5.Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children.
Chinese Journal of Contemporary Pediatrics 2008;10(1):102-104
Anti-Bacterial Agents
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pharmacology
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Child
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Dyspepsia
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drug therapy
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Erythromycin
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analogs & derivatives
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pharmacology
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therapeutic use
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Gastroesophageal Reflux
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drug therapy
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Gastrointestinal Motility
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drug effects
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Humans
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Motilin
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pharmacology
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Receptors, Gastrointestinal Hormone
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drug effects
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Receptors, Neuropeptide
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drug effects
8.Treatment of Angina Coronary Artery Disease of 30 Cases with Self-made Huoxue Kuanxiong Decoction
International Journal of Traditional Chinese Medicine 2008;30(2):133-134
Objective To observe the effect of Huoxue Kuanxiong decoction on symptoms and Electrocardiogram changes of angina coronary artery disease.Methods 60 patients were randomly divided into treatment group and control group.Patients in the treatment group were treated by Huoxue Kuanxiong decoction,with one preparation daily for twice uses.Patients in the control group were treated by Isosorbide Mononitrate,20mg,12Qh.The therapeutic course for both groups was four weeks.Results In the treatment group,the distinct effective rate and the total effective rate were 20.0%and 86.7%respectively for angina coronary artery disease,and 16.7% and 76.7% respectively for electrocardiogram.In the control group,The distinct effective rate and the total effective rate were 16.7% and 53.3% respectively for angina coronary artery disease.and 13.3% and 46.7% respectively for electrocardiogram.Conclusion Huoxue Kuanxiong decoction is effective to the patients of angina coronary arterary disease.
9.Dynamic distribution of foot pressure when undergraduates jog
Chinese Journal of Tissue Engineering Research 2009;13(46):9109-9112
BAcKGROUND:The specific research on the interaction between feet and ground when jogging,plays an important role for a deeper understanding of the basic laws of human motion.OBJECTIVE:To test dynamic foot pressure distribution during jogging of 64 undergraduates.DESIGN,TIME AND SETTING:A single sample design,the experiment was carried out in Tianjin Normal University Sports Institute in March 2009.PARTICIPANTS:A total of 68 male collego students,without history of foot traumatic or deformities and with normal ankle joint,were involved in this study.METHODS:Totally 68 university students were analyzed by the Footacan USB2 system(RSscan,Belgium)when jogging atnormal gait(5m/s).Dynamic foot pressure was determined three times.Analysis of foot pressure distribution system could gain a complete gait cycle of foot pressure distribution,data acquisition and analysis software used footscan SOFTWARE7.0,foot process of analysis was divided into 10 regions:the first phalange,the second to the fifth phalanges,the first metatarsal,the second metatarsal,the third metatarsal,the fourth metatarsal,the fifth metatarsal,arch,medial heel and lateral heel.MAIN OUTCOME MEASURES:Foot pressure,intensity of pressure,force interval and impulse when jogging.RESULTS:The foot stress-time curve showed a single peak;foot maximum pressure located at the second metatarsal,the site of impulse descending order was the third metatarsal.the first metatarsal,heel,the first phalange,the fourth metatarsal,the fifth metatarsal,the second to the fifth phalange,arch;the distribution of both feet was similar.The pressure of right foot in the second metatarsal,the first metatarsal and the first phalange was significantly greater than the left foot;The contact phases of the full foot and deport from ground occupied 90% of support time,the pressure center was densely in the middle of half sole,the fore intarval of sole was long.The contact time of right foot was significantly larger than left foot.The biggest impulse was the site of the second metatarsal,the order from great to small was the first metatarsal,the third metatarsal,the first phalange,heel,the fourth metatarsal,arch.the second to the fifth phalange,the fifth metatarsal;the distribution of both feet was similar.The impulse of right foot was greater than left foot,while the impulse of the second metatarsal,the first metatarsal and the first phalange were greater than left foot,the difference had statistical significance.CONCLUSI0N:The largest pressure part is the second metatarsal when jogging,the pressure center in the foot locates in the middle of half sole,and the largest impulse is the second metatarsal,most of the impulse focus on the front end of the first to the third metatarsals of the half sole.It is indicated that the middle part of the footpad would be injured easily when jogging,so we should pay attention to the selection of shoes when exercising.
10.Molecular diagnosis in personalized therapy for cancer
Cancer Research and Clinic 2010;22(11):721-723
In recent years, the study on the molecular mechanism of tumorigenesis and cancer cell signals promotes the application of cancer-targeted therapy, which aims at cell receptors, key genes, and regulatory molecules in cancer cells. However, the polymorphism of targeting genes/molecules determines the clinical efficiency of these therapies. The application of gene polymorphism diagnosis in cancer-targeted therapy was reviewed.