1.The Application of Modified ChaiShaoBuPi Decoction in the Treatment of Fuctional Dyspepsia
International Journal of Traditional Chinese Medicine 2009;31(3):235-
Objective To study the clinical curative effect of ChaiShaoBuPi decoction in the treatment of functional dyspepsia. Methods 100 patients with functional dyspepsia were divided into a treatment group and a control group randomly. The treaunent group was treated with modified ChaiShaoBuPi decoction and the control group was treated with dornperidone. Both groups were treated for one therapeutic course of four weeks. Results The total effective rate in the treatment group and the control group was 90.00% and 70.00% respectively. The difference between the two groups showed statistical significance (P<0.01) . Conclusion ChaiShaoBuPi decoction has good therapeutic effect in treating the disease of fanctional dyspepsia.
2.The 50 cases clinial observation of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction
International Journal of Traditional Chinese Medicine 2009;31(4):327-
Objective to observe the clinical curative effect of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction. Methods 100 patients suffered peptic ulcer are devided into two groups in random,each for 50. The control group take the western common treatment, the treatment group is based on the control group combination with the Shen-Qi-Jian-Wei decoction made by self.a course of treatment is 50days. Results the total effective power of the control group is 94.0%, the total effective power of the treat group is 72.0%, the total effective power comparision of two groups isobvious,the diffierence has the stastitical meanings.Conclusion the treatment of peptic ulcer based on the Shen-Qi-Jian-Wei decoction made by self is superior to the pure western medicine group.
3.Clinical study of flare-up after root canal therarp on acute periapical periodontitis
Journal of Chongqing Medical University 1986;0(03):-
Objective:To evaluate the incidence pain after treatment of acute periapical periodontitis using calcium hydroxide and CP as an intracanal dressing at the first time.Methods:303 patients with single-root acute periapical periodontitis were randoml allocated to three groups.A group was treated by stainless steel hand files and opened;B group was treated by stainless steel hand files and covered by CP.;C group was treated with Hero nickel-titanium rotary instruments and covered by calcium hydroxide paste.The incidence and degree of incidence pain after root canal preparation in the three groups were recorded.Results:There were significant difference between group A and group B,group B and group C,group A and group C(P
4.Clinical study of ligustrazine combined with phentolamine in the treatment of pregnancy induced hypertension
Chinese Journal of Primary Medicine and Pharmacy 2017;24(19):3002-3005
Objective To investigate the effect of ligustrazine combined with phentolamine in the treatment of pregnancy induced hypertension.Methods 90 patients with pregnancy induced hypertension were randomly divided into the observation group and the control group according to the random number table,45 cases in each group.The control group was treated with phentolamine and magnesium sulfate.The observation group was given Chuanqiongqin injection,phentolamine and magnesium sulfate for 10 days.The effects of the two groups were compared before and after treatment,and the changes of mean arterial pressure,24h urine protein and perinatal adverse reaction were compared.Results After treatment,the mean arterial pressure [(99.7 ± 36.2) mmHg vs.(108.4 ± 35.1) mmHg] and 24h urinary protein [(1.41 ± 0.45)g/L vs.(2.51 ± 0.82)g/L] were significantly decreased in the two groups.Compared with before treatment,the differences were statistically significant (t =3.534,3.765,5.646,6.543,all P < 0.05).And the improvement of the observation group was significantly better than those of the control group,the differences were statistically significant (t =3.365,3.986,all P < 0.05).The cure rate (71.1% vs.44.4%) and total effective rate (95.6% vs.82.2%) in the observation group were higher than those in the control group,the differences were statistically significant (x2 =6.559,4.050,all P < 0.05).The rate of termination of pregnancy of the observation group was significantly lower than that of the control group(40.0% vs.62.2%),the incidence rates of premature delivery (2.2% vs.15.6%) and postpartum hemorrhage(6.7% vs.22.2%) of the observation group were significantly lower than those of the control group,the proportion of neonatal asphyxia (4.4% vs.17.8%) of the observation group was lower than that of control group,the differences were statistically significant (x2 =4.447,4.939,4.406,4.050,all P < 0.05).Conclusion Ligustrazine combined with phentolamine in the treatment of pregnancy induced hypertension can significantly improve the average arterial pressure and 24h urinary protein,has good efficacy,less adverse reactions during perinatal period.
5.Observation on the effects of calcium dobesilate on serum Hs-CRP, TNF-α levels and kidney function in patients with maintenance hemodialysis
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):250-251
Objective To explore the use of maintenance hemodialysis patients in the application of calcium dobesilate on serum Hs-CRP and TNF-α and renal function. Methods 86 patients with maintenance hemodialysis admitted from Xiangyang Central Hospital from October 2015 to November 2016 were divided into 43 patients according to the treatment group and 43 patients in each group. The control group Given conventional hemodialysis treatment, the study group on the basis of the control group given calcium benzenesulfonate treatment, and finally the results of the two groups of patients to statistics and summary. Results Before treatment, the difference of BuN, Scr, Hs-CRP and TNF-α between the study group and the control group was not statistically significant. The scores of BuN, Scr, Hs-CRP and TNF-α in the study group and the control group were significantly higher than those in the control group (P<0.05), and the difference was statistically significant (P<0.05). The serum Hs-CRP and TNF-α in the study group were significantly lower than those in the control group (P<0.05). Conclusion Calcium dobesilate can reduce BuN and Scr, improve renal function, reduce Hs-CRP, TNF-α and improve microinflammation. Patient side effects, improve survival, To improve the quality of life.
