2.Efficacy assessment of treating post-stroke shoulder-hand syndrome patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome by yishen tongluo decoction.
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(9):1069-1073
OBJECTIVETo assess the efficacy of Yishen Jiejing Decoction (YJD) in treating poststroke shoulder-hand syndrome (SHS) patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome.
METHODSTotally 60 SHS patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome were randomly assigned to two groups, the treatment group and the control group, 30 cases in each group. Conventional rehabilitation training and therapeutics were applied in all patients. Besides, patients in the treatment group took 50 mL YJD, twice a day. One month without interruption consisted of one course of treatment. The curative effects of each group were evaluated respectively before treatment and at one month after treatment. The neurologic impairment, TCM syndrome, and the improvement of upper limbs movement were assessed by the neurologic impairment integral, scoring for TCM syndrome diagnostics, Fugl-Meyer Assessment (U-FMA). Adverse reactions were observed at the same time.
RESULTSThe effective rate of stroke was 86.67% and the effective rate of SHS was 90.00% in the treatment group, higher than those of the control group (P < 0.05). Both groups got improvement in neurologic impairment, stroke induced blood stasis syndrome, yin deficiency yang hyperactivity syndrome, and the improvement of upper limbs movement after treatment (all P < 0.05). Besides, all the improvement was obviously superior in the treatment group (P < 0. 05). No adverse reaction occurred during the course of treatment.
CONCLUSIONThe curative effect of YJD combined with conventional rehabilitation training was confirmative and superior to the control group.
Aged ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Reflex Sympathetic Dystrophy ; drug therapy ; etiology ; rehabilitation ; Stroke ; complications ; Treatment Outcome ; Yin Deficiency ; drug therapy ; Yin-Yang
3.Prevalence of benign prostatic hyperplasia in Beijing: a multicentre community-based cross-sectional survey
Ye TIAN ; Qiang SHAO ; Jian SONG
Chinese Journal of Urology 2010;31(3):194-198
Objective To investigate the prevalence of benign prostatic hyperplasia (BPH) in Beijing. Methods A cross-sectional study was performed at Beijing communities in men aged over 50 years. The International Prostate Symptom Score (IPSS) questionnaire was used to evaluate the symptoms. Transabdominal ultrasonography was used to measure prostate size and the residual urine volume(RUV). Uroflowmetry was performed to record the maximum flow(Q_(max)). One-way ANOVA was used to analysis the differences. Results 1644 subjects were enrolled and the mean age was 64. 5 years (range 50 - 93 years). The mean IPSS, prostate weight andQ_(max) were 9. 9±8. 2, (30. 8± 19.4) and (14. 7 ± 7. 5)ml/s, respectively. They had correlation with age (r=0. 388,0. 262, - 0.371). The prevalence of moderate-severe lower urinary tract symptoms (LUTS) was 50. 8% (835/1644). Prostate volume was greater than 20 ml in 69. 7%(1146/1644) of the subjects.Q_(max) was less than 15 ml/s in 53. 8% (883/1642) of the subjects. Conclusions In men age over 50 years in Beijing, there is positive correlation between LUTS, prostate size and age, and negative correlation between Q_(max) and age. The prevalence of BPH, defined as IPSS greater than 7, maxium flow rate less than 15 ml/s and prostate size greater than 20 ml, is 26. 8%(441/1644).
4.Clinical Characteristic of Hospital Infections in Patients of Urological Surgery
Guomin ZHANG ; Weifeng YE ; Xiaobin SHAO
Chinese Journal of Nosocomiology 2009;0(22):-
OBJECTIVE To discuss the clinical characteristics of hospital infection and countermeasures urological surgery patients.METHODS The retrospective survey methods,statistical urology hospital infection rates,infection site,pathogen test results,the impact of infection on the prognosis and the risk factors for infection were analyzed.RESULTS The incidence of hospital infection was 9.30% and the infection sites were urinary tract(43),lower respiratory tract(16),upper respiratory tract(4),wound infection(10),gastrointestinal tract(antibiotic-associated diarrhea)(6) and oral cavity(1).The main pathogens(detection rate 76.05%) were Escherichia coli 20 cases,Klebsiella pneumoniae(8),coagulase-negative staphylococci in(6),Pseudomonas aeruginosa(5),Enterococcus(4),Proteus vulgaris(3),Staphylococcus aureus(2) and Candida albicans(6).The Older,the combined underlying diseases,the implementation of indwelling catheter,especially with a long time and long operation time,and hospital infections were the risk factors.Preventive use of antibiotics could not reduce hospital infections;The dead rate(3.75%) in infection group was higher than that in non-infected group(0.38%,P
5.Distribution and Antimicrobial Resistance of Acinetobacter baumannii Infection in Elderly Patients
Jianxiong LU ; Yirui LI ; Ye SHAO
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To investigate the distribution and antimicrobial resistance of Acinetobacter baumannii infection in the elderly patients in our hospital. METHODS One hundred and eighty-four strains of A. baumannii isolated from elderly patients with infection from Jun 2001 to Apr 2005 were collected and antimicrobial susceptibility test was performed. RESULTS All strains of A. baumannii were from sputum, urine, pus, etc; the resistance of the strains to the third generation cephalosporin, ciprofloxacin and ofloxacin was all more than 50.0% ; the resistance rate to imipenem was the lowest(2.2%), followed by amikacin (37.5%)and ampicillin/ sulbactam (39.7%), and the resistant rate to ampicillin was the highest( 83.2% ). CONCLUSIONS The antimicrobial resistance of A. baumannii in the elderly patients is high, the antibiotic treatment must depend on antimicrobial susceptibility test.
