4.Intensity-modulated radiotherapy for early-stage breast cancer after breast-conserving surgery
Journal of International Oncology 2010;37(1):53-56
Conventional radiotherapy after breast-conserving surgery is generally delivered to the overall breast over a period of 5 to 6 weeks,but its negative effects are significant.With the development of radiotherapy techniques,achieving optimal curative effect with least invasion becomes the researchers aims.Intensitymodulated radiotherapy(IMRT) has come to the forefront as a potential alternative.IMRT attracts more and more attention ,and has a promising perspect.IMRT may become the standard treatment for early-stage breast cancer after breast conservation treatment.
5.Observation on the Efficacy of Acupuncture plus Cognitive Function Training in Treating Parkinson's Disease Dementia
Shanghai Journal of Acupuncture and Moxibustion 2016;35(9):1053-1055
Objective To observe the clinical efficacy of acupuncture plus cognitive function training in treating Parkinson's disease dementia.Methods Sixty Parkinson's disease dementia patients were randomly allocated to a treatment group and a control group, 30 cases each. The treatment group was intervened by acupuncture plus cognitive function training, and the control group by conventional drug treatment. The Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) were recorded in the two groups before and after the treatment. The therapeutic effects were compared between the two groups.Results The MMSE score and MoCA score were significantly changed after treatment in the two groups (P<0.05). There were significant post-treatment differences in the MMSE score and MoCA score between the treatment group and control group (P<0.05). The total effective rate was 90.0% in the treatment group versus 70.0% in the control group, and the difference was statistically significant between the two groups (P<0.05).Conclusions Acupuncture plus cognitive function training can effectively improve the symptoms of Parkinson's disease dementia.
6.Clinical observation and effects on endocrine of the recipe of invigorating kidney for regulating menstru-ation combined with leptosome in the treatment of polycystic ovary syndrome ovulation disorders
Clinical Medicine of China 2016;32(10):943-946
Objective To determine the recipe of invigorating kidney for regulating menstruation com?bined with curved repairing in the treatment of polycystic ovary syndrome( PCOS) ovulation disorder related out?come measures,and to evaluate the clinical curative effect of the therapy. Methods Sixty?eight cases of PCOS ovulation disorder patients were randomly selected and randomly divided into the pure western medicine treat?ment control group and integrated traditional Chinese and Western medicine treatment of the observation group, each group had 34 cases. The control group patients were given oral progestin capsule with 0. 2 g/time,1 time/d, and continuous oral administration for 10 days,Letrozol tablets began to take on the fifth day of menses,2. 5 mg/time,1 time/d,and continuous oral administration for 5 days. The observation group on the basis of the control group treatment,invigorating kidney for regulating menstruation recipe treatment began to take on the fifth day of menses,daily 1 agent,water frying to 400 ml,2 times a day,and continuous oral administration for 15 days as a cycle of medication,2 groups of patients were treated for 3 courses of treatment. Measurement of two groups be?fore and after treatment in patients with serum luteinizing hormone(LH),follicle stimulation hormone(FSH), LH/FSH ratio,serum testosterone( T) ,estuarial( E2) ,and fasting,meal after 1 and 2 h insulin( INS) levels,and then compared the two groups of patients with follicular maturation rate,the ovulation rate,pregnancy rate and a?bortion rate. Results The LH(t=9. 763,P=0. 003),serum T(t=1. 906,P=0. 023),LH/FSH(t=3. 098,P=0. 026) and fasting insulin(t=5. 973,P=0. 004),postprandial 1H insulin(t=17. 009,P=0. 000),2 h pan?creatic island prime( t=20. 313,P=0. 000) levels of observation group were significantly lower than that of the control group after administration of treatment,while E2(t=121. 1,P=0. 924),FSH(t=0. 879,928) levels of two groups before and after treatment did not change significantly, there was no statistical significance differ?ence. Mature follicles rate,ovulation rate and pregnancy rate of observation group were obviously higher than that of the control group(75. 1% vs. 46. 9%,89. 4% vs. 68. 5%,86. 6% vs. 42. 3%,χ2=10. 635,8. 428,9. 372;P=0. 000),while the abortion rate was significantly lower than that of the control group(10. 2% vs. 20. 3%,χ2=11. 744,P=0. 002). Conclusion The recipe of invigorating kidney for regulating menstruation combined with leptosome in the treatment of polycystic ovary syndrome ovulation has definite curative effect,it is worthy of pro?motion.
