Original Qi", on cell strain of human hepatic carcinoma SMMC-7721 was observed. The results showed that OQP depressed the incorporation of both ~3H-TdR and ~(14)C-UR in cells of hepatic carcinoma. This indicated that OQP inhibited the synthesis of DNA and RNA, and the growth of the cancer cell. Such effect may result from the low ratio Cu/Zn and the high content of Se in OQP. In conclusion, in this study it has been demonstrated that OQP can not only improve the general condition of patients in advanced liver cancer and lcukopenia of patients in chemotherapy and radiotherapy, but also can inhibite the growth of the cell of hepatic carcinoma directly.

Oseteogenic sarcoma is a kind of malignanttumor of bone, it can occur at any age, teenagersare mose commonly involved. The conventionaltreatment of osteogenic sarcoma was high amputa-tion. Although the primary focuses were removedtotaliy, the subclinical minor focuses could not becontrolled effectively. Therefore. the prognosiswas very poor, the five-year survival rate was on-ly about 20 percent. With the rapid development inchemotherapy and orthopedical surgery tech-niques, multimodality therapy of osteogenic sarco-ma were carried out in 65 cases from 1982 to 1988in our hospital. Curative effect has been satisfac-torily improved. The fivc-year survival rate hasbeen raised to 67. 92%. The methods of multi-modality therapy were as follows: ①Peroperationand postoperation chemotherapy with p?liod ofbody. ②Local arteries were perfused with Nitero-gen mustard (HN_2). ③Inactivation of tumor celland replantation. ④Inactivation of tumor cells invivo. ⑤Amputation.

Objective: To investigate the effects of bovine plasma fibronectin on the proliferation and differentiation of rat osteoblasts. Methods:Rat osteoblasts were cultured and identified. AlamarBlue were used to determine the effect of various concentration of bovine plasma fibronectin on the proliferation of the osteoblasts. ELISA method was used to determine the alkaline phosphatase activity of the cells. Results: Fibronectin stimulated the proliferation of rat osteoblasts at 40 ?g/ml (P

Objective To investigate the clinical efficacy of Zusanli moxibustion intervention in abdominal distention with enteral nutrition after stomach cancer surgery.Methods One hundred patients who had undergone stomach cancer surgery and received postoperative enteral nutrition were randomly allocated to treatment and control groups, 50 cases each. The control group received medication and the treatment group, Zusanli moxibustion in addition. Post-treatment incidences and grading scores of abdominal distention were compared between the two groups.Results The incidence of abdominal distention was 6.0% in the treatment group and 24.0% in the control group; there was a statistically significant difference between the two groups (P<0.05). The grading score of abdominal distention was (0.33±0.58) in the treatment group and (0.92±1.00) in the control group; there was a statistically significant difference between the two groups (P<0.05).Conclusion Zusanli moxibustion can effectively prevent the occurrence of abdominal distention in patients with enteral nutrition after stomach cancer surgery.

ISO 15189 standard quality management system developed by the International Organi-zation for Standardization (ISO) embodies the international medical laboratory's latest quality management concept, and puts forward the quality improvement method of the standard. In this research, ISO 15189, as an important content in practice teaching for laboratory medicine, was designed according to the elements of this system. Students were requested to participate in every linkage of laboratory quality management by writing system document, taking part in quality activity, and practicing the key and difficult points of tech-nique in quality system in order not only to cultivate their basic idea of ISO 15189 standard, but also to make them familiar with the basic patterns of laboratory accreditation system and process, which could make them become the backbone of the laboratory quality management quickly in their vocational positions in the future.