1.Efficacy of radiotherapy on nasal natural killer/T-cell lymphoma and prognostic analysis
Tao REN ; Bangxian TAN ; Mi LIU ; Daiyuan MA ; Yeqin ZHOU ; Xiaohong SHU ; Ji ZHOU
Journal of Leukemia & Lymphoma 2011;20(3):165-167,171
Objective To retrospectively analyze the efficacy of radiotherapy on nasal NK/T-cell lymphoma, and to explore the prognostic factors. Methods Between January 2000 and December 2008, 62 patients with nasal NK/T-cell lymphoma were treated with radiotherapy in our hospital. Their clinic data and efficiency were reviewed retrospectively. Kaplan-Meier methods were applied in unifactorial analysis and the COX regression model was applied in multivariate analysis. Results The median overall survival time was 69.7 months (95 % CI, 63.0-78.0 months), and 3, 5-year survival rate was 66.1% and 46.8 %. Metastasis was 61.8 % for the first reason which resulted in failure. The median survival time was 72.6 months in the increased group of numbers of T lymphocyte CD3 and 39.6 months in the decreased group, the difference was significant(x2 =4.9309, P =0.0264). Multivariate analysis confirmed that modified IPI 0-1 (x2 = 7.5266, P =0.0061), the numbers increased for CD3 (x2 =9.0912, P =0.0266), and complete remission(x2 = 9.0912, P =0.0106) were significant favorable prognostic factors for survival. Conclusion The radiotherapy was effective for patients with nasal NK/T-cell lymphoma, but was failure on account of distant metastasis, so systematic therapy still has an important role. modified IP1 0-1, the number increased for CD3 and complete remission were significant favorable prognostic factors for survival.
2.Impact of CT scanning condition on the precision and accuracy of target position
Xianfu LI ; Bangxian TAN ; Mi LIU ; Yujun LUO ; Yeqin ZHOU ; Jin HU ; Daiyuan MA
Chinese Journal of Radiation Oncology 2009;18(2):142-145
Objective To study the effect of CT scanning condition on the target position coordinate with WIMRT radiotherapy planning system using the" Z" form localizing frame. Methods The whole Head Phantom containing three metal targets was scanned under the following conditions: localizing frame transver-sally tilting, CT gantry tilting and localizing frame axially tilting. Then the three target coordinates were com-puted respectively and compared with those under the standard condition. Results The height and width of coordinate under the localizing frame transversally tilting condition deviated from those under the standard scanning condition,which was in an angle dependent manner. On the other hand ,a tendency was shown that the greater the absolute height value of the targets coordinate, the greater the width value deviation. And so was the relation between the absolute width value of the coordinate and height value deviation. If CT gantry angle was not zero degree or localizing frame axis is not in the same line with the CT bed moving direction, the calculated longititude value of the targets coordinate was mainly affected. Conclusions CT scanning must be performed strictly under the standard localizing scanning condition by a proficient physicist.
3. Construction and application of pharmaceutical service model of traditional Chinese medicine combined outpatient in the first affiliated hospital of Suzhou university
Lin CHEN ; Yeqin MAO ; Xiang ZHOU ; Zongqi CHENG
International Journal of Traditional Chinese Medicine 2019;41(11):1161-1164
This paper introduces the construction and application of "TCM combined outpatient" in the first affiliated hospital of suzhou university. The joint outpatient is set up with senior specialists and clinical pharmacists, and independently developed the traditional Chinese medicine prescription audit system and the pharmaceutical service intelligent platform based on mobile internet technology. The multi-channel doctor- patient-pharmacist exchange platform is set up to assist doctors in drugs selection and patients management with certain achievements.
