Objective To explore the clinical feasibility of three-port laparoscopic cholecystectomy(LC).Methods From April 2006 to April 2007,364 patients with acute or chronic cholecystitis underwent LC using three-port method.The clinical data of the patients were analyzed retrospectively.Results All of the 364 patients were cured.Three-port LC were completed in 357 of them with a success rate of 98%.Seven patients were converted to four-trocar LC because of frozen Callot's triangle and gallbladder atrophy.The operation time was 30-80 min(mean,55 min).No severe complications including bile duct injury,bile leakage,and hemorrhage,occurred in our patients.Among the patients who were treated with three-trocar LC,250 were followed up for 1 to 13 months with a mean of 5 months.During the follow-up,no bile duct stenosis,gallbladder pouch,or residual stones were found.Conclusion Three-port LC is safe,effective,and feasible for patients with cholecystitis,if the surgeons have grasped the techniques of four-port LC.

Objective To investigate and find a multiple treatment to reduce the mortality of sepsis patients induced by severe surgical abdominal infection.Methods While treating to severe surgical abdominal infection,inflammatory mediator bacteria,extoxin and endotoxin,immunity,dysfunction of microcirculation,nutrition and metabolism and the function of organs should be paid more attention on and considered as a whole.We also carried out 14 concrete treating measurement.Combined high dosage of anisodaminum and dexamethason were used in sbort-term.Bring forward nourishment support according to different stage of MODS and applying it in clinic could significantly reduce the companion syndrome.Oral administration of“JIE-DU-GU-BEN-TANG”which developed by our division could regulate the imbalance of immunity and inflammatory mediator.Results There were 46 patients died in 368 patients,mortality was 12.50%. Conclusion It was difficult to treat sepsis patients induced by severe abdominal infection and our new multiple treatment could significantly reduce the mortality of severe sepsis.

Objective:To investigate the related factors of postoperative prognosis in patients with gastric cancer.Methods:The clinical and pathological data of 489 patients with gastric cancer,who underwent surgical treatment from Apr 2007 to May 2013 in Wujin Hospital,Jiangsu University were retrospectively analyzed,and the prognosis was evaluated with univariate and multi-variate analysis.Results:In the univariate analysis,age,tumor size,histological type,depth of invasion,operation method,num-ber of lymph node metastasis,carcinoembryonic antigen(CEA)level increases preoperatively,the existence of distant metastasis were found to be significantly associated with the cumulative survival rate(P < 0.05).Multivariate Cox regression analysis showed that histological type,number of lymph node metastasis,preoperative increase of CEA level,existence of distant metas-tasis were the independent factors which affected postoperative outcomes of patients with gastric cancer(P <0.05).Conclu-sions:Histological type,number of lymph node metastasis,existence of distant metastasis and preoperative increase of CEA level are the main factors that affect the postoperative prognosis of patients with gastric cancer.