Objective To evaluate the sensitivity and specificity of a rapid one-step test for the detection of Helicobacter pylori antigen in stool samples. Methods 13C-urea breath test (13C-UBT) and rapid urease being taken as “gold standard”, Helicobacter pylori stool antigen (HpSA) was detected with Atlas rapid one-step test among patients with syndromes in upper alimentary tract. These patients were divided into two groups. One was pretreatment group that included 62 cases and the other one was post-treatment group with 42 cases. Results In pretreat_ment group, there were 24 Hp positive cases and 38 negative ones according to the golden standard, 27 positive and 35 negative according to one-step HpSA assay, and the sensitivity and specificity was 100% and 92% respectively; In post-treatment group, 15 positive and 27 negative according to the golden standard, 19 positive and 23 negative according to one-step HpSA assay, and the sensitivity and specificity 93%and 81% respectively; the total sensitivity and specificity was 97% and 88% respectively. Conclusions HpSA rapid one-step test has good sensitivity and specificity in diagnosis of Hp infection and judgment of Hp eradication.

Objective To investigate the protective effect and mechanism of Ziyinmingmuwan on retina against photic injury. Methods Seventy Sprague-Dawley (SD) rats were randomly divided into 7 groups, with 6 groups prepared as the models of phototrauma at first and another group taken as blank control. After three days, the animals in the treatment and control groups were treated with Ziyinmingmuwan and control agent respectively for 15 days during the period of experiment. Following this, the retinal tissues were examined by light and electron microscopy. Results The retinal lesions were repaired and the morphological structure of the retina was brought to normal gradually. Conclusion Ziyinmingmuwan could improve ultrastructure of the retina.