1.Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute.
Haiyong CHEN ; Yibin FENG ; Lixing LAO
Journal of Integrative Medicine 2014;12(3):187-90
To meet community demands with optimal Chinese and conventional medical treatment, the University of Hong Kong is promoting integrative medicine by developing Chinese medicine programmes that train students of both Western and Chinese medicine. The programmes emphasize multi-disciplinary training and interaction between the two therapeutic approaches, enabling students to establish reliable, consistent, and respectful mutual cooperation in their future careers.
2.The distinguishing reaction of nitrate and nitrite in Dantong Tablets
Yibin CHEN ; Jaxi CHEN ; Yu FENG ; Minggeng WANG
Chinese Traditional Patent Medicine 1992;0(08):-
AIM: We establish a suitable distinguishing reaction of nitrate and nitrite in Chinese traditional medicine containing reduction agents. METHODS: In different concentration solution of sulfate acid,we study on the distinguishing reaction,by paralleling samples with negative samples and positive samples. RESULTS:The nitrite and sample containing nitrite react with ferrous sulfate reagent from brown in 50%-5% solution of sulfate acid;The nitrate and sample containing nitrate react with ferrous sulfate reagent from brown in ≥25% solution of sulfate acid.The negative sample and sample without nitrite and nitrate does not react with ferrous sulfate reagent in 50%-5% solution of sulfate acid. CONCLUSION: The thin sulfate acid-ferrous sulfate reagent-nitrate ditinguishing reaction can be used to distinguish nitrate and nitrite in Chinese traditional medicine containing reduction agents.
3.Exploration and Practice on Teaching Mode of Clinical Practice for the Speciality of Laboratory Medicine
Wenli FENG ; Zhiguang TU ; Yibin YIN ; Hongchu CHEN ; Gefei KANG
Chinese Journal of Medical Education Research 2003;0(02):-
According to the characteristics of the Laboratory Medicine and our twenty years' medical educational experience ,we explore to improve the quality of education and cultivate the students' practical ability and creative ability. And we construct an educational mode for clinical practice, laboratory medical practice and research project.
4.Construction of national key disciplines and innovative of post-graduate education
Wenli FENG ; Yibin YIN ; Zhiguang TU ; Yaguang WENG ; Jianjun ZHU
Chinese Journal of Medical Education Research 2006;0(07):-
This paper summarizes that to strengthen the construction of national key disciplines Clinical Laboratory Diagnostic and build professional post-graduate education platform for innovation,the exploration and practice of reform have been done in Chongqing Medical University,in the teaching ranks and exercise disciplinary research direction to enhance the level of scientific research and laboratory construction.
5.Three-dimensional finite element study on the change of glossopharyngeum in patient with obstructive sleep apnea hypopnea syndrome during titrated mandible advancement.
Suixing YANG ; Jing FENG ; Zuo ZHANG ; Aili QU ; Miao GONG ; Jie TANG ; Junheng FAN ; Songqing LI ; Yanling ZHAO
West China Journal of Stomatology 2013;31(2):150-157
OBJECTIVETo construct a three-dimensional finite element model of the upper airway and adjacent structure of an obstructive sleep apnea hypopnea syndrome (OSAHS) patient for biomechanical analysis. And to study the influence of glossopharyngeum of an OSAHS patient with three-dimensional finite element model during titrated mandible advancement.
METHODSDICOM format image information of an OSAHS patient's upper airway was obtained by thin-section CT scanning and digital image processing were utilized to construct a three-dimensional finite element model by Mimics 10.0, Imageware 10.0 and Ansys software. The changes and the law of glossopharyngeum were observed by biomechanics and morphology after loading with titrated mandible advancement.
RESULTSA three-dimensional finite element model of the adjacent upper airway structure of OSAHS was established successfully. After loading, the transverse diameter of epiglottis tip of glossopharyngeum increased significantly, although the sagittal diameter decreased correspondingly. The principal stress was mainly distributed in anterior wall of the upper airway. The location of principal stress concentration did not change significantly with the increasing of distance. The stress of glossopharyngeum increased during titrated mandible advancement.
CONCLUSIONA more precise three-dimensional finite model of upper airway and adjacent structure of an OSAHS patient is established and improved efficiency by Mimics, Imageware and Ansys software. The glossopharyngeum of finite element model of OSAHS is analyzed by titrated mandible advancement and can effectively show the relationship between mandible advancement and the glossopharyngeum.
