Objective:To evaluate the incidence pain after treatment of acute periapical periodontitis using calcium hydroxide and CP as an intracanal dressing at the first time.Methods:303 patients with single-root acute periapical periodontitis were randoml allocated to three groups.A group was treated by stainless steel hand files and opened;B group was treated by stainless steel hand files and covered by CP.;C group was treated with Hero nickel-titanium rotary instruments and covered by calcium hydroxide paste.The incidence and degree of incidence pain after root canal preparation in the three groups were recorded.Results:There were significant difference between group A and group B,group B and group C,group A and group C(P

Objective to observe the clinical curative effect of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction. Methods 100 patients suffered peptic ulcer are devided into two groups in random,each for 50. The control group take the western common treatment, the treatment group is based on the control group combination with the Shen-Qi-Jian-Wei decoction made by self.a course of treatment is 50days. Results the total effective power of the control group is 94.0%, the total effective power of the treat group is 72.0%, the total effective power comparision of two groups isobvious,the diffierence has the stastitical meanings.Conclusion the treatment of peptic ulcer based on the Shen-Qi-Jian-Wei decoction made by self is superior to the pure western medicine group.

Kawasaki disease is an acute and self-limited systemic vasculitis.Coronary artery lesions are the most common complications.The principal treatment with intravenous immunoglobulin and high doses of oral aspirin has significantly decreased the morbidity of coronary artery lesions.However, increased cases of IVIG non-responsiveness and refractory Kawasaki disease in recent years make the treatment more difficult.The existing progress indicates that infliximab provides a new therapeutic option for Kawasaki disease, especially for IVIG non-responsiveness and refractory Kawasaki disease.This paper reviews recent studies associated with application of infliximab in Kawasaki disease.

The serum immunoglobulin-free light chain (FLC) assay measures levels of free ? and ? immunoglobulin light chains and is an invaluable tool in the evaluation and management of multiple myeloma and related plasma cell disorders (PCD).The serum FLC assay in combination with serum protein electrophoresis (SPEL) and immunofixation yields high sensitivity of screening,and negates the need for 24 h urine studies for diagnoses other than light chain amyloidosis (AL).The baseline FLC measurement is of major prognostic value in virtually every PCD.The FLC assay allows for quantitative monitoring of patients with oligosecretory PCD,including AL,oligosecretory myeloma and non-secretory myeloma.In AL patients,serial FLC measurements outperform SPEL and immunofixation.

The latest advancement on tumor biology and tumorigenesis has been discussed in this paper. The potential clinical significance on tumor tendency and early diagnosis of the genomic and proteomic analysis technology has been expounded too. It will be benefit for the new tumor biomarker studies.

Objective To investigate the effect of ligustrazine combined with phentolamine in the treatment of pregnancy induced hypertension.Methods 90 patients with pregnancy induced hypertension were randomly divided into the observation group and the control group according to the random number table,45 cases in each group.The control group was treated with phentolamine and magnesium sulfate.The observation group was given Chuanqiongqin injection,phentolamine and magnesium sulfate for 10 days.The effects of the two groups were compared before and after treatment,and the changes of mean arterial pressure,24h urine protein and perinatal adverse reaction were compared.Results After treatment,the mean arterial pressure [(99.7 ± 36.2) mmHg vs.(108.4 ± 35.1) mmHg] and 24h urinary protein [(1.41 ± 0.45)g/L vs.(2.51 ± 0.82)g/L] were significantly decreased in the two groups.Compared with before treatment,the differences were statistically significant (t =3.534,3.765,5.646,6.543,all P ＜ 0.05).And the improvement of the observation group was significantly better than those of the control group,the differences were statistically significant (t =3.365,3.986,all P ＜ 0.05).The cure rate (71.1％ vs.44.4％) and total effective rate (95.6％ vs.82.2％) in the observation group were higher than those in the control group,the differences were statistically significant (x2 =6.559,4.050,all P ＜ 0.05).The rate of termination of pregnancy of the observation group was significantly lower than that of the control group(40.0％ vs.62.2％),the incidence rates of premature delivery (2.2％ vs.15.6％) and postpartum hemorrhage(6.7％ vs.22.2％) of the observation group were significantly lower than those of the control group,the proportion of neonatal asphyxia (4.4％ vs.17.8％) of the observation group was lower than that of control group,the differences were statistically significant (x2 =4.447,4.939,4.406,4.050,all P ＜ 0.05).Conclusion Ligustrazine combined with phentolamine in the treatment of pregnancy induced hypertension can significantly improve the average arterial pressure and 24h urinary protein,has good efficacy,less adverse reactions during perinatal period.

