1."Preliminary research in construction of ""school-community"" health education network"
Yuchun ZHOU ; Minxia PAN ; Yaohua YU ; Rufang JI ; Peipei ZHOU
Chinese Journal of Practical Nursing 2013;29(30):1-4
Objective By discussion on the construction of school-community health education network,we can identify suitable community practice ways of improving students' comprehensive ability,enrich community health teams and meet the health demand of community residents.Methods Take Grade 08 and Grade 09 as the test classes.Two classes were selected from each grade,one class was set as the experimental group,the other was named as the control group.The communication skills,critical thinking skills,teamwork skills and the ability of getting the specific knowledge after the community practice for a year were compared between the two groups in each grade separately.At the same time,we assessed the community residents from the following four aspects,knowing about the health information,residents' health beliefs,their change in attitude,their adoption of healthy behaviors,and compared their knowledge of health information about three diseases.Results The results showed that the four mentioned abilities of the experimental groups were significantly improved.The community residents' health information awareness rate after the health education was significantly different compared with that before.There was no significant difference among three other levels.Conclusions Construction of school-community health education network can improve the students' comprehensive quality,it is beneficial to the survival and the development of health schools,and it can meet the needs of community residents,enrich the community health service team,and can also promote the change of teaching ideas.
2.Clinical efficacy of early right median nerve electrical stimulation for coma patients followingcraniocerebral trauma
Guoyi GAO ; Yinghui BAO ; Yumin LIANG ; Yaohua PAN ; Shenghao DING ; Jiyao JIANG
Chinese Journal of Trauma 2012;28(3):200-204
ObjectiveTo evaluate the clinical benefits of early right median nerve electrical stimulation on coma patients following craniocerebral trauma. MethodsCraniocerebral trauma patients with up to two weeks of coma in the years 2005-2011 were involved in the study and were randomly divided into control group (received routine management ) and treatment group (routine management plus right median nerve electrical stimulation).The treatment lasted for a period of more than two weeks.The clinical efficacy of the right median nerve electric stimulation and the conscious status of the patients within six months after craniocerebral trauma were observed.ResultsA total of 456 patients were enrolled in the study,of whom 437 patients completed the treatment course,including 221 patients in the treatment group and 216 in the control group.There was no complication related to electric stimulation during the treatment.Cerebral blood flow (CBF) imaging and brain stem evoked potential (BEP) examination demonstrated significant improvement in the treatment group.A total of 386 patients were followed up for six months postoperatively,which showed that there were 122 patients with regained consciousness,46 in minimally conscious state and 36 in vegetative state in the treatment group (204 patients) and there were 84 patients with regained consciousness,40 in minimally conscious state and 58 in vegetative state in the control group ( 182 patients).The patients in the treatment group showed a higher ratio of regained consciousness and a lower ratio of vegetative state compared with the control group,but the ratio of minimally conscious state showed no statistical difference between two groups. ConclusionsRight median nerve electrical stimulation is a suitable coma awaking means at early stage after craniocerebral trauma.
3.Efficacy analysis of endovascular stenting for aortic arch artery stenosis after nasopharyngeal carcinoma radiotherapy
Xiaoming YIN ; Jieqing WAN ; Yiling FAN ; Yaohua PAN ; Shenghao DING ; Lei CHEN ; Jiyao JIANG
Chinese Journal of Cerebrovascular Diseases 2014;(4):196-200
Objective To investigate the efficacy of endovascular stenting for aortic arch artery stenosis after nasopharyngeal carcinoma radiotherapy. Methods The clinical data of 8 patients with symptomatic severe aortic arch artery stenosis after nasopharyngeal carcinoma radiotherapy were analyzed retrospectively. The patients were all received endovascular stenting,and their improvement of cerebral ischemic symptoms was observed. They were followed up by cervical color Doppler ultrasound.Results The whole brain vascular DSA confirmed that there were 24 severe arterial stenoses on the aortic arch arteries of extracranial segments in 8 patients,including 11 in internal carotid artery,2 in common carotid artery,10 in vertebral artery and 1 in subclavian artery. The patients were treated with vascular angioplasty and stenting respectively. All the patients were followed up for 1 year;there were no recurrence of cerebral ischemic symptoms.Cervical color Doppler ultrasound did not reveal any obvious restenosis. Conclusion Endovascular stent angioplasty for the treatment of aortic arch artery stenosis after nasopharyngeal carcinoma radiotherapy is relatively safe and feasible.
