1.The Application of Modified ChaiShaoBuPi Decoction in the Treatment of Fuctional Dyspepsia
International Journal of Traditional Chinese Medicine 2009;31(3):235-
Objective To study the clinical curative effect of ChaiShaoBuPi decoction in the treatment of functional dyspepsia. Methods 100 patients with functional dyspepsia were divided into a treatment group and a control group randomly. The treaunent group was treated with modified ChaiShaoBuPi decoction and the control group was treated with dornperidone. Both groups were treated for one therapeutic course of four weeks. Results The total effective rate in the treatment group and the control group was 90.00% and 70.00% respectively. The difference between the two groups showed statistical significance (P<0.01) . Conclusion ChaiShaoBuPi decoction has good therapeutic effect in treating the disease of fanctional dyspepsia.
2.The 50 cases clinial observation of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction
International Journal of Traditional Chinese Medicine 2009;31(4):327-
Objective to observe the clinical curative effect of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction. Methods 100 patients suffered peptic ulcer are devided into two groups in random,each for 50. The control group take the western common treatment, the treatment group is based on the control group combination with the Shen-Qi-Jian-Wei decoction made by self.a course of treatment is 50days. Results the total effective power of the control group is 94.0%, the total effective power of the treat group is 72.0%, the total effective power comparision of two groups isobvious,the diffierence has the stastitical meanings.Conclusion the treatment of peptic ulcer based on the Shen-Qi-Jian-Wei decoction made by self is superior to the pure western medicine group.
3.Advance in Nutrition Metabolism of Patients with Spinal Cord Injury (review)
Chinese Journal of Rehabilitation Theory and Practice 2016;22(12):1408-1411
Spinal cord injury (SCI) is a common traumatic disease. SCI causes nutritional and metabolic abnormalities including malnu-trition and overnutrition. This article reviewed nutritional metabolism assessments, the changes and reasons after SCI. Spinal Nutrition Screening Tool (SNST) and Malnutrition Universal Screening Tool (MUST) are commonly used to evaluate malnutrition in adult. Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) is used to evaluate malnutrition in child. Body mass index, waist circumfer-ence and dual-energy X-ray are used to evaluate overnutrition. SCI causes increasement of total caloric intake, disturbance of carbohydrate metabolism, disturbance of fat and protein metabolism, increasement of metabolic syndrome incidence, high risk of coronary heart disease, and abnormal bone metabolism. Individual diet program should be provided to SCI patients for balanced nutrition. Periodic assessments are also necessary.
4.Effect of lidocaine combined with local anesthesia and psychological intervention on induced abortion
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):351-352
Objective To study the effect of lidocaine combined with local anesthesia and psychological intervention in induced abortion.Methods200 cases of artificial abortion in our hospital from March 2015 to August 2016 were selected as the research object and randomly divided into control group and experimental group,with 100 cases in each group.The control group was treated with lidocaine for local anesthesia,direct abortion,and the experimental group was given lidocaine local anesthesia and psychological intervention.The pain and satisfaction index of the two groups were compared.ResultsAfter the treatment, the satisfaction rate of cervical dilatation in the experimental group was 93 cases was 93% higher than that in the control group, and the difference was statistically significant (P<0.05).The number of patients with grade Ⅱ pain in the experimental group was 12, and the number of patients with grade I pain was 87.In the control group, the number of patients with grade Ⅱ pain was 25, and the number of patients with grade Ⅱ pain was 57.But the control group was significantly lower than the experimental group, with statistical difference (P<0.05).In the control group, patients with grade Ⅱ pain were significantly higher than those in the experimental group, the number of patients with grade I pain was significantly less than that in the experimental group, and the difference was statistically significant (P<0.05).There was no significant difference in the operation time and blood loss between the control experimental and the control group.ConclusionThe application of lidocaine local anesthesia combined with psychological intervention can effectively relieve the pain of patients and improve the therapeutic effect.It has the value of clinical popularization and Application.
5.Cost-effectiveness Analysis of Three Anticancer Chemotherapeutic Schemes for Acute Mononuclear Leuk- emia
China Pharmacy 1991;0(04):-
OBJECTIVE:To evaluate the economic effectiveness in different chemotherapeutic schemes for acute mononu?clear leukemia(M 5 ).METHODS:Using pharmacoeconomic cost-effectiveness analysis,three chemotherapy schemes for M 5 we_ re compared.RESULTS:Among three schemes,DAE scheme was the best one.CONCLUSION:The results show that phar?macoeconomics plays an important role in optimizing therapeutic scheme,in helping the physician to choose the best therapeutic plan in making clinical decision.
6.Inhibitory effects of survivin antisense oligonucleotide on human endometrial carcinoma cells
Jinyu XU ; Yaping CHEN ; Bingjin CHEN
Fudan University Journal of Medical Sciences 2009;36(6):723-726
Objective To investigate the effects of survivin antisense oligonucleotide (ASODN) on human uterine endometrial cancer HEC-1B cell line. Methods The experiment included four groups: blank control group (blank), lipofectin control group (Lip), oligonucleotide (SODN) control group and antisense oligonucleotide (ASODN) test group. Artificially synthesized survivin antisense oligonucleotide was transfected for 48 hours into endometrial cancer cells using liposome after cultivation. The expression of survivin protein was determined by Western blot, and the cellular apoptotic rate was tested by flow cytometric analysis. MTT method was used to assay cellular growth rate. Results In comparing with the blank, Lip and SODN control groups, survivin protein expression was obviously decreased in HEC-1B cancer cells after transfected with survivin ASODN. The apoptotic rate and proliferation inhibition rate in ASODN test group were significantly higher than that in the control groups (P<0.05). There was no significant difference between other control groups (P>0.05). Conclusions The expression of survivin is decreased in endometrial cancer cells after ASODN transfection. Survivin ASODN causes cellular apoptosis and inhibits the proliferation of HEC-1B cells. It may be a useful gene therapy for endometrial cancer.
