1.Application of Key Performance Indicators Project Management in TCM Pharmacy of General Hospital
China Pharmacy 2005;0(23):-
OBJECTIVE: To investigate the application of key performance indicators (KPI) project management in TCM pharmacy of generl hospital.METHODS: KPI project management system which is established by TCM pharmacy and the specific process of implementation were analyzed and summarized.RESULTS: KPI project management improved performance management of TCM pharmacy and confirmed target of position.CONCLUSION: Comprehensive KPI management model should be set up in TCM pharmacy and play great role in general hospital.
2.Analysis of quality of life and depression in patients with androgenetic alopecia or alopecia areata
Yu MAO ; Yeqin DAI ; Chunqiu SUN ; Aie XU
Chinese Journal of Dermatology 2017;50(5):360-363
Objective To assess the quality of life, prevalence of depression and their influencing factors in patients with alopecia, to investigate, and to provide evidences for relevant clinical therapeutic strategies to improve patients′ quality of life. Methods A questionnaire survey was carried out in 237 patients with androgenetic alopecia or alopecia areata, and their quality of life and depression were measured using dermatology life quality index(DLQI)and center for epidemiologic studies depression scale (CES-D), respectively. Factors influencing the quality of life and depression were analyzed by analysis of variance and logistic regression analysis. Results Among 237 patients with alopecia, 218 questionnaires were eligible with the mean score of DLQI being 9.1 ± 5.4. Alopecia had a moderate effect on the quality of life in general, and 38.07%of the patients were severely affected. The mean score of CES-D was 14.8 ± 9.9, and 37.61%of the patients showed depressive tendency. The DLQI score was positively correlated with CES-D score(r=0.29, P<0.01). One-way analysis of variance(ANOVA)showed that the DLQI score was not affected by age, gender, education level or the number of visits. Multivariate logistic regression analysis revealed that the risk factors for depressive tendency in patients with alopecia were the number of visits (OR = 1.81, 95% CI: 1.21- 2.69) and DLQI score (OR = 1.08, 95% CI: 1.03- 1.13). Conclusion Alopecia not only affects the quality of life, but also mental states of patients.
3.Clinical Observation of Xiaozhen Zhiyang Spray in the Treatment of EGFRI-associated Rash
Lin CHEN ; Zongqi CHENG ; Min TAO ; Yeqin MAO ; Zhaowei YAN ; Weihua SONG
China Pharmacy 2017;28(17):2370-2373
OBJECTIVE:To observe the clinical efficacy and safety of Xiaozhen zhiyang spray in the treatment of EGFRI-asso-ciated rash. METHODS:A total of 60 malignant tumor patients suffering from rash induced by EGFRI were divided into trial group (40 cases)and control group(20 cases)according to the patient's willingness. Control group didn't received any therapy for rash. Trial group received Xiaozhen zhiyang spray for several times a day according to the degree of rash as 1-2 times/d for first degree, 2-3 times/d for second degree,3-5 times/d for third degree,and the treatment course lasted for 2 weeks. Rash degree and improve-ment,itching degree and improvement,daily life quality index(DLQI)score before and after treatment as well as the occurrence of ADR were compared between 2 groups. RESULTS:before treatment,there was no statistical significance in rash and itching de-gree,or DLQI score between 2 groups(P>0.05). After treatment,rash and itching degree of trial group were improved significant-ly compared to before treatment and control group,with statistical significance(P<0.05). The total response rates of rash and itch-ing therapy in trial group were significantly higher than control group(67.50% vs. 20.00%,70.00% vs. 15.00%),with statistical significance(P<0.05). DLQI score of trial group was significantly lower than before treatment and control group,with statistical significance(P<0.05). There was no statistical significance in DLQI score of control group before and after treatment(P>0.05). No obvious ADR was found in trial group. CONCLUSIONS:Xiaozhen zhiyang spray can effectively relieve EGFRI-associated rash and itching as well as improve the quality of life for patients.
