1.Relationship between high plasma C-reactive protein and outcome in patients with acute cerebral hemorrhage
Yifan ZHANG ; Jianhua YANG ; Zhonglei ZHANG
Journal of Clinical Neurology 1995;0(04):-
Objective To study the relationship between the plasma levels of C-reactive protein (CRP) and the severity of disease as well as outcome in patients with cerebral hemorrhage at early stage. Methods The CRP plasma levels were measured by scatter turbidimetry in 89 patients with cerebral hemorrhage within 24 hrs after onset of the disease. The control group included 30 healthy people who received medical examinations. We analyzed the relationship between CRP levels and the severity of disease as well as outcome.Results CRP levels were less than 8 mg/L (4.21?1.78 mg/L) in control group, and increased in 51 patients with cerebral hemorrhage (30.33?2.53 mg/L), with an abnormal rate of 57.30%. CRP levels and abnormal rate differed significantly (all P
2.Study on the Quality Standard for Xiaobai Capsules
Jialong LIANG ; Yifan YANG ; Dongxu ZHANG ; Huiwen JING ; Yukun WANG
China Pharmacist 2015;(8):1309-1312
To establish the quality standard for Xiaobai capsules. Methods: Paeoniae Radix Alba and Angelicae Sinensis Radix were identified by TLC. The contents of psoralen and isopsoralen were determined by HPLC. Results:The qualitative i-dentification was with high resolution and without interference from the negative substances. The linear range of psoralen was 1. 082-108. 200 μg·ml-1 . The average recovery was 99. 82% with RSD of 1. 16%. The linear range of isopsoralen was 0. 818-81. 800μg· ml-1 . The average recovery was 99. 85% with RSD of 1. 81%. Conclusion:The method can be used in the quality control of Xiaobai capsules.
3.Study on the Assessment Indicator System of the Accessibility of Essential Medicines
Binchi LIAO ; Ming HU ; Naitong ZHOU ; Nan YANG ; Yifan HUANG
China Pharmacy 2016;27(18):2449-2451
OBJECTIVE:To explore the assessment indicators of the accessibility of essential medicines to comprehensively evaluate the accessibility of essential medicinesand its coverage of medicine supply security and service quality and the improve-ment of the implementation of the new Healthcare reform. METHODS:Retrieved from Chinese and English Literature and the World Health Organization(WHO),theoretical analysis was conducted for the covering the core elements of essential medicines to explore construction ideas and content of essential medicines evaluation index system with international suitability,index appropri-ateness and operability. RESULTS&CONCLUSIONS:A series of medicine policy evaluation guide established by WHO is current-ly the main basis of the accessibility of essential medicines evaluation around the world,however,there are certain limitations for these indicators.According to the concept put forward by WHO and the related organizations,the core elements of the accessibility of essential medicines include:availability,affordability,supply system,sustainable financing,medicine quality and appropriate use.
4.Efficacy of mid-axillary approach to transversus abdominis plane block in each abdominal and back region
Jianfeng MA ; Yifan PAN ; Jianping YANG ; Zuokai XIE ; Jun LI
Chinese Journal of Anesthesiology 2016;36(10):1247-1249
Objective To evaluate the efficacy of mid-axillary approach to transversus abdominis plane (TAP) block in each abdoninal and back region.Methods Twenty patients of both sexes,aged 18-64 yr,with body mass index of 20-27 kg/m2,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,scheduled for elective laparoscopic cholecystectomy,who had expected operation time <1 h,were enrolled in the study.Ultrasound-guided TAP block was performed on the left side via the mid-axillary line with 0.25% levobupivacaine 0.5 ml/kg.TAP block was assessed by cold stimulation (75% alcohol) and acupuncture in each abdominal and back region (the left side of the body was divided into 19 regions using the anatomical landmarks on the body surface).The positive condition in each region at 20 min after administration was recorded.Results The regions in which the positive rate ≤5% were 11,14,17 and 18 regions.The regions in which the positive rate >5%-20% were 8,15 and 19 regions.The regions in which the positive rate >20%-50% were 12,13 and 16 regions.The regions in which the positive rate >50%-70% were 1 and 4 regions.The regions in which 70% < the positive rate < 95% were 7,9 and 10 regions.The regions in which the positive rate ≥ 95% were 2,3,5 and 6 regions.Conclusion Mid-axillary approach to TAP block is effective in the left middle-lower regions of the anterior abdominal wall,however,it is ineffective in the left upper region between mid-axillary and posterior axillary lines and in the low back region.
5.Effect of Total Flavonoids from Alpinia officinarum on Gastrointestinal Motility
Yanfen CHEN ; Tao JIANG ; Chunping TANG ; Yifan FENG ; Chaoyan YANG
China Pharmacy 2005;0(23):-
OBJECTIVE: To study the effect of total flavonoids from Alpinia officinarum on gastrointestinal motility.METHODS: Gastric emptying method was applied to observe the effect of total flavonoids from A.officinarum on gastric emptying of normal mice and sthenic gastric emptying induced by pyridostigmine bromide.Effect of total flavonoids from A.officinarum on gastric smooth muscle of rats was observed through in vitro test and small intestine advancement was used to observe the influence of total flavonoids from A.officinarum on intestinal motility.RESULTS: Total flavonoids from A.officinarum had no significant influence on gastric emptying of normal mice,but distinctly inhibited sthenic gastric emptying induced by pyridostigmine bromide(P
6.Comparison of three-dimensional position on cone beam computed tomography of temporomandibular joint osteoarthrosis.
Xiaomin LI ; Xiaoyu YANG ; Yifan CHEN ; Lijie BAO
West China Journal of Stomatology 2015;33(2):161-165
OBJECTIVEThis study investigates the effect of temporomandibular joint osteoarthritis (TMJOA) on different stages of condylar three-dimensional position and provides a theoretical basis for clinical application.