7.Effects of TSPG combined with EPO or GM-CSF on differentiation of K562 cells
Dilong CHEN ; Yaping WANG ; Tingmei CHEN ;
Journal of Third Military Medical University 2003;0(22):-
Objective To investigate the effects of total saponins of Panax ginseng(TSPG) combined with erythropoietin(EPO) or granulocyte macrophage colony stimulating factor(GM CSF) on the differentiation of K562 cells. Methods Cells were cultured in vitro . Morphologic changes of cells were observed with light microscope and electron microscope. The levels of hemoglobin, peroxidase, non specific lipase ? NAE in cells were detected respectively by benzidine staining, peroxidase(POX) staining and ? NAE cytochemical staining. Levels of cell surface differentiation antigens CD15, HIR2, EPO R and GM CSF R were determined by immunocytochemistry. Results TSPG combined with EPO or GM CSF resulted in more mature morphological features of K562, increased expressions of hemoglobin and myeolperoxidase in K562 cells, and enhanced expressions of cell surface differentiation antigens CD15, HIR2, EPO R and GM CSF R. Conclusion TSPG combined with cytokine EPO or GM CSF can induce more mature differentiation of K562 cells.
8.Survey or degree of medical nurse's acute stress disorder from death of cancer patients and its related factors
Qun CHEN ; Yaping ZHENG ; Fengchun ZHANG
Modern Clinical Nursing 2016;15(12):9-13
Objective To study the psychological stress level of medical nurses when the hospitalized cancer patients died and to investigate the related factors.Methods Toally 72 medical nurses on duty who encountered cancer patient's death between May 2013 to November 2015 were enrolled in the study.SCL-90 was used to investigate the mental stress levels in the medical nurses on days 3 and 7 after the patient's death,which were compared with the norm.The correlations between psychological stress level and related factors were studied.Results The score by SCL-90 on day 3 was significantly higher than that on day 7 (147.15±29.09 vs.133.62±20.37,t=6.64,P=0.00).Compared to the norm,the scores on 9 dimensions of SCL-90 were significantly different 3 days after the patient's death;dimensions of SCL-90 were significantly different 7 days after parternt's death (P<0.05).Professional working was factor for medical nurse's acute stress disorder.Conclusion Cancer patients' deaths render huge impact on medical nurses,with acute stress disorder most manifest.In order to improve the the psychological quality of nurses,especially the young and inexperienced ones,we have to enhance the death education,helping them to seek for social support.
9.Research of the effect of hidden blood loss after simultaneous bilateral total knee arthroplasty
Desheng CHEN ; Qunhua JIN ; Yaping LI
Orthopedic Journal of China 2006;0(17):-
[Objective]To study the correlated factors of hidden blood loss after simultaneous bilateral total knee arthroplasty.[Method]From Feb.2005 to Feb.2007,a retrospective analysis of 44 patients underwent knee arthroplasty was conducted to calculate the mean blood loss and occult blood loss according to Gross formula.The true total blood loss was calculated depending on height weight and pre-and post-operation HCT.[Result]The mean total blood loss were 2 065 ml in these cases with occult blood loss of 1 198 ml.In patients with autologous blood transfusion,the mean total blood loss were 2 180 ml with occult loss of 937 ml(42%).In patients without autologous blood transfusion,the mean total blood loss were 1 195 ml with occult blood loss of 799 ml(41%).[Conclusion]The hidden blood loss result in large volume of the total blood loss in the postoperative period which can not be fully compensated by autologous blood transfusion and it 's very important to additional blood supply during simultaneous bilateral total knee arthroplasty.
10.Relationship between parathyroid hormone changes in patients with chronic renal failure and cerebrovascular events
Yaping JIANG ; Hailong CHEN ; Min YANG
Chinese Journal of Primary Medicine and Pharmacy 2010;17(17):2332-2333
Objective To investigate the relationship of iPTH levels, calcium and phosphorus metabolism with cardiovascular event status in the chronic renal failure (CRF) patients. Methods This article retrospectivly studied the clinical and laboratory data of 87 CRF patients. 66 patients of A group didnt occur cardiovascular events,and 21 cases of B group occurred cardiovascular and cerebrovascular events. This article analyzed iPTH levels,serum calcium, phosphorus, calcium and phosphorus product and therelationship between cardiovascular and cerebrovascular events between the two groups. Results Decreased iPTH,increased serum C reactive protein and increased lipoprotein(a) had relationship with cardiovascular and cerebrovascular events in patients with chronic renal failure,but calcium,phosphorus,calcium and phosphorus product has nothing to do with the cardiovascular and cerebrovascular events. Cardiovascular and cerebrovascular events increased significantly in dialysis patients than in non - dialysis patients. Conclusiou Chronic renal failure patients on dialysis levels of serum iPTH, CRP level, LP(a) level and dialysis could lead to cardiovascular and cerebrovascular events.