This article reviewed the application of different kinds of imaging methods combined with the analysis of brain connectome in mild cognitive impairment. Previous studies demonstrated that the brain worked as the small-world network. In patients with Alzheimer's disease or mild cognitive impairment, the structure of small-world of network might be changed. According to the different methods, the trend of those changes might be different. This paper reviewed the current situation of the study in mild cognitive impairment through brain network analysis, and emphasized its importance and prospects.

Objective To investigate the clinical characteristics,treatment options and prognosis of duplex kidneys in children.Methods Data were retrospectively collected from all patients who were hospitalized at Shengjing Hospital Affiliated to China Medical University from January 2008 to May 201 5.The surgery to retain moie-ty nephron was performed in 30 cases:1 2 cases underwent non common sheath ureter reimplantation,4 cases of the patients had common sheath ureter reimplantation,1 2 patients underwent transurethral resection of the cyst,1 case of them had pyeloureterostomy,and the other patients underwent lower -pole pyeloplasty.Removal of renal moiety was performed in 52 cases:43 patients underwent upper -pole heminephrectomy,8 patients underwent upper pole hemi-nephrectomy and lower -pole ureter reimplantation,and 1 case of the patients had upper -pole heminephrectomy and lower -pole ureteroplasty.Results A total of 54 cases were followed up,the follow -up rate reached 65.9%,the follow -up time lasting 2 months to 4 years,with an average time of 9.53 months.All clinical symptoms disappeared after remove moiety operation.There were small ureteral cysts but compared with the preoperative condition,the symp-toms reduced significantly in 4 cases.All clinical symptoms disappeared in patients whose nephron was retained after operation,and hydronephrosis was alleviated.De novo 2 degree of vesicoureteral reflux was found in 3 out of 1 2 pa-tients who underwent transurethral puncture of the cyst.Conclusions The clinical manifestations of duplex kidney have some characteristics which include recurrent urinary tract infection,normal intermittent voiding urine dripping, abdominal pain,urethral orifice mass,abdominal mass and aggravation of hydronephrosis.Duplex kidney is often asso-ciated with cardiac malformation and cryptorchidism.The preoperative testicular examination and echocardiography should be performed.The choice of operation depends on the clinical manifestation,auxiliary examination results and comprehensive analysis.The prognosis of duplex kidney is well,but patients need to be further followed up af-ter operation.

Vaccination in children suffering neurological diseases is a troublesome issue that people es-pecially pediatricians are reluctant to mention. Due to worrying about the emergence of adverse reactions and concerning on the heat induced seizure,doctors and parents tend to cancel or do not recommend these children to be vaccinated. Additionally,the heat sensitive seizures,such as febrile seizure( FS) ,generalized epilepsy with fe-brile seizure plus(GEFS+),Dravet syndrome account for the largest proportion of the seizure related disease and epilepsy syndrome. Their pathogenesis has been proved relating to the mutation of SCN gene of the sodium channel. For children with FS,GEFS+,and Dravet syndrome,vaccination may lead to fever,which even may bring about convulsions,but it will not result in worse prognosis.

Objective To detect serum levels of 25 ? hydroxyvitamin D (25 [OH] D) and matrix metalloproteinase 9(MMP?9)in patients with chronic spontaneous urticaria(CSU), and to explore their significance. Methods Totally, 56 patients with CSU and 25 healthy controls were enrolled into this study. High?performance liquid chromatography tandem?mass spectrometry(LC?MS/MS)and enzyme?linked immunosorbent assay(ELISA) were performed to measure serum levels of 25(OH)D and MMP?9 respectively in these subjects. Statistical analysis was carried out by two independent samples t?test or Wilcoxon rank sum test for comparisons of the above indexes between the two groups, and by Spearman rank correlation analysis for assessment of relationships between the serum levels of 25(OH)D and MMP?9 as well as between the two indexes and disease severity. Results Of the 56 patients, 19 were diagnosed with mild CSU, 26 with moderate CSU and 11 with severe CSU. Compared with the control group, the patient group showed significantly lower serum levels of 25(OH)D(21.74 ± 6.04 vs. 30.17 ± 2.21μg/L, P<0.05), but significantly higher serum levels of MMP?9(Median[P25-P75]:291.55[166.18-594.46]vs. 138.46[94.27-233.12]μg/L, P<0.05). In the patient group, the serum level of 25(OH)D was negatively correlated with that of MMP?9 (rs=-0.26, P<0.05), but uncorrelated with the severity of CSU(rs=-0.20, P>0.05);the serum level of MMP?9 was positively correlated with the severity of CSU(rs=0.27, P<0.05). Conclusion Vitamin D and MMP?9 may play a role in the occurrence of CSU.

Objective To investigate the nurses′ styles of handling interpersonal conflict and jobachievements,and analyze the relationships between them.Methods A total of 610 nurses in four hospitals were recruited by convenience sampling method and investigated with general state scale,the Rahim Organitional Conflict Inventory- Ⅱ and the Job Performance Appraisal Scale for nurses in four hospitals,the results underwent analysis.Results The factor scores of the Rahim Organitional Conflict Inventory- Ⅱwere sent in the descending order as integrating,avoiding,obliging and dominating.The factor scores of jobachievements were sent in the descending order as task,situation,anti-product.Integrating was positively correlated with task and situation,negatively correlated with anti-product,obliging was negatively correlated with task,positively correlated with anti-product.Conclusions Integrating styles of handling interpersonal conflict benefits to accomplish nurses′ job achievement.

