Pulse diagnosis is one of the most important diagnostic method in Chinese medicine, however, the expression of this diagnostic technique is subjective and cannot be in this form compared with modern medicine. Many attempts to describe the pulse conditions objectively have been made, however, there has been little success.
Any wave can be described by the frequency distribution of the energy, according to Fourier. Using this method, we tried to objectify the pulse wave. For the recording of the pulse, a pick-up (Nihon Kohden TF-11S) was fixed in a place at the radial artery and pressure applied using a micromanipulator. The output was put into a data recorder through an amplifier and monitored by an oscillograph. Data was then processed using computer (HITAC-20) and power spectrums were displayed.
In the above described method, the minimum and maximum force which should be applied to detect the pulse wave varied from person to person. The range was from 10-50g and 400-600g for minimum and maximum, respectively. This can be considered as individual variations of so called “floating and sunken” pulses. The best shape of pulse waves were obtained with 100-300g of pressure.
A typical power spectrum of pulse wave was composed of standard sine curve (approximately 1Hz, basic wave) and its harmonics. Sharply peaked waves occured when the basic component was great and oppositely, the flatter waves contained abundant of harmonics. The ratio of the basic wave to its harmonics represents the characteristics of wave pattern, i. e., objective description of pulse conditions can be made.
We will then, investigate the correspondence of the recordings to the expressions in the Chinese medicine, influences of acupuncture, etc.

The purpose of this study was to investigate the relationship between cognitive function and physical performance in Japanese older adults. Ninety four older adults, aged 65 to 87 years (mean age 71.9±5.3 years), were recruited as participants. Cognitive function was evaluated by Five-cognitive Function Test (FCFT). The FCFT, which was developed specially for Japanese older adults, consists of 5 subscale elements: attention, verbal memory, visuospatial cognition, word fluency, and associate learning. Hand dexterity (3 items), muscle strength (2 items), balance (3 items), flexibility (2 items), walking ability (2 items) and reaction ability (2 items) were defined as lifestyle-related physical performances. After adjusting for age, educational level and systolic blood pressure the FCFT score was significantly correlated with observed data of hand dexterity (hand working with a peg board, r=0.485, p<0.001), lower-extremity muscle strength (5-repetition sit-to-stand, r=-0.231, p<0.05), walking ability (5-m habitual walk, r=-0.225, p<0.05; timed up and go r=-0.304, p<0.01), and reaction ability (simple reaction time, r=-0.415, p<0.001; 4-way choice reaction time, r=-0.401, p<0.001). Multiple regression analysis revealed that the FCFT score was explained by the hand working with a peg board (F=42.36, p<0.001) and 4-way choice reaction time (F=29.62, p<0.01). The contribution rate on this model was 42%. These results suggest that cognitive functions were associated with some physical performance. Especially, hand dexterity (hand working with a peg board) and reaction ability (4-way choice reaction time) may be the useful synthetic indicators of cognitive functions in Japanese older adults.

BACKGROUND: Although non-thyroidal illness syndrome (NTIS) is considered a negative prognostic factor, the alterations in free triiodothyronine (fT3) levels in trauma patients requiring massive transfusion have not been reported. METHODS: A prospective observational study comparing 2 groups of trauma patients was conducted. Group M comprised trauma patients requiring massive transfusions (>10 units of packed red blood cells) within 24 hours of emergency admission. Group C comprised patients with an injury severity score >9 but not requiring massive transfusions. Levels of fT3, free thyroxine (fT4), and thyroid-stimulating hormone (TSH) were evaluated on admission and on days 1, 2, and 7 after admission. The clinical backgrounds and variables measured including total transfusion amounts were compared and the inter-group prognosis was evaluated. Results are presented as mean±standard deviation. RESULTS: Nineteen patients were enrolled in each group. In both groups, 32 were men, and the mean age was 50±24 years. In group C one patient died from respiratory failure. The initial fT3 levels in group M (1.95±0.37 pg/mL) were significantly lower than those in group C (2.49±0.72 pg/mL;P<0.01) and remained low until 1 week after admission. Initial inter-group fT4 and TSH levels were not significantly different. TSH levels at 1 week (1.99±1.64 μIU/mL) were higher than at admission (1.48±0.5 μIU/mL) in group C (P<0.05). CONCLUSION: Typical NTIS was observed in trauma patients requiring massive transfusions. When initial resuscitation achieved circulatory stabilization, prognosis was not strongly associated with NTIS.