7.Clinical studies of Maren capsule and walking exercise as intervention for senile habitual constipation
International Journal of Traditional Chinese Medicine 2017;39(3):218-220
Objective To observe the effect of Maren capsule with walking exercise for the patients with senile habitual constipation in community. Methods A total of 112 patients were randomly divided into three groups (control group A and the intervention group B,C). All the three groups took Maren capsule, and group A did not do the walking exercise, group B and C, walked for 30 min and 60 min after dinner, respectively. Two weeks were one course of treatment, all the groups took two courses. Results After treatment, the constipation symptoms and signs scores (4.1 ± 2.0, 4.8 ± 2.1 vs. 5.3 ± 1.5, F=3.886) in the group B and C were significantly lower than those in the control group A (P<0.05) ); and the scores in the group C was lower than that in the group B (P=0.041). Two weeks after the treatment, total effective rates were 36.8%(14/38), 63.2% (24/38), and 77.8% (28/36) in group A, B, C; and the difference was statistically significant (χ2=12.741, P=0.005). Four weeks later, total effective rates were 47.4%(18/38), 76.3%(29/38), 86.1%(31/36) in group A, B, C; and the difference was statistically significant (χ2=13.103, P=0.005). In the following 2 weeks after the end of treatment, total effective rates were 23.7% (9/38), 60.6% (23/38), 75.0% (27/36) in group A, B, C; and the difference was statistically significant (χ2=12.904, P=0.015). Conclusions The Maren capsule with 60 min walking exersice showed significant effect for the senile habitual constipation.
9.A clinical evaluation of prognosis of severe brain injury using S100B protein
Chinese Journal of Postgraduates of Medicine 2012;35(8):3-5
ObjectiveTo investigate the value of S100B protein in the evaluation of prognosis for patients with severe brain injury.MethodsThe serum S100B protein concentration was determined by enzyme-linked immunosorbent assay in 86 patients with severe brain injury(observation group) and 89 healthy individuals(control group) from February 2009 to March 2011.The clinical symptom and Glasgow outcome scale(GOS) score were measured.ResultsIn the 86 patients of observation group,33 patients were with good-recovery,25 patients were with moderate-deficit,14 patients were with severe-deficit,1 patient was detected of persistent vegetative status,and 13 patients died.The rate of excellent prognosis and worse prognosis were 67.4% (58/86) and 32.6% (28/86).The concentration of S100B protein was obviously higher in observation group [ ( 1.42 ± 0.42 ) μ g/L ] than that in control group [ (0.16 ± 0.05 ) μ g/L ] in 24 hours (P < 0.01 ).The concentration of S100B protein in worse prognosis [ (2.15 ± 0.51 ) μ g/L] was obviously higher than that in excellent prognosis [ ( 0.92 ± 0.49) μ g/L ] ( P < 0.05).ConclusionsS100B protein has high sensitivity and specificity to evaluate brain injury,and it is a reliable and valid biochemical marker of the brain damage.It has important clinical value in the evaluation of severity and prediction of prognosis for patients with severe brain injury.
10.The internal fixation with double steel plate by the olecranon osteotomy approach in the treatment of severe condyle humeral intercondylar splintered fracture
Chinese Journal of Primary Medicine and Pharmacy 2012;19(10):1478-1479
ObjectiveTo explore the effect and surgical management of the internal fixation with double steel plate by the olecranon osteotomy approach in the treatment of severe condyle humeral intercondylar splintered fracture.Methods50 patients with severe condyle humeral intercondylar splintered fractures were treated by double plate internal fixation through olecranon osteotomy.ResultsAll patients(50 cases) were followed up for 6 months to 2 years.The complications such as bone defect,ossifyingmyositis,tardive ulnar nerve compression,and internal fixation fail were not found.According to Aitken Rorabeck scale,the function of the elbow showed excellent in 35 cases,good in 9 cases,fair in 6 cases,the excellent and good rate was 88%.ConclusionThe internal fixation with double steel plate by the olecranon osteotomy approach in the treatment of severe condyle humeral intercondylar splintered fracture was a good approach.Anatomical reduction surgically reconstructed stabilization of the elbow and early active rehabilitation were crucial factors of functional rehabilitation of the elbow.