Carotid artery stenting is one of the main methods for the treatment of carotid artery stenosis.However,as a severe complication after stenting,restenosis has restricted its clinical application to a certain extent.At present,the pathogenesis of restenosis after stenting is not very clear.More and more studies have shown that it may be associated with vascular endothelial injury,platelet aggregation,and inflammatory response.This article reviews the pathophysiological mechanisms of restenosis alter stenting.

[Purpose] To observe the clinical effects, relapse rate and security of treating the verruca plana with the cure warts capsules combined with Burt's res-q ointment. [Methods] Eighty patients with verruca plana were randomly divided into two groups. Forty patients in the combination group received cure warts capsules combined with Burt's res-q ointment; others in the control group received 0.1% al-transretinoic acid cream only. The courses of treatment of two groups was four weeks, then observe the number of verruca plana and bad reaction after the treatment, and record four weeks fol ow-up observation of relapse. [Results] The effective rate of treatment group was 92.50%which was significantly higher than the control group that the effective rate was 50.00% , and the former’s relapse rate was 3.40% which was significantly lower than that in the group which was 44.40% , the above showed significant difference(P<0.05).There was no significant side effects in the two groups. [Conclusion] Cure warts capsules combined with Burt's res-q ointment had better effect, low relapse rate and high safety.

Dentists

Objective: To observe the pathophysiological changes of dogs with open abdominal injury and seawater immersion-induced acute heart failure. Methods: Adult mongrel dogs were randomly divided into open abdominal injury+ seawater immersion group (group A, n=8) and simple open abdominal injury group (group B, n=8). The cardiac rhythm, heart rate, systolic pressure, diastolic pressure, mean arterial pressure, pulmonary wedge pressure, central venous pressure, cardiac output, heart index, rennin, B-type brain natriuretic peptide (BNP), other relevant parameters and death rate were observed before and after open abdominal injury, during 2h seawater immersion, and at different time points after getting out of the water. The left ventiricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), stroke volumes (SV), and left ventricular ejection fraction (LVEF) were measured before and 4 h after injury by ultrasonic cardiogram. Results: The mean arterial pressure decreased significantly in group A from 5 min after injury to the end of the ovservation (P<0.05, P<0.01), and that of group B had no measurable changes. The pulmonary capillary wedge pressure (PAWP) increased significantly; the central venous pressure, cardiac output, and cardiac index decreased gradually, and continued to decrease after putting out of water,which were significantly different from those of group B(P<0.05, P<0.01). Group B had no measurable changes in PAWP, central venous pressure, cardiac output, and cardiac index before and after abdominal injury. The blood rennin and BNP levels were significantly increased in group A (P<0.05, P<0.01) and had no significant changes in group B. Conclusion: Prominent pathophysiological changes occur in rats with open abdominal injury and seawater immersion-induced acute heart failure.

In the complications of dental implant treatment, the mechanical complications, such as central screw breakage, are often complex and serious. This article analyzes factors that affect the loosening of the central screw. Understanding relevant risk factors can prompt doctors to take corresponding strategies to reduce the possibility of complications in clinical operations. After encountering broken cases, this paper also gives some ideas and methods of treatment, and finally summarizes clinical suggestions for preventing the central screw fracture.

ObjectiveTo observe the effect of Muscle Stimulating Instrument in enforcing the strength of weaken muscles after selective posterior rhizotomy (SPR). MethodsA group of 27 patients with spastic cerebral palsy aging from 3 to 10 years at the average of 5.7 years were treated with the instrument after SPR. A control group of 36 cases was adopted. Muscle strength, gait and motor function amelioration were compared between two groups. ResultsResults of treatment group in both muscle strength and motor function are better than those of the control group (P<0.05).ConclusionsMuscle stimulating instrument is effective to tone up the muscles which patients felt weak after SPR, and to accelerate the course of rehabilitation.

Laser peripheral iridotomy ( LPI) is one of the main therapy for glaucoma due to its reliable efficacy of widening peripheral angle and therefore decreasing intraocular pressure by partially relieving pupillary block. The parameters of the anterior chamber angle following the LPI are the main evaluation indexes. At present,the detecting and diagnosis technique for the anterior chamber angle is deeply advancing, including gonioscopy, ultrasound biomicroscopy, anterior segment optical coherence tomography and Pentacam. These methods offer some useful parameters and also present with some limits in the application respectively in the evaluation of anterior chamber and angle structure. This review focuses on the application of Methods mentioned above and morphologic changes of anterior chamber and angle structure following the LPI.

Adipocytes ; chemistry ; Blood Vessels ; Cytokines

Hepatitis C virus(HCV)is the major etiology of non-A,non-B hepatitis.At present,neither a vaccine nor any effective therapy is available.Multi-epitope DNA vaccine(minigenes/epigenes)is a novel nucleic acid vaccine which can induces high effective cellular and humoral immune responses and has good perspective in clearing Hepatitis C virus through screening and assembling optimal antigen epitope genes(T cell、B cell epitope included).It is advanced in covering more HCV subtypes,inducing comprehensive anti-HCV immune responses and reducing the negative influence caused by irrelevant,disturbing and suppressive sequence as far as possible through selecting the most potential protective epitopes in DNA vaccine design.The recent research progress on HCV compound multi-epitope DNA vaccine and future prospects were reviewed.

The potential impacts of future climate changes on human health are having been widely paid more attention to.The direct and indirect potential impacts of future possible changes of climate on human health were reviewed in this paper.The methods for assessing the impacts of climate changes on human health were introduced also