4. Construction and application of pharmaceutical service model of traditional Chinese medicine combined outpatient in the first affiliated hospital of Suzhou university
Lin CHEN ; Yeqin MAO ; Xiang ZHOU ; Zongqi CHENG
International Journal of Traditional Chinese Medicine 2019;41(11):1161-1164
This paper introduces the construction and application of "TCM combined outpatient" in the first affiliated hospital of suzhou university. The joint outpatient is set up with senior specialists and clinical pharmacists, and independently developed the traditional Chinese medicine prescription audit system and the pharmaceutical service intelligent platform based on mobile internet technology. The multi-channel doctor- patient-pharmacist exchange platform is set up to assist doctors in drugs selection and patients management with certain achievements.
5.Research on the management standard of medical safety (adverse) events
Yuan YAO ; Yeqin SUN ; Li MAO ; Yongbin LI ; Wei LI ; Wenxin WANG ; Lihua LIU
Chinese Journal of Hospital Administration 2018;34(12):984-988
The authors developed a standard of medical safety ( adverse) events standardization management, according to the principle of medical safety (adverse) event management, domestic and abroad research results and best practices for medical safety ( adverse) events management, as well as the present specifics and practice of hospital management in China. Such a standards is designed to standardize such key points of medical safety ( adverse) event management in China, namely the definition, classification, risk prevention, reports response and continuous improvement, which serves as an icebreaker for scientific management of medical safety (adverse) events.
6.Study on clinical efficacy and safety of Fuzheng yangxue ointment on myelosuppression induced by chemotherapy
Lin CHEN ; Zongqi CHENG ; Xin YAO ; Yeqin MAO
China Pharmacy 2022;33(21):2643-2646
OBJECTIVE To observe the clinical efficacy and safety of Fuzheng yangxue ointment in the intervention of chemotherapy-induced myelosuppression . METHODS The data of 200 patients were collected retrospectively ,who were diagnosed as malignant tumors in our hospital for the first time from January 2018 to December 2020 and were to receive the chemotherapy scheme of “paclitaxel combined with platinum ”. According to whether Fuzheng yangxue ointment was used or not ,they were divided into trial group and control group ,with 100 cases in each group . The control group received routine chemotherapy ,and the trial group took Fuzheng yangxue ointment orally after the first chemotherapy until the end of this chemotherapy cycle . The time of the first occurrence of myelosuppression ,the incidence of myelosuppression ,the use of rescue drugs ,quality of life and other indicators were compared between 2 groups. RESULTS After the first chemotherapy ,white blood cell count ,neutrophil count ,the levels of platelet and hemoglobin in control group were significantly lower than those before the first chemotherapy (P<0.05). The white blood cell count and neutrophil count of patients in the trial group were significantly lower than those before the first chemotherapy(P<0.05),but significantly higher than those in the control group (P<0.05). The incidence of myelosuppression in the trial group (39.00%) was significantly lower than that (63.00%) in control group (P<0.05). The occurrence time of myelosuppression for the first time in the trial group (11.0th day after chemotherapy )was later than that in the control group (6.7th day after chemotherapy ). During the first chemotherapy cycle ,the number of patients in the control group (28 cases)using drugs for increasing white cells was significantly higher than that in the trial group (11 cases)(P<0.05). After the first chemotherapy , KPS scores of patients in both groups were significantly lower than those before the first chemotherapy (P<0.05),but KPS scores of patients in the trial group were significantly higher than those in the control group (P<0.05). After the first chemotherapy, the scores of fatigue , anorexia, dizziness,palpitation,nausea and vomiting ,and spontaneous sweating and night sweating in 2 groups were significantly higher than those before the first chemotherapy ,but the scores of spontaneous sweating and night sweating in the trial group were significantly lower than those in the control group (P<0.05). The levels of glutamic pyruvic transaminase ,glutamic oxaloacetic transaminase ,urea and creatinine in the two groups were within the normal range before and after the first chemotherapy . CONCLUSIONS Fuzheng yangxue ointment can effectively reduce the incidence of chemotherapy-induced myelosuppression ,delay the time of myelosuppression ,reduce the consumption sum of clinical remedial drug for increasing white cells/ for increasing platelet ,reduce the score of TCM syndrome and improve the quality of life of patients.