METHODSThe cone beam computed tomography (CBCT) images of 108 TMJOA patients were analyzed and divided into four stages based on the stage standard of osteoarthrosis X-ray performance proposed by Xuchen Ma in 2005. A total of 28 defect-free temporomandibular joint disorders were used as the control group. Differences in condylar position and condylar axis horizontal angle were evaluated and compared.
RESULTSNo significant differences were found in terms of sagittal relationship, but condylar axis horizontal angle showed a significant difference (F = 3.872, P = 0.005). The horizontal angle values of stage 1 in the TMJOA group were lower than those in stages 2 and 3 (P = 0.027, P = 0.000), whereas the horizontal angle values of stage 2 and control groups were lower than those of stage 3 group (P = 0.004, P = 0.047).
CONCLUSIONCondylar horizontal angle differed in each stage of TMJOA, but no significant difference between the parasagittal positions of the condyles was observed in each stage.
Case-Control Studies ; Cone-Beam Computed Tomography ; Humans ; Mandibular Condyle ; Osteoarthritis ; diagnostic imaging ; Temporomandibular Joint ; diagnostic imaging ; pathology ; Temporomandibular Joint Disorders ; diagnostic imaging
7.Current situation and analysis of clinical application of auricular acupoint sticking therapy
Yanting YANG ; Qinfeng HUANG ; Yifan JIA ; Jie LIU ; Xiaopeng MA
Journal of Acupuncture and Tuina Science 2016;14(2):141-148
Objective: By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of diseases and effective rates of various diseases, in order to objectively reflect the general situation of clinical application of ear point embedding method in the recent years. Methods: By the bibliometrical analysis, the literature on auricular acupoint sticking in the recent ten years was counted up, analyzed and categorized. Results and Conclusion: Auricular acupoint sticking is used clinically for diseases of 16 systems, including 130 diseases. 74 diseases were singularly treated with auricular acupoint sticking, including the advantageous disease category like insomnia, constipation and obesity, and secondary advantageous disease category like dysmenorrhea, myopia, allergic rhinitis, post-operative pain and acne vulgaris.
8.Discussion on pathology experimental teaching reform of medical undergraduate students
Huimin YANG ; Xin LIU ; Yifan HUANG ; Zumao LI
Chinese Journal of Medical Education Research 2014;13(11):1126-1128
The traditional experimental teaching of pathology has defect in training the students' operating ability and mobilizing the initiative of students to observe.Pathology Department of North Sichuan Medical College has developed pathology specimens-making competition for undergraduate students.The students observed,chose and made specimens by themselves after sufficient review of the relevant pathology knowledge.The competition has mobilized the enthusiasm of students effectively and developed their operating ability.This form of teaching should become beneficial supplement to the experimental teaching of pathology.
9.Study on ‘ problem behavior' and influencing factors during job hunting of medical students
Xi YANG ; Li KANG ; Yifan XIAO ; Ruifen SHI
Chinese Journal of Medical Education Research 2013;(1):71-74
Objective To understand the ‘ problem behavior' and influencing factors during job haunting of medical students and to provide guidance for students.Methods Totally 409 medical students who had graduated or were going to graduate but all having the experiences of applying for jobs were surveyed with self-made questionnaire.Likert 5 points scoring method was employed to evaluate the job hunting and SPSS 17.0 seftware was used to do statistical analysis.Results The ‘ problem behaviors' with the highest scores were conformism and comparison [(3.93 ± 0.628) and (3.80 ± 0.847) respectively)].Self factors influencing students' behavior in career choice included the capacity for self-definition (3.62 ± 0.855),personal values (3.55 ± 0.893) and legal awareness (3.51 ± 1.039).Meanwhile,the factor with the highest score was education cost (3.93 ± 0.887).Besides,influences of family expectation (3.43 ± 0.945),employment environment (3.40 ± 0.940) and college educational system (3.28 ± 1.038) were also outstanding.Conclusions Medical students'‘ problem behaviors' during job hunting are diverse and are influenced by many factors.So,we are supposed to strengthen the education and guidance from the self factors,combining the actions of school,family and society to promote medical students' employment.
10.Study on Quality Standard for the Leaves of Nauclea officinalis
Xiaoqiang ZHANG ; Yun WU ; Yifan YANG ; Zhenzhong WANG ; Gang DING
China Pharmacy 2017;28(15):2097-2100
OBJECTIVE:To establish the quality standard for the leaves of Nauclea officinalis. METHODS:Microscopic identi-fication and TLC methods were used for qualitative identification of N. officinalis. The moisture and ash of medicinal materials were determined. HPLC method was adopted to determine the content of strictosamide in medicinal materials. The determination was per-formed on Lichrospher C18 column with mobile phase consisted of acetonitrile-0.1% phosphoric acid solution(gradient elution)at the flow rate of 1 mL/min,injection volume was 10 μL. The detection wavelength was set at 226 nm,and the column temperature was 30 ℃. RESULTS:Microscopic identification of the leaves of N. officinalis had strong characteristics,and TLC sports were clear and well-separated without interference from negative control. The linear range of strictosamide were 0.0105-0.21 mg/mL(r=0.9995);RSDs of precision,stability and reproducibility tests were all lower than 2.0%. Average recoveries were 96.25-101.82%(RSD=1.86%,n=9). Total ash of medicinal materials was 5.27%-6.44%,acid insoluble ash was 0.23%-0.36%,water content was 9.48%-11.46%,strictosamide was 0.124%-1.003%. CONCLUSIONS:Established standard can be used for quality evaluation of N. officinalis.