Objective To explore the clinical effect of adenovirus dipivoxil combined with Anluohuaxian pill in the treatment of chronic hepatitis B cirrhosis .Methods 98 patients with chronic hepatitis B liver cirrhosis were randomly divided into the two groups .49 cases in the control group were treated with adenovirus dipivoxil ,and 49 ca-ses in the observation group were given adenovirus dipivoxil combined with Anluohuaxian pill .The clinical effect of two groups was observed .Results The total effective rate of the observation group was 92.9%,which was significant-ly higher than 69.4% of the control group (χ2 =9.37,P<0.05).Before treatment,the alanine aminotransferase (ALT),hyaluronic acid (HA) and albumin/globulin (A/G) between the observation group and the control group had no significant differences (t=0.213 1,1.212 2,0.403 2,all P>0.05).After treatment,the ALT,HA and A/G of the two groups were significantly improved compared with those before treatment ,the improvement of the observation group was better than control group ,the difference was statistically significant ( t=11.302 1,9.012 1,7.312 4,all P<0.05).Conclusion In clinical practice,adenovirus dipivoxil combined with Anluohuaxian pill in the treatment of patients with chronic hepatitis B cirrhosis has good therapeutic effect ,it can improve the clinical symptoms and pa-tients'liver function ,so as to improve the liver detoxification function and the clinical treatment effect ,which worthy of clinical application and promotion .

The drug and medical consumables management center in Wuhu features the operational mechanism separating the decision-making power of drug purchasing,the executive power and the supervision power.This practice terminates the interest chain previously found between medicine suppliers with hospitals,pharmacies and doctors,creating the Wuhu Model of drug and medical service separation at public hospitals.The drug zero-profit policy reshapes the drug supply system and the existing compensation mechanism of public hospitals,further defining the Wuhu Model.This model is paving the way for the same reform to be carried out nationwide.

The separation of drug and medical service is key to alleviating the social problem of high medical expenses,and the top thing to do is to cut off the profit link found in the drugs purchase and sales interests chain.Pharmacies of the hospital are found to play a crucial role in this chain,as they not only take part in the decision-making of drug purchase but also directly purchase and dispense drugs.Wuhu has established the Medicine and Medical Consumables Management Center,which directly regulates the pharmacies and detach them from this chain,weakening their rent-seeking power.Practices of this reform found the pharmacies no longer playing a dominant role in drug purchase/dispensation on one hand,and yet less incentives of the pharmacies due to management by the Center on the other,resulting in poorer pharmaceutical management of the hospital as a result.In this consideration,pharmacies have experienced a detachment and return process from their hospital in the reform of drug and medical service separation in Wuhu.Experiences prove the correct way out is to guide the pharmacies to upgrade from logistics in drug supply to innovated services,thus better serving hospital management.

Objective To investigate the clinical features of pregnancy complicated severe hepatitis and summarize experience in diagnosis and treatment so as to decrease maternal mortality.Methods Forty-two cases of pregnant women with severe hepatitis in the hospital were retrospectively analyzed.According to the outcome,all subjects were divided into death group(27 cased) and survival group(15 cases).Clinical data including viral markers,clinical manifestations,blood biochemistry,clinical treatment and pregnancy outcomes were recorded.Results (1) Pathogen examination showed that the major infection was hepatitis B virus (HBV),accounting for 64.29％ (27/42).(2) The first symptoms was gastrointestinal symptoms,accounting for 73.81％ (31/42).(3) The level of serum albumin,cholesterin (CH) and cholinesterase (CHE) in survival group were (29.91 ± 6.78) g/L,(2.80 ± 1.02) μmol/L and (5 399.4 ± 1 096.5) U/L respectively,significantly higher than that in death group((25.14 ± 7.36) g/L,(1.73 ± 0.77) μmol/L,(3423.6 ± 1102.7) U/L respectively).The serum creatinine(SCr) and prothrombin time (PT) levels in survival group were (83.06 ± 47.23) μ mol/L,(18.98 ± 6.72) s,lower than that in death group ((231.54 ± 58.90) μmol/L,(44.16 ± 5.38) s).The differences were statistically significant (t =2.07,3.84,5.57,8.37,13.29 ; P ＜ 0.05 or P ＜ 0.001).(4) The mortality rate of patients who chose pregnancy termination was 31.58％ (6/19),lower than the overall average mortality rate 64.29％ (27/42) and the difference was statistically significant (x2 =5.636,P =0.018).Conclusion HBV infection is the main reason for pregnant women with severe hepatitis.Gastrointestinal symptoms is the main symptom.Serum albumin,SCr,PT,serum CH and CHE can be regarded as prognostic indicators of the disease.Active comprehensive treatment and timely pregnancy termination can reduce maternal mortality.

Acupuncture Points ; Acupuncture Therapy ; Aged ; Catgut ; utilization ; Combined Modality Therapy ; Constipation ; drug therapy ; therapy ; Drugs, Chinese Herbal ; administration & dosage ; Female ; Humans ; Male ; Middle Aged

Acute Disease ; Aged, 80 and over ; Fibrin Fibrinogen Degradation Products ; analysis ; Humans ; Male ; Pulmonary Embolism

Female ; Hemangioma ; therapy ; Humans ; Infant, Newborn ; Syndrome ; Thrombocytopenia ; therapy

Female ; Fetal Diseases ; etiology ; Hemangioma ; complications ; Humans ; Infant, Newborn ; Splenic Rupture ; etiology ; Thrombocytopenia ; complications

AIM: To study the correlation between the drug effects and serum HPLC fingerprint from active compositions of Radix paeoniae alba and Radix et Rhizowa Glycyrrhizae. METHODS: Orthogonal design of L_9(3~4) of the different combinations of three active compositions of paeoniflorin,glycyrrhiza flavoues and Glycyrrhizic acid were prepared,antalgic pharmacological experiments of mice were carried out.The fingerprints of the serum were tested by HPLC method and different chromatographic peaks were obtained.Correlation analysis was applied to interelationship between the area of each peaks and the pharmacologic data. RESULTS: Correlation coefficients were different between pear areas and analgetic coffec. CONCLUSION: This study provides a significant try of investigating the compatibility of composite herbal medicines.

Objective To evaluate the laparoscopic repair for indirect inguinal hernia in children. Methods A total of 72 children with unilateral and 25 children with bilateral indirect inguinal hernia underwent laparoscopic high ligation of the sac. In operation a self-made needle introduced subperitoneally was used to pass a ligature circumferentially around the internal ring. Results All the operations were successfully completed. The average operating time was 10 min in unilateral hernias and 16 min in bilateral hernias. The postoperative hospital stay was 1 day. No surgical complications occurred. Follow-up for 2~60 months (mean, 31 months) in 70 children found no recurrence. Conclusions Laparoscopic repair for indirect inguinal hernia in children is safe, feasible and minimally invasive, offering a low complication and recurrence rate and a quick postoperative recovery.