4.Influence of the surgery concept of rapid rehabilitation on the postoperative rehabilitation, immune function and nutritional status of patients with colorectal cancer undergoing laparoscopic radical surgery
Wengang QIU ; Hongliang CHEN ; Jun LIANG ; Jun XIE ; Yeqin ZHOU
Chinese Journal of Primary Medicine and Pharmacy 2020;27(10):1212-1216
Objective:To explore the effect of the surgery concept of rapid rehabilitation on the postoperative rehabilitation, immune function and nutritional status of patients with colorectal cancer undergoing laparoscopic radical surgery.Methods:From June 2017 to June 2019, 106 patients with colorectal cancer underwent laparoscopic radical surgery in the Affiliated Hospital of Shaoxing University of Arts and Sciences were divided into the observation group and the control group according to the random digital table method, with 53 cases in each group.The observation group adopted the surgery concept of rapid rehabilitation, while the control group adopted the surgery concept of conventional rehabilitation.The amount of intraoperative bleeding, postoperative complications and operation time were compared between the two groups.The recovery of gastrointestinal function, the changes of immune function and nutritional indicators were compared between the two groups.Results:There were no statistically significant differences in the amount of bleeding and operation time between the two groups(all P>0.05). The incidence of postoperative complications in the observation group was 5.66%(3/53), which was lower than 24.53%(13/53) in the control group(χ 2=7.361, P<0.05). The time of first anal exhaust[(2.14±0.32)d] and first eating[(1.85±0.42)d]in the observation group were shorter than those in the control group[(3.62±0.61)d and (2.79±0.36)d]( t=15.642, 12.371, all P<0.05). Three days after operation, the CD 3+ [(50.82±2.31)%], CD 4+ [(34.01±2.19)%]and CD 4+/CD 8+ (1.03±0.08) in the observation group were higher than those in the control group[(46.30±2.68)%, (30.26±2.05)% and (0.81±0.12)]( t=9.300, 9.101, 11.105, all P<0.05). The serum transferrin[(1.97±0.14)g/L]and prealbumin[(0.23±0.03)g/L] in the observation group were higher than those in the control group[(1.72±0.15)g/L and (0.18±0.03)g/L]( t=8.870, 8.580, all P<0.05). Conclusion:The surgery concept of rapid rehabilitation can promote the postoperative rehabilitation of patients with colorectal cancer, improve the immune function and nutritional status of patients, and has less complications.
5.Analysis on property of meridian supramolecules by biological evolution path.
Kaiwen DENG ; Yeqin TAO ; Wenhan TANG ; Fuyuan HE ; Wenlong LIU ; Jilian SHI ; Yantao YANG ; Yiqun ZHOU ; Xiaorong CHANG
Chinese Acupuncture & Moxibustion 2017;37(3):325-330
With human placed in the whole nature, by following the biologic evolution path, the property of channel structure for "imprinting template" in meridian andwas explored with supramolecular chemistry. In the history of biologic evolution, each molecule in "molecule society" gradually developed into various highly-ordered supramolecular bodies based on self-identification, self-assembly, self-organization, self-replicating of"imprinting template", and thereby the original biochemical system was established, and finally evolved into human. In the forming process of supramolecular bodies, the channel structure of"imprinting template" in guest supramolecular bodies would be kept by host supramolecular bodies, and communicate with the outside to exchange materials, energy, information, otherwise life phenomenon could not continue, for which it was the chemical nature of biolo-gical supramolecular bodies for body to develop meridian. Therefore, the human was a gigantic and complicated supramolecules body in biological nature, and possessed the supramolecules "imprinting template" at each stage of evolution, for which the meridians were formed. When meridians converged, acupoints appeared; when acupointsconverged,appeared. With the promotion of the blood from heart, according to"imprinting template", the guest supramolecular bodies and host meridian produced-analysis, which was the-phenomenon of guest in meridian. It presented asimage of physiology and pathology as well as action regularities of medication and acupuncture tolerance, by which current various meridian viewpoints could be explained and propose the hypothesis of meridian supramolecular bodies. The meridian and its phenomenon was decide by its "imprinting template" of supramolecular bodies and self-reaction regularities, which abided through the living nature. This was the substance for meridian biology.