1.Experience of invocation of contingency plan of prevention from gas gangrene after earthquake
Ping HE ; Anqin ZHANG ; Yihui ZHANG
Chinese Journal of Practical Nursing 2009;25(1):7-8
Objective To explore a salvaging and nursing pathway of gas gangrene following trauma during seismic disaster.Methods The contingency plan of prevention was invocated to physically and psychologically salvage and nurse 18 sufferers having gas gangrene following trauma. Results The illness state of 18 sufferers were all effectively controlled and straightened up.The psychic trauma were pacified and no cross infections took place.Condusions Contingency plan of prevention from gas gangrene directs medical staff how to salvage gas gangrene after disaster,ensure the unblock green life passage for salvaging of patients with gas gangrene.
2.Corrosion resistance of 3M nickel-titanium arch wires and Damon copper-nickel-titanium arch wires in different artificial saliva with different fluoride and pH
Yihui XIONG ; Yunan LI ; Xiaoshuang ZHANG
Chinese Journal of Tissue Engineering Research 2014;(16):2506-2511
BACKGROUND:In the fluorine-containing acidic environment, it is unclear whether Damon copper- nickel-titanium arch wire can have a corrosion resistance similar to conventional nickel-titanium arch wire and whether copper ion wil affect its corrosion resistance. OBJECTIVE: To evaluate the corrosion resistance of 3M nickel-titanium arch wires and Damon copper-nickel-titanium arch wires in artificial saliva with different fluoride and pH. METHODS:Potentiodynamic polarization curves of 3M nickel-titanium arch wires and Damon copper-nickel-titanium arch wires were measured in four kinds of artificial saliva (pH=7; pH=7, 0.2% fluoride; pH=7, 0.5% fluoride; pH=5, 0.5% fluoride). Then, the corrosion potential, corrosion current density and polarization resistance were acquired, and scanning electron microscope was used for morphological observation after corrosion. RESULTS AND CONCLUSION: In neutral (pH=7) artificial saliva, 0.2% fluoride ions added could shift up the Damon specimen polarization curve, increase the corrosion cerrent density and reduce the polarization resistance (P < 0.05); under the scanning electron microscope, corrosion was observable on the specimen surface. But 3M specimen polarization curve did not move, corrosion current density and polarization resistance substantialy unchanged (P > 0.05), and no significant corrosion was produced. When fluoride concentration was increased to 0.5%, the polarization curves of two kinds of the specimens moved, the corrosion cerrent density increased, the polarization resistance decreased (P < 0.05), and there was significant presence of corrosion on the specimen surface. When pH=5, corrosion phenomenon was more pronounced. These findings suggest that low concentrations fluoride cannot affect corrosion resistance of 3M arch wire, but can reduce the corrosion resistance of Damon arch wire; high concentrations of fluoride and acid can both reduce their corrosion resistance. In addition, the corrosion resistance of 3M arch is stronger than that of Damon arch wire.
3.Application of ballonet gastric tube in patients after the operation of esophageal carcinoma
Qinghua MA ; Ping JIA ; Yihui ZHANG
Chinese Journal of Practical Nursing 2008;24(26):14-15
Objective To compare the Occurrence rate of unplanned extubation(UEX)and anastomotic leakage by two different gastric tube for gastrointestinal decompression in patients after the operation of esophageal carcinoma.Methods Three hundred and eighty patients were randomly divided into two groups,the experimental group(n=90),ballonet gastric tubes were used;the control group(n=90),general gastric tubes were used.The occurTence rate of unplanned extubation(UEX)and anastomotic leakage were investigated.Results There was a remarkable difference(P<0.01)in the rate of UEX between the experimental group and the control group.Though no statistical difference was seen in the rate of anastomotic leakage(P>0.05),lower incidence of anastomofic leakage was seen in the experimental group.Conclusions BalIonet gastric tube for gastrointestinal decompression in patients after the operation of esophageal carcinoma can reduce the rate of UEX,improve the nursing qualiy and also successfully reduce the rate of anastomotic leakage.
4.Effect of Group A Streptococcus Preparation combined with mitomycin and lentinan combined with mitomy-cin in the treatment of malignant pleural effusion through intrapleural catheter
Yihui ZHANG ; Jiawei REN ; Qingwen ZHANG ; Ke YANG
Chinese Journal of Primary Medicine and Pharmacy 2016;23(13):1975-1977,1978
Objective To explore the effect and side effects of Group A Streptococcus Preparation(Sapylin)com-bined with mitomycin and lentinan combined with mitomycin in treating malignant pleural effusion through intrapleural catheter.Methods 70 malignant pleural effusion patients were selected in this study.All the patients were randomly divided into Sapylin group and lentinan group.One case with penicillin positive of the Sapylin group was adjusted to enter the lentinan group.After drainage of pleural effusion,the patients were divided into Sapylin group (34 patients) and lentinan group (36 patients).For the Sapylin group,Sapylin was prior injected and mitomycin was posterior injected.For the lentinan group,lentinan was prior injected and mitomycin was posterior injected.The side effects and clinical effect were observed and reported.Results The effective rate of Sapylin group was 85.3%,whereas 83.3%of lentinan group.There was no significant difference between the two groups(χ2 =0.051,P =0.822).Both groups had the following minor side effects:chest pain,fever,vomit and decreased white blood cells.No liver or renal injuries were reported.Conclusion The clinical outcomes of Sapylin combined with mitomycin and lentinan combined with mitomycin are both positive,in addition,the side effects are minor.
