Objective To explore the relationship between personality and mental status of inpatients in the department of neurology of general hospital.Methods 150 inpatients in the department of neurology had been surveyed by Eysenck Personality Questionnaire(EPQ) and Symptom Checklist-90(SCL-90) with the domestic norm as control.Results The examining results of the inpatients in the department of neurology were as following.The scores of neurotisim(N) of EPQ were higher than that of the domestic norm(P<0.05);the scores of extra-introversion(E) and psychoticism(P) of EPQ were lower than that of the domestic norm(P<0.05).The scores of 7 factors including total scores,somatisation,depression,anxiety,hostility,panic and psychosis in SCL-90 were higher than that of the domestic norm( P<0.05).The N scores of EPQ was positively correlated with all factors of SCL-90,the E scoers of EPQ was positively correlated with hostility and paranoia factor of SCL-90,the P scores of EPQ was positively correlated with paranoia factor of SCL-90.Conclusion The mental characteristics of inpatient in the department of neurology of general hospital in acute period are that the incidence of somatisation,depression,anxiety,panic and psychosis are higher than normal people,compulsion and paranoia are as well as normal people.The character of neurotisim and introversion may be the personality background of it.

Objective　To explore the expression of Fas ligan d (FasL) protein in human non-small cell lung cancer (NSCLC) and its clinic al significance. Methods　Expression of FasL protein was detecte d by immunohistochemical method in 32 resected tumors of NSCLC. Results 　FasL protein was detected in all of these 32 resected tumors with variant pos itive expression levels ranging from 3.0% to 98.7% ［mean (62.0±32.0)%］. T here wa s significant difference between the tumors of different pathological types no s ignificant difference was found between the tumors of different differentiation nor among the tumors of different pTNM stages (P>0.05). Conclusion　 The results indicated that NSCLC can counterattack the immune cells of t he body and may be the molecular basis for the easily metastasis of adenocarcino ma to in the early stage.

Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in esophagus surgery. Methods From 1982 to 2010, patients with unspecific chest pain and undergone esophageal surgery were received esophageal manometry and 24-hour pH monitoring. Results Among the patients with unspecific chest pain, 70.4%(74/105) were diagnosed as esophageal origin. Lower esophageal sphincter pressure (LESP) can be continuously maintained by using 360° fundoplication. Only a minority of patients who underwent transabdominal esophagocardiomyotomy and partial posterior fundoplication had acid reflux postoperatively. Incidence rate of achalasia of upper esophageal sphincter (UES) and pharyngeal "shoulder wave" in side-to-side stapled anastomosis is significantly lower than in traditional hand-sewn anastomosis,as well as contractive pressure in anastomosis region and occurrence of swallow discomfortableness. There is a high pressure region at the esophageal entrance in patients with bilateral platysma muscle flap for cervical esophagus defect following removal of hypopharynx cancer. And the pressure of the region is significantly lower than in healthy controls. Basal pyloric pressure and peak pressure of pylorus in phase Ⅲ of the migrating motor complex increased significantly after gastric conduit was made and anastomosed, but decreased appreciably following pyloric digital fracture. Peak pressure, frequency and duration time of isolated pyloric pressure wave ( IPPW ) decreased after pyloric digital fracture significantly. Conclusion Esophageal manometry and 24-hour pH monitoring are important tools for and diagnosing unspecific chest pain and evaluating the outcome of new surgical procedures.

0.05) in the two periods,the ratio of tracheostomy was significantly higher (P

Objective To summarize the experience and the outcome of the reconstructive operation with colon or stomach for scarred stricture after esophageal burns. Methods This retrospective report reviews the clinical history of reconstructive operation with colon or stomach for scarred stricture after esophageal burns. 74 cases underwent esophageal reconstruction by colon without resection of scarred esophagus, 26 cases esophagogastric reconstruction with resection of scarred esophagus. Results In the group reconstructed with colon there were 5 postoperative deaths, including mediastinal infection caused by necrosis of transposition colon in 2 cases. Other postoperative complications included cervical anastomotic leakage in 14 cases and anastomotic stenosis in 4 cases. In the group reconstructed with stomach, there was no operative death and only 2 anastomotic stenosis and one empyema occurred after operation. Conclusion The proximal esophageal scarred stricture beyond the lower edges of aortic arch could be replaced by colon bypass without resecting the scarred esophagus. The esophagogastrostomy could be performed after excising scarred esophagus with the anastomosis can be made below the aortic arch. The postoperative complications in the group of reconstruction with colon were higher than the group of reconstruction with stomach. Improvement in surgical technique may decrease the complication rate of reconstruction with colon.

