Objective To investigate the clinical effects of the traditional rehydration and sub-shock therapy for pre-hospital treatment of traumatic shock.Methods Two hundred and sixteen patients with traumatic shock,were divided into two groups by random digits table:group A (103 cases) and group B (113cases).Group A was treated by traditional rehydration method,group B was treated by sub-shock therapy.The mortality,incidence of serious complications,and laboratory parameters between two groups were compared.Results The total mortality in group A was significantly higher than that in group B [38.8％ (40/103) vs.25.7％ (29/113),P ＜ 0.01].There was no statistically significant difference in ＜ 1 h,＞ 2 h mortality between two groups (P＞ 0.05).The 1-2 h mortality in group A was significantly higher than that in group B [18.4％(19/103) vs.8.0％(9/113),P ＜ 0.05].The incidence of serious complications in group A was significantly higher than that in group B [41.7％ (43/103) vs.21.2％ (24/113),P ＜ 0.01].Treatment of 1 h various laboratory parameters in group B were significantly better than those in group A (P ＜ 0.01 or ＜0.05).The average amount of fluid in group A was significantly more than that in group B [(2352.6 ± 763.1)ml vs.(592.4 ±236.3) ml,P ＜0.01].There was no statistically significant difference in systolic blood pressure between two groups (P ＞ 0.05).Conclusions Sub-shock therapy in pre-hospital emergency treatment of traumatic shock has some advantages compared with traditional rehydration method,which is conductive to the maintenance of the patient' s vital signs,to reduce bleeding and improve patient treatment rate.

Snake antivenomimmunoglobulins are considered to be the most efficient drugs in snake envenomings. Most snake antivenomimmunoglobulins all over the world are still prepared by fragmentation of polyclonal antibodies isolated from hyper-immunized horse serum till now. In this review, we retrospect the history of snake antivenomimmunoglobulins, analysis the present situation and pay the close attention on the key technological links in the process of research and manufacturing, such as properties of IgG and its fragments, selection and preparation of immunogen, optimization of immunization schedule and protein isolation and purification, which can be available for the reference in the research and development of snake antivenom.
Animals ; Antivenins ; pharmacology ; Humans ; Immunoglobulin G ; pharmacology ; Snake Bites ; drug therapy ; Snakes

30 mmHg on day 1 after SLT.Blurring and anterior uveitis were controlled. Conclusion SLT may be a safe and effective therapy for POAG.

Adult ; Arteriovenous Malformations ; Humans ; Male ; Telangiectasia, Hereditary Hemorrhagic

Endoscopy ; Humans ; Male ; Middle Aged ; Myoepithelioma ; surgery ; Nasal Septum ; pathology ; Nose Neoplasms ; surgery

OBJECTIVE:To compare the extraction yield of total flavonoids from fine powder vs.ultrafine powder of Gleditsia sinersis.METHODS:The absorbance was detected under a wavelength of 510 nm by ultraviolet spectrophotometry. The extraction rates of flavonoids from fine powder vs.ultrafine powder of Gleditsia sinersis were computed.RESULTS:The extraction rate of flavonoids from ultrafine powder was 29.1%higher than that from the fine powder of Gleditsia sinersis. CONCLUSION:The extraction rate of flavonoids was increased by superfine comminution.

Objective To discover the role of interleukin-18(IL-18) and CD_(54) in congestive heart failure(CHF),and evaluate the diagnostic value of IL-18 and CD_(54) in CHF.Methods Blood samples were collected from 52 children with CHF,included 18 cases in classⅡ,17 cases in class Ⅲand 17 cases in class Ⅳ.Fifteen healthy children were normal control group.The levels of IL-18 was(detec-)ted by ELISA method and the expression of CD_(54) was examined by flow cytometry.Results The levels of IL-18 and CD_(54) in CHF were significantly higher than those of control subjects(P0.05),but the levels were respectively significantly higher than that of control subjects(P

Adult ; Angiofibroma ; Humans ; Male ; Nose Diseases ; Turbinates ; pathology

Congresses as Topic ; Laryngeal Diseases ; Otolaryngology ; Pediatrics ; Pharyngeal Diseases

21 mmHg.The side effects,IOP and application of anti-glaucoma drugs were examined 1 h,1 d,1 week,1 month,3 months and 6 months after SLT. Results The IOP was significantly decreased 1 week,1 month,3 months and 6 months after SLT compared with that before treatment(P21 mmHg using two anti-glaucoma drugs,respectively. Conclusion SLT is a safe and effective method for IOP control in early CPACG after treatment with laser peripheral iridoplasty and laser iridectomy.