Objective To study the technique of using the postauricular revolving door island flap in one-stage reconstruction of concha defect and its efficacy.Methods Fifteen cases of concha de fect were repaired by the postauricular revolving door island flap in one stage reconstruction from 2000-2010.The maximum size of defect was 2.7 cm× 3.0 cm,and the minimum was 1.0 cm×1.3 cm.Results All the island flaps were survived postoperatively,and satisfactory in auricular appearances of all patients by 6 months to 5 years follow-up.Conclusions The revolving door island flaps with abundant blood supply are transferred to reach the auricular defect,which match normal auricular tissue in contour,color,and texture. This flap on the retroauricular area is relatively concealed,and it therefore can be one of the best procedures for repair of the auricular defects,especially concha.

Complex regional pain syndrome (CRPS) is a neuropathic pain disorder, characterized by persistent and severe pain after trauma or surgery. Diagnosis is mainly based on clinical signs and treatment is based on a multidisciplinary approaches, including non-pharmacological approaches and occupational therapy，pharmacotherapy and invasive therapeutics. This article reviewed the current advice of diagnosis and treatment of CRPS.

BACKGROUND: Mineral trioxide aggregate (MTA) is a new inorganic trioxide polymer. Previous studies indicated that MTA as a root tip material had good edge closeness as compared to silver amalgam and vitreous enamel-cementum.OBJECTIVE: To study the effect of anti-micro-osmosis of metal dowel pins cemented by MTA.DESIGN: Comparative observational study.SETTING: Jingzhou Central Hospital of Hubei Province.MATERIALS: Thirty-two submaxilla first premolars which were pulled out by the orthodontic treatment in 2004 of the hospital were selected, of which teeth were intact, dental roots were stout, straight and unbroken. MTA was provided by Dentsply Co., USA; zinc phosphate cement by Shanghai Dentistry Material Station; glass ionomer cement by Shanghai Qingpu Dentistry Material Station; EB composite resin by the Fourth Military Medical University Oral Medical Hospital.METHODS: Having been filled by traditional technique, 32 fresh single-rooted permanent teeth were randomly divided into 4 groups and cemented in casting dowel pins separately with four cements-zinc phosphate cement, glass ionomer cement, EB composite resin and MTA groups with 8 in each group. And then the dye penetration method was used to test the micro-osmosis of these cements.MAIN OUTCOME MEASURES: Micro-osmosis of the four cements.RESULTS: MAT as a cement had the minimum micro-osmosis while zinc phosphate cement had the maximum osmosis. The depth of osmosis that ranked from minimum to maximum was MTA

HIV/AIDS has been circulating in China for over 25 year. While making progress and achievements on HIV/AIDS prevention, there still are great challenge and difficulties such as HIV epidemic controlling and vaccine research.

As the excellent country or region refers to medical insurance system , the United Kingdom , Singa-pore and Hong Kong are often the focus of international academic circles .However , the difference is that the United Kingdom is a model of free universal medical care , Singapore is a government-led mixed medical protection mode , and Hong Kong earns a worldwide reputation on health care by virtue of the high quality , low price public hospital services .This article assesses the advantages and limitations of the three medical insurance systems in terms of equity in financing , individual affordability, insurance coverage , sustainability in financing and individual responsibility , and provides a reference for health care reform in China .

Congenital long QT syndrome ( LQTS) is a cardiac ion channel dysfunction, leading to prolonged myocardial repolarization time. It is characterized by the typical ECG QT interval prolongation and torsades de pointes. It shows clinical recurrence of cardiogenic syncope and even lead to sudden death. Molecular genetic studies have revealed a total of 12 forms of congenital LQTS caused by mutations in genes of the potassium, sodium and calcium channels or membrane adapter located on chromosomes 3, 4, 7, 11, 12, 17, 20 and 21. This review summarized the studies of the pathogenesis of LQTS and gene-related treatments.

Duchenne muscular dystrophies is a deadly disease caused by genetic defect in the skeletal muscle system,and there is no complete cure so far.For a long time,the scholars at home and abroad have made unremitting efforts for its treatment research,and made some great progresses.This paper summarizes the related literatures in recent years.The Duchenne muscular dystrophy treatment methods and progresses are reviewed in this review.

Objective To compare the clinical effects of bisoprolol and metoprolol in treatment patients with chronic heart failure (CHF).Methods 126 patients with CHF were randomly divided into two groups,63 cases in each group.And two groups were treated with bisoprolol or metoprolol based on the conventional anti-HF treatment.The clinical effects of the two groups were compared.Results The total effective rate of the bisoprolol group was 92.1％ (58/63),which was significantly higher than 79.4％ (50/63)in the metoprolol group(P ＜0.05).The HR,SBP,DBP,and LVEF were significantly improved in the two groups after the treatment(P ＜ 0.01).SBP (98.7 ±13.7) mm Hg,LVEF (48.6 ± 7.7)％ in the bisoprolol group were significantly better than (102.5-± 13.8)mm Hg and (45.4 ± 7.9)％ in the metoprolol group after treatment(P ＜ 0.05).But there was no significant difference in the incidence rate of clinical adverse events between the two groups (P ＞ 0.05).Conclusion Bisoprolol and metoprolol can effectively improve the heart function of patients with CHF,but bisoprolol has more advantages,so we should strictly control the indications in the clinical work,to make a reasonable choice of drugs.

Objective To investigate the effect and significance of minimally invasive removal of intracranial hematoma on the blood-brain barrier in patients with intracerebral hemorrhage (ICH).Methods Clinical data of 20 patients with ICH were randomly selected and received minimally invasive surgery (operative group) and 20 patients with ICH received expectant treatment therapy (expectant treatment group) were analyzed retrospectively,and 20 healthy people were randomly collected for control group.The blood-brain barrier (BBB) and serum myelin basic protein (MBP) concentration were analyzed.Results The BBB index of the iperative group was 0.0075 ± 0.0007,the expectant treatment group was 0.0083 ± 0.0006 and the control group was 0.0068 ± 0.0004.The BBB index in the operative group was significantly lower than that in the expectant treatment group (P ＜ 0.05),and the BBB index in these two groups was significantly higher than that in the control group (P＜ 0.01).The serum MBP concentration in the operative group was (3.29 ± 1.55) μg/L,the expectant treatment group was (6.55 ± 3.78) μg/L,and the control group was (1.12 ± 0.48) μ g/L.The serum MBP concentration in the operative group was significantly lower than that in the expectant treatment group (P ＜ 0.05),and these two groups were significantly higher than the control group (P ＜ 0.01).Conclusions The permeability of BBB in patients with ICH are increased,the BBB index and the serum MBP concentration in patients with ICH are increased,minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema.

Childhood asthma is one of type Ⅰ allergic diseases,and IgE is indispensable factor in development of asthma.IgE-antigen crosslinking of hish affinity IgE receptor(FcεRⅠ)leads to degranulation of mast cell,leukotriene synthesis and cytokine production.As a re8ult.such changes will bring about inflammation of airway and spasm of airway smooth muscle.Recent researches suggest that Src tyresine kinase play a vital role in their combination.This review discusses the regulation and signaling trannduction of FcεR Ⅰ and the relationship between FcεRⅠ and asthma.