NM2 3genewasconsideredasatumormetastasissuppressor,itisalsoinvolvedintumor pathogenesis ,therearemoredetailedstudiesinbreastcarcinoma .Thisreviewfocusesontherelationshipbe tweenNM2 3geneandthemetastasisinbreastcarcinoma .

A Review Angiogenesis plays a key role in progression of prostate cancer. Antigiogenesis becomes a new treament target for prastate cancer. In this review, we focus on the current knowledge of angiogenesis and tumor angiogenesis inhibitor in prastate cancer. [

Thymus, lymph node and intestine (two pieces each) were taken from 20 adult guinea pigs and 10 adult rats. One piece was frozen in liquid nitrogen (-70℃) and cryostat sections were stained with Janszen and Nugteren (1971) method to demonstrate prostaglandin synthetase activity, Another piece was fixed in methanol, and paraffin sections were stained with HE and toluidin blue to demonstrate mast cell. Teased preparation of mesentery were stained by the same methods to show enzyme activity. Indomethacin inhibiting test was used as control. It is proven that the brown deposit represented the prostaglandin synthetase activity. These deposit existed in cytoplasm of mast cell, while and was absent in nucleus and specific granules. Prostaglandin synthetase positive mast cells distributed widely in lamina propria, axis of villi and submucosal layer in intestine, capsule, septa and medulla in thymus; capsule, trabecullum and paracortical zone of lymph node.

Enzyme linked lectin assay (ELLA) and lectin cytochemical staining are employed to study of WGA receptor on human sperm membrane of 44 fertile and 40 unexplained infertile males in this experiment. Binding capacity of sperm from fertile and infertile males, on the average, showed 16.3?10~7 and 9.39?10~7 WGA-HRP molecules per sperm, respectively (P

AIM: To explore the cellular mechanisms by which GLP-1(7-36)NH 2 stimulates insulin secretion in ?-cells. METHODS: Using adherent cell analysis and sorting cytometer (ACAS) by DiBAC 4(3) as a probe,effects of glucagon-like peptide-1(7-36)NH 2 on membrane potential was investigated in cultured neonatal rat pancreatic islet ?-cells,and radio immunological methods were used to determine the amount of insulin secretion in different glucose concentrations. RESULTS: In the presence of 2.8 mmol/L glucose,GLP-1(7-36)NH 2 could not increase insulin secretion and could not change membrane potentials of ?-cells;In the presence of 5.6,16.7 mmol/L glucose,GLP-1(7-36)NH 2 produced a marked increase in insulin secretion and enhanced the depolarization of ?-cells.In 16.7 mmol/L glucose, EGTA or nifedipine completely blocked GLP-1(7-36)NH 2-induced insulin secretion and changes in membrane potentials of ?-cells. CONCLUSION: GLP-1(7-36)NH 2 stimulates insulin secretion in a glucose concentration-dependent manner,it can enhance the depolarization of ?-cells caused by glucose.

Objective To evaluate the effect of shielding at the outside of radiation field by measuring the dose absorbed by the tissue outside the field in radiation therapy.Methods The dose absorbed by the tissue at 1cm offset the field was measured ofter setting radiation field and dose.The dose was measured again with shielding at the outside of radiation field in same field size and with the same prescription dose for comparison.Results The doses with or without shielding had distinct differences(P

(man and ram)The interstitial tissue was assessed by both parameters:(A″—A′)/N:ratio of interstitial tissue area and the number of seminiferous tubules;(A″—A′)/A′:ratio of interstitial tissue area and the total cellular area of seminiferous tubules.There is also a siginificant difference between various species for these parameters: the value of guinea pig is the smallest, while the value of swine is the largest.It was proved that the value of (A″—A′)/N of every species is closely related to the value of (A″—A′)/A′, and eight linear regressional equations were established. All these results have provided important data for further study of male reproductive physiology and male contraception research.

Bronchopulmonary dysplasia (BPD)characterized as the abnormal development of premature lung and trachea influenced by perinatal factors is the most common respiratory disease in very premature infants,and is also one of the diseases confirmedly related to poor quality of life.With the advancement of neonatal research and the im-provement in clinical care,more very premature infants with BPD survived to discharge.BPD is becoming the disease which both neonatologists and pediatricians should pay much attention to.The definition of BPD in recent years is in controversy.In this paper,the physiologic definition of BPD was comprehensively reviewed as a recently more accepted definition.

nm-23 gene is the first antimetastatic gene which was found to have close relationship with metastasis and prognosis of many malignant carcinoma.This review briefly summarizes the development of nm-23 gene and hepatocellular carcinoma in recent years.

Objective To treat urinary calculi with pneumatic lithotripsy under non-endoscopy.Methodes We applied the pneumatic lithotripsy machine,which made in China,to treat huge or staghom nephrolith and calculi of anterior urethra under non-endoscopy,taken out stone fragmentations after lithotripsy.There was 1 case of huge nephrolith,7cases of staghom nephrolith,3 cases of anterior urethral calculi.Results Every case of nephrolith was successfully performed by using lithotrisy and extracted stones only one case.1 case in total nephrolith cases was found residual stones and sick-side renal functions were improved than before in all casws followed up for 3 moths to 2 years.the cases of anterior urethral calculi urinated fluently and had no urethral stenoses followed up 1～2 years.Conclusion This kind of operation used pneumatic lithotripsy to treat urinary calculi under non-endoscopy is safe,slight injury and curative effect is reliable.