5.Application of functional imaging in diagnosis of diabetes mellitus
Zhemin HUANG ; Zhengwei ZHANG ; Chuantao ZUO ; Yihui GUAN
Chinese Journal of Endocrinology and Metabolism 2014;30(4):357-359
In either type 1 or type 2 diabetes,there is significant loss of β cell mass.Understanding the changing of β cell mass in the course of diabetes would provide important information for diagnosis and treatment.Functional imaging like magnetic resonance imaging or positron emission tomography (PET) can provide safe and noninvasive detection of loss of β cell mass in the course of diabetes.Among them,radio-labelled imaging is the most sensitive imaging procedure of the β cell ; For dihydrotetrabenazine PET imaging aiming β cell mass,there has been some primary outcome.For the key factor causing type 2 diabetes,18 F-6-deoxy-6-fluoro-D-glucose (18F-6-FDG) PET imaging is an effective tracer to study the glucose transporting condition in vivo.Further development of functional imaging will be of great value in diagnosis and treatment of diabetes.
6.Discussions on basic medical insurance management for those seeing doctors out of hometown in China
Qiuxiao CHEN ; Yihui SUN ; Zhigang YAO ; Yin ZHANG ; Zhong JIANG
Chinese Journal of Hospital Administration 2013;(2):81-83
A consensus remains unsettled yet for basic medical insurance and common protocols on managing patients seeing doctors out of their hometown.This results in such setbacks as difficulty in seeing doctors elsewhere for those covered and in unaffordable financial burden,as well as medical insurance fraud,lack of information sharing among social insurance authorities,and difficulty of supervision.This study described the status quo of seeding doctors elsewhere under China's basic medical insurance system,and analyzed problems found in the management framework.On such basis,authors proposed such recommendations as unified management system for seeding doctors elsewhere,network information sharing for medical insurance information,and networked settlement for medical expenses for basic medical insurance.These measures should be carried out as per general requirements for health reform stage by stage.
7.Parametric features of image textures in 18F-FDG PET/CT evaluation of lung nodules
Changmei WANG ; Yihui GUAN ; Wenqiang ZHANG ; Chuantao ZUO ; Fengchun HUA
Chinese Journal of Nuclear Medicine and Molecular Imaging 2013;(3):167-170
Objective To evaluate the parametric features of image textures on 18F-FDG PET/CT for the differentiation between malignant and benign pulmonary nodules and compare the diagnostic performance of these parameters with SUVmax.Methods 18F-FDG PET/CT images of 170 patients (102 males,68 females,age range:29-81 (mean 59)years) with pulmonary nodules were retrospectively evaluated.Eightynine pulmonary nodules (230 slices) were malignant and 81 (193 slices) were benign.The pulmonary nodules were contoured on CT images and mapped to the co-registered PET images.Thirteen parameters of textural features were extracted and SUVmax was measured.Logistic regression analysis was used to identify the significant texture parameters and create a regression model.The efficacy of the textural features and SUVmax to distinguish between malignant and benign pulmonary nodules was evaluated by ROC curve analysis.The textural features of squamous cell carcinoma and adenocarcinoma were compared via the Mann-Whitney u test.The sensitivity and specificity of the textural features and SUVmax for the differential diagnosis were compared with x2 test.Results Logistic regression model identified 4 textural features (skewness (β =1.7058),kurtosis (β =-1.0989),angular second moment (ASM,3 =-4.4140) and strength (β =0.5626) ; all P < 0.05) to have significant correlation with the malignancy of lung nodules.The AUC of ROC curve was 0.775 (95% CI0.732-0.819; P<0.001) with the sensitivity of 89.6% (206/230) and specificity of 50.8% (98/193).ASM and strength had statistically significant differences between squamous cell carcinoma and adenocarcinoma [ASM:0.0303 (95% CI 0.0392-0.0724) vs 0.0594 (95% CI 0.0721-0.0947) ; strength:2.4714 (95% CI 2.4632-4.1050) vs 1.5945 (95% CI 1.9003-2.4652) ; u =3082.0 and 3115.0,both P<0.01].The AUC of SUVmax-based diagnosis was 0.757 (95% CI 0.711-0.802 ; P < 0.001) with the sensitivity of 80.9 % (186/230) and specificity of 50.3 % (97/193) at a cut-off value of 2.5.The sensitivity of the textural features was superior to SUVmax in differentiating malignant from benign pulmonary nodules (x2 =6.903,P < 0.01).Conclusions Image textural parametric features extracted from 18 F-FDG PET/CT are more sensitive to differentiate between malignant and benign pulmonary nodules compared to SUVmax.They might also be useful to discriminate between different pathological types of lung cancers.