7.Strengthen advancement of tumor tendency and earlier diagnostic technology
Chinese Journal of Laboratory Medicine 2003;0(11):-
The latest advancement on tumor biology and tumorigenesis has been discussed in this paper. The potential clinical significance on tumor tendency and early diagnosis of the genomic and proteomic analysis technology has been expounded too. It will be benefit for the new tumor biomarker studies.
8.Serum immunoglobulin free light chain analysis for identifying and monitoring patients with multiple myeloma and related disorders
Chinese Journal of Practical Internal Medicine 2000;0(11):-
The serum immunoglobulin-free light chain (FLC) assay measures levels of free ? and ? immunoglobulin light chains and is an invaluable tool in the evaluation and management of multiple myeloma and related plasma cell disorders (PCD).The serum FLC assay in combination with serum protein electrophoresis (SPEL) and immunofixation yields high sensitivity of screening,and negates the need for 24 h urine studies for diagnoses other than light chain amyloidosis (AL).The baseline FLC measurement is of major prognostic value in virtually every PCD.The FLC assay allows for quantitative monitoring of patients with oligosecretory PCD,including AL,oligosecretory myeloma and non-secretory myeloma.In AL patients,serial FLC measurements outperform SPEL and immunofixation.
9.Progress in the application of infliximab in Kawasaki disease
International Journal of Pediatrics 2015;42(6):666-668,672
Kawasaki disease is an acute and self-limited systemic vasculitis.Coronary artery lesions are the most common complications.The principal treatment with intravenous immunoglobulin and high doses of oral aspirin has significantly decreased the morbidity of coronary artery lesions.However, increased cases of IVIG non-responsiveness and refractory Kawasaki disease in recent years make the treatment more difficult.The existing progress indicates that infliximab provides a new therapeutic option for Kawasaki disease, especially for IVIG non-responsiveness and refractory Kawasaki disease.This paper reviews recent studies associated with application of infliximab in Kawasaki disease.
10.Comparison of the results between transcranial Doppler ultrasonography and CT examination of patients with transient ischemic attack
Chinese Journal of Tissue Engineering Research 2005;9(25):194-195
BACKGROUND: Transient ischemic attack is a risk factor in the causation of complete stroke. Early detection of transient ischemic attack by the examinations of imaging and ultrasonography together with timely interventions can prevent it from developing to complete stroke.OBJECTIVE: To compare the values of early transcranial Doppler ultrasonography and CT examination in the evaluation of early transient ischemic attack.DESIGN: A case analysis.SETTING: Department of Neurology, CT Room and Transcranial Doppler Ultrasonography Room in a municipal hospital.PARTICIPANTS: Thirty in- and out-patients with transient ischemic attack (22 males and 8 females), at the age of 26 to 85 with an average of 59.6 years old in the Yuanbaoshan District Hospital of Chifeng City between January 2001 and April 2003 were involved in the study.INTERVENTIONS: After admission, all the 30 patients with transient ischemic attack were given routine lose of medication for promoting blood circulation and invigorating pulse-beat, and heparin or low molecular hepacarin calcium; Cranial CT examination was performed for all selected patients, and the transcranial Doppler ultrasonic diagnostic system was also used to detect the related dynamic parameters of systolic and diastolic flow rate, mean flow velocity and pulse index of bilateral internal carotid artery and vertebral basilar artery. The occurrence of cerebral infarction was observed through follow up for 1 month and 1 year.MAIN OUTCOME MEASURES: ① Results of cranial CT examination;② Results of transcranial Doppler ultrasonography; ③ The occurrence of cerebral infarction in the 30 patients after follow up for 1 month and 1 year.RESULTS: All the 30 patients were followed up for 1 month and I year after discharge. ① Focal changes were detected with CT examination in 10 cases (34%, 10/34); ② Abnormal changes of hemorheology were detected with transcranial Doppler ultrasonography in 24 cases (80%, 24/30). ③ Among the 30 patients treated with heparin or low molecular hepacarin calcium, cerebral infarction occurred in 4 cases within 1 month, and 6 cases between 1 month and 1 year.CONCLUSION: For patients with transient ischemic attack, the hemorheological abnormality can be detected earlier with transcranial Doppler ultrasonography than with CT examination; treatment for anti-coagulation should be given as early as possible after the transient ischemic attack to reduce the reoccurrence rate and prevent the occurrence of complete stroke.