Objective To evaluate the effects of TGF ? 1, EGF, bFGF, KGF on the cell growth of androgen independent prostate cancer cell line PC 3M in vitro. Methods We cultured androgen independent prostate cancer cell line PC 3M in vitro and added TGF ? 1, EGF, bFGF, KGF to the medium at different concentrations of 1, 5,10 and 50 ng/ml. Brdu incorporation method was used to determine the status of cell proliferation. Results The absorbance ( A ) value of the control group PC 3M was 0 759. Seventy two hours after adding the growth factors separately, the inhibition was enhanced with the increasing of concentrations. At the dosage of 50 ng/ml, A value decreased to 0 400(TGF ? 1),0 455(EGF),0 532(bFGF),and 0 491(KGF),respectively, showing significant difference compared to the controls. When the mixture of 1 ng/ml EGF with 0 5 ng/ml or 5 ng/ml TGF ? 1 was added into the medium, A values were 0 522 and 0 299, respectively. Conclusions All these four growth factors inhibited the proliferation of PC 3M cell line in a dose dependent manner. TGF ? 1 and EGF have no interaction to the cell proliferation.

Objective To study the clinical significance of cryoanalgesia of intercostals nerves for relieving the chest pain and the stress after thoracotomy. Methods 166 patients undergone post-lateral thoracotomy were enrolled for study, including 107 cases of cryoanalgesia of intercostals nerves as cryo-group and 59 cases of non-cryoanalgesia as control group. The patients who had exploratory thoracotomy were excluded. The visual analogue scales (VAS), dosage of dolantin as well as the plasma levels of cortisol and ?-endorphin, and the complications after operation between the two groups were compared and analyzed. Results After operation, the VAS of cryo-group was much lower than that of control group for 7 days, so did the dosage of dolantin during the first 3 days. The complications in the control group were much more than that in the cryo-group who had lower levels of cortisol and ?-endorphin in plasma. Conclusion Cryoanalgesia of intercostals nerves was proved to be a simple, inexpensive, safe form for relieving post-thoracotomy pain. It could not only dramatically relieve the pain and stress level, but also reduce the risk of complications especially in elderly patients.

Objective To evaluate the therapeutic effect of single-sided lung volume reduction surgery (LVRS) with different resection volumes on obstructive emphysema in rabbit. Methods Obstructive emphysema was reproduced in 50 New Zealand white rabbits with smog and elastase, and they were randomly divided in equal number into emphysema (A), small volume LVRS (B), moderate volume LVRS (C), large volume LVRS (D), and shame operation (E) groups. LVRS with different resection volumes was carried out groups B, C, and D. Pulmonary functions, artery blood gas analysis and pulmonary histology were determined 8 weeks later. Results Compared with those in group A, vital volume (V T), 0.3 second forced expiratory volume (FEV 0.3), FEV 0.3/FVC (forced expiratory capacity), PaO 2, density of alveolar septum (Ds) and number of alveolus (Na) were increased postoperatively, and PaCO 2, total lung capacity (TLC), functional residual capacity (FRC) and diameter of alveolus (Da) were decreased in group C (P0.01). Morphological improvements of emphysema were noticed under naked eye and optical microscope only in C group. Conclusion Single-sided LVRS with appropriate resection volume can improve effectively obstructive pulmonary emphysema in rabbit.

Objective To study the feasibility and efficacy of operative method of maximal thymectomy by video-assisted thoracoscopic surgery(VATS)for myasthenia gravis(MG).Methods From August 2005 to June 2007,27 patients with MG received maximal thymectomy by VATS(VATS group).The thymus and fat tissues in the anterior and upper mediastinum were resected.Patients who received transsternal thymectomy from May 2004 to July 2005 served as a control(conventional group).Results In the VATS group,the maximal thymectomy by VATS was completed in 26 patients,one patient was converted to open surgery because of the injury to the brachiocephalic vein.Compared with the conventional group,the patients in the VATS group had fewer blood loss [(46.0?5.7)ml vs(120.0?18.8)ml,t=-19.231,P=0.000],lower level of analgesic requirement(3 vs 12,?2=7.068,P=0.008),and shorter postoperative hospital stay [(7.0?1.2)d vs(11.0?2.5)d,t=-7.379,P=0.000].There was no significant difference in the operation time,myasthenia gravis crisis,and surgical outcomes between the two groups.Conclusions Maximal thymectomy by VATS is feasible and safe for patients with MG.Patients have shorter hospitalization,less surgical trauma and pain,lower rate of complication,and quicker recovery after the treatment.Further studies are needed to investigate its long-term efficacy

From May 1981 to September 1983. experimental study of the effect of buried nerve endings into muscles on the recovery of its motor functions was carried out in our hospital with 40 robust rabbits of both-sexes divided into two groups. In group A. left common peroneal nerve was cut off at the relatively deep site of myoneural junction and divided into three bundles, which were separately buried into long extensor muscle of digits, anterior tibial muscle and long peroneal muscle. For group B. a piece of 1.2cm cut from left common peroneal nerve and another piece of 1.4cm cut from right common per-oneal nerve were freely transplanted to the left-side muscles in the same way as in group A. Experimental results showed that the motor function of the muscles transplanted with nerve ending started to recover in two months after operation, and that the muscle power reached more than the 4th grading and electric irritation could induce muscle contraction at the 6th month after operation. Electromyogra-phic examination showed mixed disturbing potential. The new motor end-plates could be found on his-tological examination. In one clinical case follow-up for 6 months was made post-operatively and the recovering muscle power was fairly satisfactory.