Liquid therapy is a vital method of perioperative treatment.Choosing correct kinds of transfusion and reasonable therapy strategies can significantly reduce the perioperative complications and shorten days in hospital and improve the critical patients prognosis.The historical development of perioperative liquid therapy is a forward process,which is about crystalloids vs.cilloid,dry vs.wet,and other controversial problems continuing to be summarized,explored and discussed.In this process,there are some specific perioperative treatment strategies with the physician having a deeper cognitive,such as goal-directed therapy,early goal directed therapy and fast track surgery which have significant clinical curative effect.This article summarizes the advance of perioperative liquid therapy.

An improved method for the determination of Vitamin D2 in baby food (fortified dried milk) was established by using two steps of high-performance liquid chromatography (HPLC). The sample was directly saponified and extracted with benzene. The extracted unsaponifiable matter was firstly subjected to preparative HPLC using a Nucleosil 5C18 column (reversed-phase type) with acetonitrile-methanol (3:2) as a mobile phase. This first step was for the purpose of clean-up, and a fraction containing Vitamin D2 was collected. The separate fraction was subsequently subjected to analytic HPLC with a Zorbax SIL column (straight-phase type) with isopropanol-hexane (0.8 : 99.2) as a mobile phase. The Vitamin D2 was separated from other contaminants and determined with ultraviolet spectrograph by the peak height estimated. The recovery rate was 84%, standard deviation 12.57 and coefficient of variation 4.57%. The proposed method was rapid, accurate, and suitable for the determination of baby food.

OBJECTIVE:To classify the herbs for promoting blood circulation to remove blood stasis.METHODS:Database of 33 commonly used herbs for promoting blood circulation to remove blood stasis was established by means of SPSS10.0 software package;and the nature,tastes,meridian attributions and actions of the herbs were collected as variables showing the characteristics of classification,and the names of the herbs served as variables for measurement to proceed Q Cluster in Hierarchical Cluster.RESULTS:When the herbs were classified into 4 groups,the first group included the herbs for promoting blood circulation to restore menstrual flow,the second the herbs for promoting blood circulation to arrest pain and dissipate tumor,the third the herbs of herbs for activating blood circulation to dissipate blood stasis and kill pain,the fourth the herbs for severely activating blood circulation to dissipate blood stasis.When the herbs were classified into 5 groups,the fifth group included herbs for activating blood circulation to cure wound.When the herbs were classified into 6 groups,the third one included the herbs for activating blood circulation to exclude wind and the sixth the herbs for activating blood circulation to stanch blood.CONCLUSION:Fuzzy grouping analysis can be applied to classify herbs of different kinds yet with the same efficacy and to classify the same group of herbs according to their drug actions.

In the past, education of acupuncture/ moxibustion in Taiwan depended on the masters-disciples relation. The knowledge of acupuncture/ moxibustion was transmitted to disciples individually.
Since its establishment in 1955, The Taipei Society Acupuncture and Moxibustion improved educational pro- gram to more systematic one. In the following 20 years varieties of studies in this field were conducted, people also turned their eyes to these traditional remedies
Though acupuncture and moxibustion had begun to be accepted by people, the new medical law was en- forced in 1975, which disqualified the acupuncturists for medcial practice. As a result, many of the acupuncturists and moxibustionists left Taiwan for overseas. Unlike many other nations, Taiwan has no system for certification of acupuncturists/ moxibustionists. The traditional Chinese doctor in Taiwan, after passing the examination for Chinese Medicinal exam can practice the Chinese herbal medicine and the acupuncture/ moxibustion. It seems an inconceivable system.
It is only after 1989 that the subjects on acupuncture/ moxibustion medicine were included in the exams for the traditional Chinese doctor in Taiwan. But it still doesn't include tests of practical skills. This is more of a hindrance than a contribution to acupuncture and moxibustion in Taiwan.
Though there has been the legalization movement for acupuncturists/ moxibustionists during the past 30 years, it met opposition from both of the health bureau and the traditional Chinese doctor trade union. The license system for acupunturist is still left uncertain.
Now in Japan, the high tech device like electronic microscope, micro inductor and micro-electric are introduced in the studies of acupuncture/ moxibustion medicine. And in the field of scientific research of the acupuncture and moxibustion, Japanese seem to have more grant view than other country. The health government of Taiwan should turn their eyes to the reality and change its policies towards this effective medicine.
Now acupuncture and moxibustion medicine has become one of the international research topics. In recent years WFAS academic congresses are held every year in the different nations. Here I would like to suggest that in advanced country like Japan, a new university specializing in acupuncture/moxibustion medicine should be established and it should accept and educate foreign student from overseas with international curriculum. Only the continuous and faithful exchange of the young scholars would recover the true friendship between Taiwan and Japan.

Objective To discuss the safety management of hemodialysis equipment for safe and effective treatment to patients.Methods The management methods were summarized in aspects of the installation,utilization and maintenance of hemodialysis equipment.Results The hemodialysis patients received the safe and effective treatment through the strict management and the standardized system.Conclusion The standardized management can not only reduce the unnecessary failures of the equipment,and prolong the service life,but also increase the utilization rate of the equipment,and provide the best,safest and most satisfactory treatment for patients.