The basic research and development of xeno-transplantation technique has been a new field. The article analyzed its current situation and problems, discussed the ethical problems the researchers and physicians faced, and raised a series of ethical principles which should be obeyed in xeno-transplantation, that is: stick to combining humanism and utilitarianism; observe the technological and sanitary criterion, choose the graft cautiously; Be attentive and loyal to the recipient's health; no harm and beneficial to the humankind. Besides, the article explored the importance of setting up laws and regulations about xeno-transplantation.

Hypercholesterolemia and coronary heart disease caused by it have become the most important factors threatening human health. The lipid metabolism-related studies are increasingly receiving attention. Recent studies have demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK9), a family member of precursor protein-converting enzyme, plays an important role in the regulation of lipid metabolism. The expression and mutation of PCSK9 gene are closely correlated with the content of low-density lipoprotein receptor (LDLR). The excessive expression of PCSK9 promotes the degradation of LDLR, thereby increasing the levels of plasma LDL; whereas the inhibition of PCSK9 gene expression causes the decreased levels of plasma LDL. Therefore, it is promising to develop novel medications for treating hypercholesterolemia, controlling hyperlipermia and preventing coronary heart disease by studying the mechanism of PCSK9.

Objective To study and compare the effects of different surgical operation in treatment of adolescent idiopathic seoliosis. Methods 70 patients with adolescent idiopathic seoliosis and patients informed consent were selected as research object,and they were divided into group A 35 cases and group B 35 cases according to their willingness, and they were separately treated with videoassisted anterior thoracoscopic correction and traditional anterior thoracoscopic correction, then the surgical time, complications, hospital stays, rates of patients satisfaction, total effective rate and Cobb, before and after the treatment were detected and compared. Results The surgical time [(225.6 ± 30. 8) min] and hospital stays [(2. 7 ± 0. 8) d] of group A were all shorter than those of group B [( 365. 4 ±23. 8) min, (4. 8 ± 1.2 ) d] ( t = 3.26,3.78, all P ＜ 0. 05 ), complications rate ( 8. 6% ) was lower than that of group B (20. 0% ) ( x2 = 3. 45, P ＜ 0. 05 ), rates of patients satisfaction ( 97. 1% ) and total effective ( 97. 1% ) were higher than those of group B(80. 0% ,85.75% ) (x2 =2. 85,3.01 ,all P ＜0.05) ,Cobb( 14. 2 ± 5.4)°was smaller than that of group B(23. 4 ±5.6) °(t =2. 97 ,P ＜ 0. 05). Conclusion The effect of vidcoassisted anterior thoracoscopic correction in treatment of adolescent idiopathic seoliosis was good,and complications rate was low and it was worthy of extend and application.

So as to explore the relationship between hypertension happen and combined phlegm and blood stasis,aswell as relations to fi ve zang-viscera,we analysis and study the related articles in literatures of past dynasties about phlegm,blood stasis with dizzy and headache,fi ve zang-viscera with dizzy and headache.We fi nd that there are relationships between phlegm and dizzy and headache,between blood stasis and dizzy and headache,between fi ve zang-viscera and dizzy and headache,as well as between phlegm,blood stasis and disorders of functions of fi ve zang-viscera.Thus,phlegm induces dizzy and headache,blood stasis induces dizzy and headache,the disorders of functions of fi ve zang-viscera cause phlegm or blood stasis,and the diseases of fi ve zang-viscera induce dizzy and headache.Therefore,the happen of dizzy and headache in hypertensive disease has direct or indirect relationships with diseases of fi ve zang-viscera,which should be noticed in clinical treatment.In clinical practices,we fi nd that in the f ive zang-viscera,the heart and kidney have the close relationship with hypertension.In literatures of past dynasties,the discuss about combined phlegm and blood stasis inducing diseases can be found,but there are no records about combined phlegm and blood stasis inducing dizzy and headache,though that is one of the most important pathological factors of hypertension happen in clinical treatment,so we should pay attention to combined phlegm and blood stasis in the treatment of hypertensive disease.