8.Variation of helper T cell 9/regular T cell balance in the inflammatory process of hepatitis B virus infection and its significance
Yihui LIU ; Yonghua ZHANG ; Li LIU ; Hongjuan ZHOU ; Hui FENG
Chinese Journal of Infectious Diseases 2013;31(11):646-649
Objective To observe the variation of helper T cell (Th)9/regular T cell (Treg cell) balance in the inflammatory process of hepatitis B virus (HBV) infection.Methods Two hundred patients with chronic HBV infection in Zhejiang Hospital of Integrated Traditional and Western Medicine during August 2011 to June 2012 were divided into four groups according to alanine aminotransferase (ALT) levels.:chronic HBV carriers,chronic hepatitis B (CHB) with mildly [upper limit of normal (ULN)<ALT<3 × ULN],moderately (3 × ULN<ALT<5 × ULN),or significantly (ALT>5 × ULN) elevated ALT,with 50 subjects in each group.In addition,30 healthy volunteers were enrolled as healthy controls (HC).ALT levels,HBV DNA,and Th9/Treg levels were measured by automatic biochemical analyzing equipment,real-time fluorescent quantitative polymerase chain reaction and flow cytometry,respectively.Th9/Treg levels of each group were observed.Means between groups were compared by t test,means of multiple groups were compared by one-way analysis of variance.Spearman rank correlation was used for correlation analysis.Results Age,sex distribution and HBV DNA levels of the four groups were comparable (P>0.05).ALT levels of HC were significantly different from those of mildly,moderately,or significantly elevated ALT (t=8.48,18.41,28.93; all P<0.05).Th9 cell levels,Treg cell levels and Th9/Treg ratio of HBV infected individuals were significantly different from those of HC (P<0.05).With the increasing degree of inflammation,proportion of Th9 cells increased and Treg cells decreased gradually.The differences among the four groups were of statistical significance (P< 0.05).Th9 cell level was positively correlated with ALT (r=0.804,P=0.01),while Treg cell level was negatively correlated with ALT (r=-0.828,P=0.01).Conclusions Th9/Treg is imbalanced in patients with HBV infection,and closely correlated with ALT levels.
9.AIDS Patient Associated with Penicilliosis marneffei and Differentiation with Other Diseases
Yihui YAO ; Xiaolu YU ; Qiuju WANG ; Genzhen SHAO ; Guoqiang ZHANG
Chinese Journal of Nosocomiology 2009;0(23):-
OBJECTIVE To report a case of AIDS associated with penicilliosis marneffei and discriminate the morphology in bone marrow examination and cultural characteristic of Histoplasma capsulatum and Leishmania donovani.METHODS The three pathogens in bone marrow morphology and cultural characteristic were studied.RESULTS AIDS patient was often infected with P.marneffei,but we could differentiated easily from other pathogens because of its breeding by splitting up and the characteristis structure in bone marrow examination.CONCLUSIONS Isolation of the P.marneffei is the golden diagnosis standard,and the examination of bone marrow is important to diagnose P.marneffei infection.
10.Study on Composition of Drug Property of Hot-natured Herb Euodiae Fructus
Yihui XIE ; Yutian ZHANG ; Jinrong LUO ; Liping HUANG
Chinese Journal of Information on Traditional Chinese Medicine 2014;(7):77-80
Objective To study the material basis of hot-natured herb Euodiae Fructus. Methods Euodiae Fructus extract was separated into the chloroform fraction, ethyl acetate fraction, n-butanol fraction and water fraction. With cold syndrome rat model by reserpine, the study confirmed that n-butanol fraction of Euodiae Fructus has influence on energy metabolism in rats. With the modified magnetic polymer microspheres, Euodiae Fructus n-butanol was divided into alkaloids, phenolic acid, fat soluble and water-soluble components, and the component of Euodiae Fructus influencing energy metabolism of model rats was further confirmed.Results The Euodiae Fructus extracts and alkaloids elevated rats temperature, reduced the Na+-K+-ATP activity, increased SDH activity, the content of ATP in liver tissue, the energy charge (EC) value and body heat production, and improve the level of energy metabolism.Conclusion The alkaloid is the material basis of hot-natured herb Euodiae Fructus.