1.Accelerating the professional clinical research team building in the process of transforming towards research-oriented hospitals
Lijun ZHU ; Shani CHENG ; Hao WANG ; Yeye DU ; Wanrong PAN ; Xiaojing XU ; Huijun LIU ; Shansheng ZHOU ; Haiying ZHU ; Shan MOU ; Jianzheng ZHU
Journal of Shanghai Jiaotong University(Medical Science) 2017;37(6):715-718
Building a professional clinical research team inside hospitals is in favor improving their research abilities,accelerating the clinical discipline construction,improving their comprehensive influence.Also it fits the objective of general hospital development under gate-keeping system.Now in domestic,the percentage of professional research staff in large hospitals accounts was much less than the international level.The main reasons included the misunderstanding of constructing the research-oriented hospitals,insufficient human resources enrollment,less attractive environment to the highlevel researchers and the absence of relevant degree training programs.To enhance the construction of research-oriented hospitals,it's of key importance to build the professional research team in hospitals.Besides,the hospital has to update management conception,broaden the channels of talent cultivation,grasp the development of the subject accurately and interact with the basic medicine and public health subject,increase the financial investment and perfect the relevant management regulations.
2.Research on the technological process and methods of the comprehensive pharma-ceutical experiment of rutin tablets
Li CHEN ; Hongli DU ; Rentao ZENG ; Yeye ZHANG ; Ying LU ; Guojun CAI
Journal of Pharmaceutical Practice 2015;(4):359-362
Objective To imitate the development process of new drugs with rutin as the model and to do multidiscipli-nary experiments of preparation and pharmacodynamics of rutin tablets .Methods Thin-layer chromatography was used to i-dentify rutin in Pagodatree flower bud .High-performance liquid chromatography was used for quantitative determination of ru-tin in Pagodatree flower bud and rutin products .The vasodilatation effect of rutin was investigated .The preparation of rutin tablets was completed .Results and Conclusion We completed the identification of Pagodatree flower bud ,extraction and puri-fication of rutin from Pagodatree flower bud ,the assay of rutin ,the pharmaco-dynamics study and the formulation of rutin tab-lets .The experiments helped the postgraduates to be familiar with the research process of new drugs and to improve their ex-perimental operation skills .