1.Clinical study on 160 cases of herpes zoster treated by traditional Chinese medcine
Lidong ZHOU ; Bo LI ; Yihong ZHENG ; Yuejun SHI ; Shunpeng SONG ; Cheng ZHAN
International Journal of Traditional Chinese Medicine 2010;32(1):64-65
Objective To study the effects of treating herpes zoster with the combination of Chinese and western medicine.Methods 160 cases of herpes zoster were randomly recruited into a treatment group(n=80),and a control group (n=80).The control group was treated with westem medicine(acyclovir,ethacridine solvents,and vitamin B6 and B12).The treatment group was administrated with Chinese medicines,acupuncture and cupping on the basis of treats in the control group Results The total effective rate was 100%in the treatment group and 72.5%in the control group.There was significant difference between the two groups(χ~2=23.85,P<0.05).Conclusion The combination of Chinese and western medicine is effective in treating herpes zoster and worthy of generalization.
2.Effect of Zhuanggu Granula medicated serum on proliferation and differentiation of rabbit bone marrow stromal cells in vitro
Dexi CHEN ; Xiuyang WAN ; Yihong LI ; Jixiao LANG ; Guohu JIANG ; Wenxian HU ; Jinhua ZHAN ; Qiuxia LIU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(04):-
Objective: To investigate effect of Zhuanggu Granula medicated serum on proliferation and differentiation of bone marrow stromal cells(BMSCs) in vitro. Methods: Isolated BMSCs were cultured in vitro. The cells were treated with Zhuanggu Granula medicated serum, and the blank serum as the control group. The proliferation of cells was detected by MTT assay, the macroscopic histology, HE staining and immunohistoc-hemical examinations. Results: Zhuanggu Granula medicated serum effectively stimulated BMSCs proliferation (P
3.Combination of internal and external use of Chinese material medica with syndrome differentiation in treating 200 cases of acne vulgaris
Yuejun SHI ; Bo LI ; Yihong ZHENG ; Shunpeng SONG ; Cheng ZHAN ; Yinghua ZHU ; Qiao LI
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
Objective:To observe the effect of internal and external use of Chinese material medica with syndrome differentiation on acne vulgaris.Methods:200 patients with acne vulgaris were randomly divided into treatment group(110 cases)and control group(90 cases).Treatment group were given acne facial mask,oral medicine decoction,and the control group were treated with13-cis-Retinoic Acid Capsules,topical Clindamycin Gel,7 weeks for a course of treatment,the clinical effect were compared.Results:The effect on facial lesion in treatment group and control group had significant difference(P
4.Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): Chinese subgroup analysis.
Jiafu JI ; Han LIANG ; Youqing ZHAN ; Yunpeng LIU ; Yulong HE ; Yingjiang YE ; Yihong SUN ; Changming HUANG ; Ming YAN ; Yingqiang SHI ; Aiwen WU
Chinese Journal of Gastrointestinal Surgery 2014;17(2):133-138
OBJECTIVETo evaluate the efficacy and safety profile of XELOX (capecitabine/oxaliplatin) in patients with locally advanced gastric cancer who underwent curative D2 resection in China.
METHODSThis is a subgroup analysis of Chinese patients in the capecitabine and oxaliplatin adjuvant study in stomach cancer (CLASSIC study), which was a randomised, open-label, multicentre, parallel-group, phase III( study in the Asia-Pacific region. A total of 100 gastric cancer patients who received curative D2 gastrectomy were enrolled in this study and were randomly assigned to either XELOX group (oral capecitabine combined with intravenous oxaliplatin chemotherapy) or the control group (surgery alone). This study aims to compare the 3-year disease-free between the two groups.
RESULTSSubgroup analysis showed that 3-year DFS rate were 78% and 56% in XELOX and control group, respectively. The risk of relapse in XELOX group was reduced by 59% (HR=0.41, 95%CI:0.20-0.85, P=0.013), compared with the control group. The 3-year overall survival rate were 78% and 66% in XELOX and control group, with no statistically significant difference (HR=0.55, 95%CI:0.26-1.16, P=0.110).
CONCLUSIONAdjuvant XELOX chemotherapy following D2 gastrectomy may improve the survival in patients with advanced gastric cancer in China.
Antineoplastic Combined Chemotherapy Protocols ; therapeutic use ; Capecitabine ; Chemotherapy, Adjuvant ; Deoxycytidine ; administration & dosage ; analogs & derivatives ; Disease-Free Survival ; Fluorouracil ; administration & dosage ; analogs & derivatives ; Gastrectomy ; Humans ; Neoplasm Recurrence, Local ; Organoplatinum Compounds ; administration & dosage ; Stomach Neoplasms ; drug therapy ; surgery ; Survival Rate
5.Encephalomyelitis as the first manifestation of scrub typhus
Chen Wang ; Naian Xiao ; Yihong Zhan ; Qilin Ma
Neurology Asia 2019;24(2):157-159
Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. We report here a middle-aged
man with 3 days history of mild fever, dysphagia, and anarthria. On examination, he had nystagmus,
quadriparesis, and a fresh eschar in the left scrotal region. Cerebrospinal fluid (CSF) and serum
samples were positive for tsutsugamushi antibody. The magnetic resonance images (MRIs) showed
T2 lesions in the brainstem, basal ganglia, frontal, corona radiate and spinal cord. After treatment with
chloramphenicol and prednisolone, the clinical symptoms and signs improved. Our case highlights
that encephalomyelitis may be caused by rickettsial disease such as scrub typhus.