Objective To analyze the application effect on gynecological laparoscopic surgery patients by different dexmedetomidine doses.Methods One hundred gynecological laparoscopic surgery patients were divided into control group and observation group by random digits table method with 50 cases each.The patients in observation group were given dexmedetomidine 0.5 μ g/kg intravenous injection 15 min before induction of anesthesia intubate,the patients in control group were given dexmedetomidine 1.0 μ g/kg,then 0.4 μ g/(kg· min) continuing venous pumping.The induction of anesthesia program in the 2 groups was midazolam,fentanyl citrate,propofol,cisatracurium besilate intravenous injection,maintaining intraoperative depth of anesthesia program was remifentanil and propofol by continuing venous pumping,and the maintaining muscle relaxation program was cisatracurium besilate interruptable injection.The patients in the 2 groups were given dezocine 0.1 mg/kg intravenous injection 30 min before the end of operation.The man-machine system engineering (MMSE) score,restlessness degree (using restlessness score),sedation effect (using Ramsay sedation score),analepsia time,extubation time and drug adverse reaction were compared.Results The rates of postoperative cognitive dysfunction and drug adverse reaction in observation group were significantly lower than those in control group [10％(5/50) vs.32％(16/50),10％(5/50) vs.40％(20/50)],Ramsay sedation score,analepsia time and extubation time were significantly lower than those in control group [(1.04 ± 0.59) scores vs.(4.84 ± 0.63) scores,(20.14 ± 4.32) min vs.(26.57 ± 4.28) min,(20.17 ± 4.23) min vs.(27.26 ± 4.34) min],there were statistical differences (P ＜ 0.05).There was no statistical difference in MMSE score before anesthesia and 24 h after anesthesia between the 2 groups (P ＞ 0.05),but MMSE score 1,6,12 h after anesthesia in observation group was significantly higher than that in control group [(23.93 ±3.51) scores vs.(20.34 ±3.45) scores,(25.87 ±4.46)scores vs.(21.34 ±4.63) scores,(27.53 ± 4.22) scores vs.(23.49 ± 4.31) scores],there was statistical difference (P ＜ 0.05).Conclusions Dexmedetomidine in accordance with 0.5 μ g/kg can reduce the incidence of postoperative drug cognitive dysfunction in the patients after gynecological laparoscopic surgery,it has good calming effect and less adverse reactions.It is worthy of popularization and application in the clinical work.

BACKGROUND: Transient ischemic attack is a risk factor in the causation of complete stroke. Early detection of transient ischemic attack by the examinations of imaging and ultrasonography together with timely interventions can prevent it from developing to complete stroke.OBJECTIVE: To compare the values of early transcranial Doppler ultrasonography and CT examination in the evaluation of early transient ischemic attack.DESIGN: A case analysis.SETTING: Department of Neurology, CT Room and Transcranial Doppler Ultrasonography Room in a municipal hospital.PARTICIPANTS: Thirty in- and out-patients with transient ischemic attack (22 males and 8 females), at the age of 26 to 85 with an average of 59.6 years old in the Yuanbaoshan District Hospital of Chifeng City between January 2001 and April 2003 were involved in the study.INTERVENTIONS: After admission, all the 30 patients with transient ischemic attack were given routine lose of medication for promoting blood circulation and invigorating pulse-beat, and heparin or low molecular hepacarin calcium; Cranial CT examination was performed for all selected patients, and the transcranial Doppler ultrasonic diagnostic system was also used to detect the related dynamic parameters of systolic and diastolic flow rate, mean flow velocity and pulse index of bilateral internal carotid artery and vertebral basilar artery. The occurrence of cerebral infarction was observed through follow up for 1 month and 1 year.MAIN OUTCOME MEASURES: ① Results of cranial CT examination;② Results of transcranial Doppler ultrasonography; ③ The occurrence of cerebral infarction in the 30 patients after follow up for 1 month and 1 year.RESULTS: All the 30 patients were followed up for 1 month and I year after discharge. ① Focal changes were detected with CT examination in 10 cases (34%, 10/34); ② Abnormal changes of hemorheology were detected with transcranial Doppler ultrasonography in 24 cases (80%, 24/30). ③ Among the 30 patients treated with heparin or low molecular hepacarin calcium, cerebral infarction occurred in 4 cases within 1 month, and 6 cases between 1 month and 1 year.CONCLUSION: For patients with transient ischemic attack, the hemorheological abnormality can be detected earlier with transcranial Doppler ultrasonography than with CT examination; treatment for anti-coagulation should be given as early as possible after the transient ischemic attack to reduce the reoccurrence rate and prevent the occurrence of complete stroke.

Glyeated hemoglobin is a widely used important test in the diagnosis and management of Diabetes Mellitus.Although the Reference Measurement System,Traceability and Clinical for HbA1c have reached international consensus,there are still quite a few aspects related with its clinical and laboratory measurement needed further research.

Objective To explore the effect of mental intervention on mental status and survival quality of patients with cervical cancer. Methods 100 patients with cervical cancer were allocated into the observation group and the control group randomly with 50 patients in each group. Routine care was car-ried out in the control group, besides this, mental intervention was given to the intervention group. The ef-fect of mental intervention on mental status and survival quality of patients were observed and went through t test and χ2 test. Results After intervention, anxiety,depression and pain degree of the observation group was lower than that of the control group, body functions, role functions,mood functions,social functions,the-total life quality were significantly higher than those of the control group. Conclusions Mental interven-tion can improve mental status of patients with cervical cancer, and promote their life quality.