Objective To probe into possibilities and sensitivity of CCD video camera system in the assessment of balance function.Methods The system is composed of a CCD video camera,a video image capture board and analysis software.Three indexes:Trunks,ayAngle (TSS Trunk Sway Speed(TSS) and fall index (FI).the normal group:FI≥I; mild group:0.7≤FI＜I; moderate group:0.4≤FI＜0.7; severe group:FI ＜0.4.Disorder of balance function group:42 patients with cerebrovascular accident,mean age of (67.4±8.0) years.Control group:42 healthy subjects,mean age of (65.3±6.5) years.All cases were measured by Berg balance scale and determinated three times by CCD video camera system with eye opening (eo) and eye closing(ec),and averaged.Results There were very significant differences in TSAeo,TSAec,TSSeo,TSSec,FIeo,FIec between disorder of balance function group and control group (P＜0.01).as well as Berg balance scale (P＜0.05).In disorder of balance function group,the differences among three groups were significant in TSAeo,TSAec,TSSeo,TSSec (P＜0.05).There were significant differences in TSAeo,TSAec,TSSeo,TSSec between severe group and mild group (P＜0.01) as well as in Berg balance scale (P＜0.05).Conclusions CCD video camera system has a higher sensitivity in assessment of body,balance than Berg balance sca land great value in clinical application.

Objective To detect the expression of COX-2 and p53 in breast carcinoma tissue and investigate their associations with clinical prognosis.Methods The expression of COX-2 and p53 was carried out in 16 cases of normal epithelial tissue and 152 cases of breast carcinoma tissue using immunohistochemistry SP method.The correlation of their expression with clinical characteristics was analyzed using SPSS software 16.0.Survival analysis was used to investigate their effects on tumor prognosis.Results No positive COX-2and p53 expressions were observed in normal epithelial tissue.Among 152 patients,89 (58.6 ％) were positive staining rete for COX-2 and 93 (61.18 ％)were shown p53 expression, with a statistically significant associations between expressions of COX-2 and p53 and breast cancer (r =0.426,P ＜ 0.01).The COX-2 and p53 expressions were significantly correlated with pathological grade, clinical stage, lymph node or distant organ metastasis.There was a statistically significant correlation between COX-2 and p53 expression and pathological grade Ⅰ / Ⅱ.The 5-year progress-free survival (PFS) rate in patients with COX-2 over-expression was 61.3 ％, which was remarkably lower than that in those with low COX-2 expression.There was no statistically significant difference of 5-year PFS between positive and negative p53 expression.A shorter 5-year PFS was seen in patients with co-expression of COX-2 and p53 than in those with either COX-2 or p53positive expression alone and also than in those with both COX-2 and p53 negative expression.Conclusion Detection of the expressions of COX-2 and p53 can be used to predict the prognosis of breast cancer.

Pancreaticobiliary maljunction means the common bile duct and the main pancreatic duct in the duodenal wall, or is the formation of a long common channel leading to biliopancreatic reflux, resulting a series of biliopancreatic diseases, and even the occurrence of biliary malignancy. The pathogenesis of pancreaticobiliary maljunction is complex, involving biliary fluid dynamics, the activation of phospholipase A2, protease activation, amino acids, fat metabolism, gene mutation. This paper summarized the latest study of the pathogenesis of the pancreaticobiliary maljunction to let clinicians understand pancreaticobiliary maljunction diseases, and provide new treatment ideas.