4.Microarray analysis of altered gene expression profile of hippocampus after traumatic brain injury in rats
Junfeng FENG ; Kuiming ZHANG ; Xian FU ; Guoyi GAO ; Yinghui BAO ; Yumin LIANG ; Yaohua PAN ; Jiyao JIANG
Chinese Journal of Trauma 2008;24(5):360-366
Objective To screen the altered gene expression profile of hippocampus after traumatic brain injury(TBI)in rats. Methods Rats(n=3)in experimental group underwent moderate fluid-percussion(F-P)brain injury and the hippoeampus sample in the injured hemisphere was removed and conserved in liquid nitrogen three hours later.The rats(n=5)of the control group underwent the same procedure except for injury.Mfymetrix rat genome 230 2.0 array was used to detect the gene expression profile of hippocampus in two groups and find the altered gene expression profile. Results A total of 159 genes in the experimental group changed significantly(≥2 folds)compared with the control group,of which 136 genes were up-regulated and 23 genes down-regulated. Conclusions The significant gene expression changes of hippocampus,especially a large mount of up-regulated genes,are detected after moderate TBI in rats,suggesting that the secondary injury following TBI is a procedure involving multiple factors.
5.Determination of three chemical constituents in zhuang medicine Blumea megacephala (Randeria) by HPLC.
Xiaoqing NING ; Yaohua LI ; Yuanfeng TAN ; Yong CHEN ; Yan HUANG ; Fuqi PAN
China Journal of Chinese Materia Medica 2011;36(12):1623-1625
OBJECTIVETo develop an HPLC method for content determination of protocatechuic acid, chlorogenic acid and caffeic acid in Zhuang medicine Blumea megacephala (Randeria), and explore the content variation of the 3 components of the herbs harvesting in different months, and provide the scientific basis of reasonable application.
METHODThe determination was carried out on a Shimadzu VP-ODS column (4.6 mm x 250 mm, 5 microm) eluted with acetonitrile and water containing 0.1% phosphoric acid in a linear gradient elution. The flow rate was 1 mL min(-1), and the detected wavelength was set at 258, 327nm.
RESULTThe peak areas and the concentrations of the three components had good linear relationship in the range of 1.7-17 mg x L(-1) for protocatechuic acid, 15.6-156 mg x L(-1) for chlorogenic acid, 3.96-39.6 mg x L(-1) for caffeic acid. The average recoveries were 103.4%, 102.2%, 98.5%, respectively.
CONCLUSIONThe method was proved to be simple, accurate and used for the quality evaluation of Blumea megacephala (Randeria).
Asteraceae ; chemistry ; Caffeic Acids ; chemistry ; Chlorogenic Acid ; chemistry ; Chromatography, High Pressure Liquid ; methods ; Drugs, Chinese Herbal ; chemistry ; Hydroxybenzoates ; chemistry ; Plants, Medicinal ; chemistry
6. Epidemiological investigation of 511 adult inpatients with gas burns
Youfen FAN ; Cui CHEN ; Yanyan PAN ; Shengyong CUI ; Neng HUANG ; Jiliang LI ; Pei XU ; Yaohua YU
Chinese Journal of Burns 2020;36(1):58-63
Objective:
To analyze the epidemiological characteristics of adult inpatients with gas burns in the Department of Burns of Hwa Mei Hospital of University of Chinese Academy of Sciences (hereinafter referred to as the author′s unit) , so as to provide evidence for the prevention of gas burn.
Methods:
Medical records of all inpatients with flame burns admitted to the author′s unit from January 2011 to December 2017 were collected. The percentage of adult inpatients with gas burns in total inpatients with flame burns in the same period, and their gender, age, injury season, accident place, burn severity, common compound injury, complication, population caliber, education, industry, as well as the pre-injury disease and prognosis of elderly inpatients with gas burns were retrospectively analyzed. In addition, the age, accident place, education, and industry of the floating population in the adult inpatients with gas burns were analyzed separately and compared with the total population of adult inpatients with gas burns in 7 years. Data were processed with chi-square test or Fisher′s exact probability test (Monte Carlo algorithm).
Results:
During the 7 years, 1 490 inpatients with flame burns were admitted to the author′s unit, among which 511 were adult inpatients with gas burns, accounting for 34.30%. The number of adult inpatients with gas burns increased gradually during the 7 years, but its percentage in the total inpatients with flame burns during the same period showed no significant difference (