We analyzed the differences between responder and non-responder groups using Choyoto for hand eczema. In 7 cases the drug was effective, and in 6 cases it was not. Most patients in the effective group had white-complexioned skin, and the eczema tended to localize on the hands. In contrast, most patients in the non-effective group had with sleep difficulties and/or a smoking habit. In addition, they showed marked symptoms of Oketsu such as dark red gingiva, indicating that many of the non-effective hand eczema cases had elevated Oketsu scores. It was shown that objective and subjective symptoms could be indicators for the choosing of Choyoto for hand eczema treatment.

Approximately 40% of women during the course of their menstrual cycles suffer from premenstrual syndrome (PMS). The cause of this syndrome is unknown, furthermore diagnostic criteria and treatments have not been established. Kampo medicines were applied using Kami-shoyo-san as a first choice, and several other alternative Kampo medicines, to 33 PMS patient cases. To evaluate the effectiveness of this therapy, PMS scores were recorded prior to treatment. Patients' scores were recorded as; score 0 (symptomless), score 1 (endurable), score 2 (unbearable without medicine), as well as the five major characteristics of PMS, 1) psychiatric symptoms, 2) headache, 3) breast pain, 4) swelling, 5) lower abdominal pain or lumbago. The scores were verified subsequent to two menstrual cycles. Kampo medicine was found to be effective in 24 cases, with scores declining in average from 4.4 to 1.5. Further treatments were requested in 4 cases, moreover, 5 cases were discounted altogether. Thus Kampo medicine proved to be a very useful method for patients suffering from PMS.