Objective To investigate the effects of Astragalus membranaceus and Angelica sinensis on the hemodynamics and pathological features of arterial wall in restenosis of blood vessel in rats in order to find the potential mechanism of the effect of Astragalus membranaceus and Angelica sinensis in preventing restenosis after ablation of intima. Method Thirty SD rats were randomly divided into 5 groups (6 each):control group (C),model group (M),Astragalus membranaceus treatment group (H),Angelica sinensis treatment group (D),and combined Astragalus membranaceus with Angelica sinensis treatment group (HD). The restenosis model was reproduced by denuding rat's aorta endothelium with balloon catheter in all the groups except group C. After intramuscular injection of Astragalus membranaceus 0.42ml/(kg?d) in group H,Angelica sinensis 0.21ml/(kg?d) in group D,and Astragalus membranaceus 0.42ml/(kg?d) together with Angelica sinensis 0.21ml/(kg?d) in group HD for 21 days,the changes in hemodynamics and the pathological features of arterial wall were observed in all the groups. Result Compared with rats of group C,in which the intima was smooth and the smooth muscle cells (VSMCs) in media were orderly arranged,the intimal thickness of aorta,pulsatile index (PI) and resistance index (RI) increased,while the diameter of lumen,blood velocity decreased remarkably in group M. Compared with the rats in group M,the extent of hyperplasia and thickness was notably reduced,RI and PI were lower while blood velocity was lowered in group H,D and HD after being treated for 21 days. Conclusion Hyperplasia induced by remaval of endothelial cells may be reduced and blood circulation may be improved to different extents by individually or simultaneously use of Astragalus membranaceus and Angelica sinensis,thus preventing restenosis of the aorta after removal of its intima.

The compounds were isolated from Aoonitum coreanum (Lev1.) Rapaics and identificd by TLC, IR, MS and NMR, as ?-sitosterol (Ⅰ), daucosterol (Ⅱ), Guan-Fu base A (Ⅲ),GuanFu bas. G (Ⅳ), condelphine (Ⅴ), Guan-Fu base Ⅰ (Ⅵ), hetisinone (Ⅶ), isoatisinum chloride (Ⅷ), atisinum chloride (Ⅸ), and Guan-Fu base z (Ⅹ) from the root. Compounds Ⅲ and Ⅸ were also found in the aerial parts of the plant. compounds Ⅱ, Ⅴ, Ⅶ and Ⅷ were obtained for the first time from this plant. Most of them exhibited antiarrhythmic activlty.

The enzyme,as a biocatalyst,can not be surpassed in speeding up the reactions by other common chemical catalysts under the suitable conditions and can catalyze the reaction mildly,simplify the facilities needed,improve the work conditions,and reduce the production costs,etc.Those are its advantages mentioned above.But while the enzyme is extracted outside the cells,the molecular conformation may be changed with decreasing its bioactivity and stability seriously.As one type of physical energy,(ultrasonic) wave with lower intensity and suitable frequency can make the conformation of enzymatic molecular comformation transform positively and the transforming reactions accelerate so as to facilitate the effective constituents of Chinese materia medica and natural products transforming.

Objective To establish a numerical model of adsorption and desorption of CO_2 and to study the influencing factors on the removal system. Method A physical model was expressed by mathematical method, then an isothermal adsorption model for simulating molecular sieve was established. Result The working process of a CO_2 removed device was simulated and its result was analized with the established model.The characteristics of the adsorption and desorption was obtained. Conclusion The model describes the processes correctly, the influencing factors like humidity dimension of the bed are considered simultaneously.It remains to be improved by further experimental corrections.

Because of insufficient intake,synthesis disorder,metabolic disorder and excessive consumption,patients with cirrhosis often lead to malnutrition. Providing scientific nutritional support and guiding the patients to a reasonable diet can effectively improve the liver metabolism and reduce the complication of cirrhosis such as hepatic encephalopathy,and improve the quality of life and survival rate. This article described the nutritional metabolism disorder in patients with cirrhosis and nutritional treatment in hepatic encephalopathy.