6.Application progress of doppler optical coherence tomography in eye diseases
Linhong YE ; Jing BAO ; Yi SHAO
Recent Advances in Ophthalmology 2017;37(7):680-683
Optical coherence tomography (OCT) has played a revolutionary role in the development of ophthalmology.Since the 1990s,it has been constantly improved in terms of speed,resolution and sensitivity.The technique has also seen a variety of extensions aiming to assess ftmctional aspects of the tissue.Doppler combined with OCT technology (DOCT) can provide 3D vascular images,also referred to as the OCT angiography.DOCT can achieve visualization,quantitative blood flow,scanning of layer retinal blood vessels,and the scanning speed is fast.It has depth resolution,clear image.As a new noninvasive optical imaging technique,DOCT can realize retinal vascular network images and provide meaningful image data.It is a major breakthrough on the eye detection methods and helpful in diagnosis,monitoring for the eye disease in the future.This article reviews the application progress of DOCT in eye diseases.
7.Hypertension and recurrence of stroke:a case-control study
Hui YE ; Jiaomei SHAO ; Jiangang JIANG
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Objective To evaluate the relationship between hypertension and recurrence of stroke,and to search for the risk factors.Methods The study was done from Dec.2000 to Jun.2002 at Tongji Hospital.The study consisted of 300 hospitalised patients,of which computerized tomography scan proved 100 cases of haemorrhagic stroke and 200 cases of ischemic stroke,and an age and sex matched control per case.The controls were selected from healthy people.We observed difference between stroke and control people in the results of one-year follow-up.Results The recurrence rate of stroke was 10.34% in stroke patients,which was significantly higher than the rate in controls(0.34%)(P
8.Preparation and Quality Control of Boric Acid Wet Compress Towelettes
Dan SHAO ; Yingen LIAO ; Fashun YE
China Pharmacy 1991;0(03):-
OBJECTIVE:To prepare boric acid wet compress towelettes and to establish a method for its quality control.METHODS:Wet compress towelettes containing3%of boric acid solution was prepared with absorbent gauze(six layers in thickness)of different specifications as carrier,assaying of boric acid solution adsorbed into the carrier was performed by volumetric analysis.RESULTS:The preparation is smooth in appearance,airtight sealed and its content of boric acid solution was up to standard.CONCLUSION:The preparation is simple in preparative method,stable and controllable in quality.
9.Clinical efficacy of irbesartan hydrochlorothiazide combine with bisoprolol fumarate on juvenile hypertension
Qizeng WANG ; Jianzhi SHAO ; Chenxi YE
Chongqing Medicine 2015;(35):4962-4964
Objective To observe and explore the effectiveness of irbesartan hydrochlorothiazide(IH) combine with Bisoprol‐ol fumarate(BIS) on youth hypertension .Methods Randomly divided 96 patients in our hospital from September 2012 to February 2015 into observation group and control group(48 cases in each/group) .the IH treatment was given to the control group based on regular drug ,while the BIS was given to the observation group on the basis of the control group .systolic pressure(SBP) ,diastic pressure(DBP) and heart rate(HR) ,left ventricular end diastolic diameter(LVEDD) ,E peak and left ventricular ejection fraction (LVEF) in the two groups before and after treatment were detected ,and comprehensive efficacy were evaluated based on blood pressure improvement .Results Before treatment ,the difference of SBP ,DBP ,HR ,LVEDD ,E peak and LVEF between the two groups was not statistically significant (P>0 .05);after treatment ,SBP ,DBP and HR were (116 .4 ± 11 .8)mm Hg ,(85 .3 ± 6 .7) mm Hg and (65 .2 ± 7 .1)times/min in the observation group ,respectively ,while in the control group ,SBP ,DBP and HR were (132 .8 ± 14 .6)mm Hg ,(96 .3 ± 6 .2)mm Hg and (75 .2 ± 8 .1)times/min ,respectively ,the difference was statistically significant(P<0 .05);after treatment ,LVEDD in observation group was significantly lower than the control group ,while LVEF ,E peak were significantly higher(P< 0 .05);the total effective rate in observation group was 95 .8% (46/48) ,while total effective rate was 75 .0% (36/48) in the control group ,the difference was statistically significant(P<0 .05) .Conclusion IH combined with BIS can significantly improve blood pressure in patients with juvenile hypertension and has significant effect ,thus it is a safe and effective therapy for juvenile hypertension .
10. Effects of non-dependent antiepileptic agents on addiction disease
Chinese Pharmacological Bulletin 2002;18(2):129-131
Addiction diseases make patients dependent on drug abused or some kind of behavior, and seriously impair their physical and mental health. Drug therapy for this kind of disease has got increased attention in recent years besides non-drug treatment measures. Dependentless antileptic agents such as carbamazepine and phenytoin show their effective effects on some symptoms like withdrawal syndrome and craving. The mechanisms of addiction diseases and the drug's effects was discussed. Comparative study was made addiction disease and epilepsy.