Objective To study the effects of platelet to lymphocyte ratio and D-dimer to fibrinogen ratio combined with WELLS score on the prediction of lower extremity deep vein thrombosis in young cerebral hemorrhage (YCH) patients.Methods One hundred and nine YCH patients in our hospital were divided into thrombus group (33 cases) and non-thrombus group (76 cases).The diagnostic value of PLR and DFR combined with WELLS score was evaluated by areas under the curve (AUC),sensitivity and specificity of receiver operating characteristic curve (ROC).Results PLR,DFR and WELLS score of thrombus group were (149.20±52.17),(118.46±8.37) and (2.67±0.48) respectively,and those of non-thrombus group were (95.27±29.48),(75.28±10.16) and (0.72±0.34) respectively,the differences were statistically significant (P<0.05).The sensitivity,specificity,missed diagnosis rate and misdiagnosis rate were 97.65%,92.43%,2.35% and 7.57%,respectively.AUC value of area under ROC curve was 0.951 (P<0.05).Conclusion PLR,DFR combined with WELLS score has high specificity in predicting LDVTE in YCH patients,and the missed diagnosis rate and misdiagnosis rate are low.It has good clinical practical value and is worthy of popularization and application.