Finite Element Analysis ; Humans ; Mandible ; Sleep Apnea, Obstructive ; Tomography, X-Ray Computed
6.Effects of Dengzhanhua Capsule on Kidney Tissue Inflammatory Cytokines in Chronic Renal Failure Rats
Yibin DU ; Xiao WU ; Feng WU ; Qi LI ; Kunyang ZHANG ; Yanrui DUAN ; Chuqiao XIE ; Liqun HE
Chinese Journal of Information on Traditional Chinese Medicine 2014;(12):63-65
Objective To observe the effects of Dengzhanhua Capsule on kidney tissue inflammatory cytokines in chronic renal failure rats;To explore its possible mechanism for the efficacy in chronic renal failure. Methods Sixty SD rats were randomly divided into normal control group, model group, benazepril group and Dengzhanhua group, 15 rats in each group. Chronic renal failure rat model was established by Platt 5/6 nephrectomized. Benazepril (0.29 mg/100 g) was given to rats in the benazepril group by gastrogavage. Dengzhanhua Capsule (0.3 g/100 g) was given to rats in the Dengzhanhua group by gastrogavage. Normal saline was given to rats in the normal group and the model group by gastrogavage. The whole treatment period was twelve weeks. Expressions of TGF-β1 and PAI-1 were determined by semi-quantitative RT-PCR after treatment. Concentrations of kidney tissue inflammatory cytokines IL-6 and TNF-α were determined by ELISA. Results Expressions of TGF-β, PAI-1 and IL-6, TNF-αin benazepril group and Dengzhanhua group were significantly lower than those in model group (P<0.05). Compared with benazepril group, it was significantly lower in Dengzhanhua group (P<0.05). Conclusion Dengzhanhua Capsule can reduce kidney tissue inflammatory in chronic renal failure rats, and inhibit renal fibrosis.
7.A Method of Qualitative and Quantitative Analysis on Fluid Catalytic Cracking Full Range Gasoline by Comprehensive Two-Dimensional Gas Chromatography Coupled with Time-of-Flight Mass Spectrometry
Li XIN ; Chaohe YANG ; Xiang FENG ; Yibin LIU ; Xiaobo CHEN ; Honghong SHAN
Chinese Journal of Analytical Chemistry 2017;45(4):489-494
A method of qualitative and quantitative analysis on fluid catalytic cracking (FCC) full range gasoline by comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC×GC-TOF MS) was established. The results showed that paraffins, olefins, naphthenes and aromatics in FCC gasoline had regional and zonal distribution in two-dimensional contour plots. The distinctions of boiling points and polarity between different compounds were used to achieve the accurate separation and determination in GC×GC-TOF MS analysis, and consequently the co-current flow which was often present in the conventional GC analysis was greatly suppressed. The difference of ionizing efficiency between different compounds was modified by response factors, and moreover, a good quantitative dependency was found between the analysis results of GC and GC×GC-TOF MS on FCC gasoline. Due to the high separation resolution, GC×GC-TOF MS gave more accurate results about the group compositions of FCC gasoline. GC×GC-TOF MS provided an effective way with high precision for the characterization of FCC gasoline.
8.Effect analysis of embolization device for the treatment of large or giant intracranial aneurysms
Mingtao FENG ; Wei CAO ; Jia'nan LI ; Pengfei YANG ; Yibin FANG ; Yi XU ; Bo HONG ; Qinghai HUANG ; Jianmin LIU
Chinese Journal of Cerebrovascular Diseases 2017;14(1):32-36
Objective To evaluate the safety and effectiveness of Pipeline embolization device (PED) for the treatment of large and giant intracranial aneurysms.Methods Frorn November 2014 to May 2016,the clinical and radiological data of 33 patients with intracranial aneurysm confirmed by DSA or head CT angiography (CTA) or head magnetic resonance angiography (MRA) at the Department of Neurosurgery,Changhai Hospital,the Second Military Medical University were enrolled retrospectively.Its safety and effectiveness were evaluated.Results The Pipelines were successfully released in 33 patients with 35 aneurysms,10 aneurysms were implanted by using PED alone,25 were implanted by using PED combined with coil embolization (including 2 were implanted by using Pipeline bridging technology).During the perioperative period,1 thrombotic event(one aneurysm) occurred and had hemorrhagic transformation.One(one aneurysm) died of fatal aneurysm delayed bleeding.Thirty-one patients (33 aneurysms) were followed up clinically,the follow-up time was 4-18 months,no bleeding or thrombosis events occurred.Eighteen aneurysms received a short-term postoperative imaging follow-up (3-5 months,enhanced MRA or DSA),of which 10 had neck residue or aneurysm development,and 8 aneurysms did not have development at all,and 19 achieved postoperative mid-term imaging follow-up (6-16 months,enhanced MRA or DSA).Two of them had neck residue and 17 did not develop at all.Conclusion Pipeline for the treatment of intracranial large and giant aneurysms may be safe and effective.However,the complications of intracranial hemorrhage cannot be ignored after implantation of embolization device.Its related mechanism needs to be further studied.
9.A preliminary study on the application of high-resolution magnetic resonance vessel wall imaging in the ;evaluation of intracranial aneurysms
Feng LIANG ; Tiewei QI ; Zhuhao LI ; Meng WANG ; Liqin WANG ; Fanying LI ; Yibin YANG ; Siqi OU ; Zhengsong HUANG
Chinese Journal of Nervous and Mental Diseases 2016;42(3):175-179
Objective The present study was to investigate the feasibility of use of high resolution magnetic reso?nance vessel wall imaging(HR-VWI)in evaluation of intracranial aneurysms. Methods We prospectively collected data from patients who had intracranial aneurysms and received HR-VWI scan before surgical treatment or conservative treatment. Aneurysms were divided into ruptured group (n=12) and unruptured group (n=88). Aneurysm site, size, neck, aspect ratio(AR), daughter sac and aneurysmal wall enhancement scale were analyzed in both groups. Univariate and multivariate Logistic regression were performed to evaluate the risk factors of aneurysm rupture. Subgroup analysis was also performed to study symptomatic and asymptomatic unruptured aneurysms. Results Aneurysm size(t=2.187,P=0.031),AR(t=3.164,P=0.002),incidence of daughter sac(P=0.012) and aneurysmal wall enhancement scale(P<0.001)were higher in ruptured aneurysm group. Multivariate Logistic regression showed that aneurysmal wall enhance?ment scale was the only independent risk factor of ruptured aneurysms(P=0.002). Subgroup analysis showed aneurysm wall enhancement scale(P<0.001) and AR(t=3.939,P<0.001) were higher in symptomatic unruptured aneurysms. Conclusion Aneurysm wall enhancement on HR-VWI is more frequently seen in ruptured aneurysms and symptomatic unruptured aneurysms. Histological study is needed for better understanding of the mechanism of aneurysm wall enhance?ment.
10.Clinicopathological characteristics and risk factors of lymph node metastasis in isthmus papillary thyroid microcarcinoma
Yun SUN ; Liang CHEN ; Yibin SHEN ; Yun FANG ; Feng ZHU ; Qinsheng ZHU ; Hedi TIAN ; Jiajun SHEN ; Yijun WU
Chinese Journal of Endocrine Surgery 2021;15(3):278-282
Objective:To investigate the clinicopathological characteristics of papillary thyroid microcarcinoma in the isthmus (PTMCI) and the independent risk factors of central lymph node metastasis.Methods:58 consecutive patients with PTMCI admitted from Jan. 2016 to Dec. 2018 (isthmus group) were retrospectively analyzed, including 15 males and 43 females,age (42.93±12.69) years old; According to the specific location of papillary thyroid microcarcinoma (PTMC) in isthmus, PTMCI were subdivided into the right PTMCI and the left PT-MCI 67 patients with a single PTMC located in the unilateral lobe were randomly selected as a control (lobe group) , including 13 cases of male and 54 cases of female, age (47.18±11.34) years old. Index included the patient’s age, gender, tumor diameter, TPOAb, aspect ratio, microcalcification, capsular invasion, lymph node metastasis, surgical methods, operation method, and scope of lymph node dissection. SPSS 21.0 software was used for statistical analysis. The quantitative data of normal distribution was expressed as ± s,and the difference between the two groups was compared by chi-square test.The risk factors of CLNM of the isthmus group were analyzed with univariate chi-square test and multivariate Logistic regression analysis.The difference was statistically significant if P<0.05. Results:Compared with PTMC, PTMCI showed a higher rate of capsule invasion ( P=0.003) ,lymph node metastasis ( P=0.049) ,lymph node metastasis in central region ( P=0.033) ,and surgical methods between the two groups were statistically significant ( P<0.05) ;But PTMCI was significantly lower than PTMC in aspect ratio>1 ( P<0.05) . Univariate analysis showed that capsule invasion ( P=0.001) and microcalcification ( P=0.012) were risk factors for PTMCI lymph node metastasis. Multivariate Logistic regression analysis showed that capsule invasion ( P=0.016) and microcalcification ( P=0.046) were independent risk factors for central lymph node metastasis in PTMCI. Conclusions:Compared with PTMC,PTMCI indicates a higher rate of capsular invasion,lymph node metastasis in prelaryngeal and central lymph node;Compared with PTMC, PTMCI indicates a lower rate of aspect ratio>1; Capsule invasion and microcalcification are independent risk factors for central lymph node metastasis in PTMCI. For patients with the right PTMCI or the left PTMCI and also without capsular invasion and calcification,ipsilateral central lymph node dissection should be considered.