Narcolepsy is a common chronic sleep disorder attacking adolescence,characterized by a typical tetrad of excessive daytime sleepiness,cataplexy,sleep paralysis and hypnagonic/hypnopompic hallucinations,affecting both mental and psychological aspects of children.Thus,making an early diagnosis and therapy is of great importance.Clinical diagnosis mainly depends on the multiple sleep latency test across the video electroencephalogram.In this article,we mainly describe the diagnosis and treatment progress of pediatric narcolepsy and clinical value of video-electroencephalogram.

Objective To investigate the relationship between PreS1 antigen and five items of HBV serological markers(HBV M), as well as the clinical significance of combined measurement of PreS1 antigen and HBV M in patients with hepatitis B. Methods Enzyme linked immunosorbent assay (ELISA) was applied to testing serum in 268 patients with hepatitis B. Results The detection rate of PreS1 antigen was 85.88% in HBeAg'positive samples,significantly higher than that in HBeAg nega-tive samples(39.34%), P<0.01. Conclusion PreS1 antigen may effectively reflect the situation of HBV amplification. Combined measurement of PreS1 antigen and HBV serological markers in clinical examination contributes to clinical diagnosis,therapeutic effect monitoring and prognosis evaluation.

The branches of the a. iliaca int. and ext. of 60 Chinese male adult cadavers (120sides) were studied and the findings are as follows: 1. The average length of the internal iliac trunk is 4.35?0.17cm,?=?1.34cm,in the left, and 4.56?0.21cm,?=?1.63 cm in the right. It is inversely proportionalto the average length of the common iliac artery. 2. The patterns of the branching of the superior, inferior gluteal and internalpudendal artieries may be classified into 5 types: type Ⅰ is present in 63 sides (cases)(52.5?4.55%); type Ⅱ and Ⅲ occur in 26 cases (21.67?3.76%); type Ⅳ occursin 4 cases (3.33?1.64%) and type Ⅴ is present only in 1 side (0.85 0.83%). 3. In most of the cases, the superior gluteal artery passes between the lumbosacraltrunk and the first sacral nerve (79.83%), while the inferior gluteal (66.67%) and theinternal pudendal artery (62.19%) usually pass between the second and third sacralnerve into the gluteal region. A few of these vessels may divide into 2 or 3 branchesbefore leaving the pelvis. 4. The accessory pudendal artery is present in 13 cases (10.83?2.83%). 5. The obturator artery originates from the internal iliac artery in 102 cases(85.0?3.26%), most of them spring from the anterior trunk of the internal iliacartery. In the other 18 cases, 2 spring directly from the external iliac artery (1.67?1.17%), 13 from the inferior epigastric artery (10.83?2.85%), and 3 have doubleorigins (2.5?1.42%), in which the 2 branches spring separately from the internal iliacand inferior epigastric artery. These abnormal obturator arteries occur in 14 cadavers(23.33?5.44%). 6. The iliolumbar artery is present in 80 cases (66.67?4.30%) as a singlebranch, in 37 cases (30.83?4.2%) with 2 separate branches and in 3 cases (2.5?1.43%) with 3 branches. It has various origins, most of them spring from the maintrunk or from the posterior trunk of the internal iliac artery. 7. The lateral sacral artery occurs in 54 cases (45.0?4.54%) as a single branch,in 57 cases (47.5?4.55%) with 2 branches, and in 9 cases (7.5?2.44%) with 3branches. Its origin is comparatively constant, usually arising from the posterior trunkof the internal iliac artery. 8. Most of the superior vesical arteries spring from the root of the umbilical artery.The number of branches of this vessel varies from 1 to 6, but most of them have 1 (46cases, 38.33?4.43%) or 2 (45 cases, 37.5?4.42%) branches. 9. The inferior vesical artery has 1--3 branches. Most of them have a singlebranch (104 cases, 86.67?3.1%), it springs commonly from the anterior trunk of theinternal iliac artery or from the internal pudendal artery. 10. The deferent artery springs in 85 cases (70.83?4.15%) as a single branch,and in 35 (29.17?4.15%) with 2 branches. In the single-branch type it springsmostly from the root of the umbilical artery, and in the two-branch type both springcommonly from the superior vesical artery. 11. The inferior rectal (middle hemorrhoidal) artery is present only in 106 cases(88.33?2.93%), most of them spring from the internal pudendal and inferior glutealarteries. In 3 cadavers (5.0?1.99%) they spring from the middle sacral artery sym-metrically. 12. In 103 cases (85.85?3.32%) the inferior epigastric artery springs indepen-dently from the external iliac artery, in 16 cases (13.33?3.13%) it springs as a com-mon trunk with the obturator artery, and in one side (0.83?0.83%) with the medialfemoral circumflex artery. Its origin-site on the external iliac artery is proxmal to theinguinal ligament in 69 cases (57.5?4.51%) with an average distance of 0.95?0.10cm,?=?0.59cm in the left, and 0.73?0.08 cm,?=?0.43 cm in the right; in 43cases (35.83?4.67%) the origin-site is just behind the ligament; and in 8 cases(6.67?2.28%) it is distal to the ligament, its average distance is 0.48?0.09 cm,?=?0.18 cm in the left, and 0.45?0.11 cm,?=?0.22 cm in the right. 13. The deep iliac circumflex artery, a single branch, is present in 115 cases(95.83?1.82%), the remaining 5 cases (4.17?1.82%) have 2 branches. In 54cases (45.0?4.54%) its origin-site is just behind the inguinal ligament; in 36 cases(30.0?4.18%) is proximal to the ligament with an average distance of 0.56?0.09cm,?=?0.38 cm in the left, and 0.61?0.09 cm,?=?0.35 cm in the right; and in25 cases (20.83?3.72%) it is distal to the ligament, the average distance shows0.62?0.12 cm,?=?0.45 cm in the left, and 0.69?0.12 cm,?=?0.41 cm in theright.

Objective To explore the Troponin I(cTnI) ,myoglobin(MYO) and creatine kinase isoenzyme(CK‐MB) in early di‐agnosis of acute myocardial infarction(AMI) ,and compare their significance in the diagnosis of AMI .Methods used chemilumines‐cence method in 126 patients with AMI and 82 cases of myocardial infarction group to test cTnI ,MYO and CK‐MB ,the results were compared .Results The cTnI ,MYO ,CK‐MB quality appear time and peak time was different ,in patients with acute myocardial in‐farction(cTnI ,MYO and CK‐MB joint detection sensitivity ,specificity ,negative predictive value ,positive predictive value was higher than single test .Conclusion cTnI ,MYO and CK‐MB joint detection is helpful to early diagnosis of AMI .

Objective To reveal the research focus of schistosomiasis in China through analyzing highly cited schistosomiasis related papers in journals from 2005 to 2012,so as to provide the information for formulating the plan of selecting topics of the edi-tors. Methods The published articles related to schistosomiasis in CNKI from 2005 to 2012 were collected,the citation frequen-cy of the papers was calculated according to formula,and the highly cited papers were selected according to the citation frequency. Then the information of highly cited papers including the published time,type,author and author affiliation,citation frequency, journal,grant and research item,research status and development tendency were analyzed. Results A total of 3 639 published papers related to schistosomiasis were searched and 343 papers(the citation frequency≥8)were selected as highly cited papers, and Chinese Journal of Schistosomiasis Control shared 45.19%of them. Among these papers,original articles,reviews and special reports occupied 44.90%,12.54%and 6.12%,respectively. The first authors of these papers were mainly from centers for disease control and prevention(CDCs)(17.33%),research institutions(22.67%)and colleges/universities(36.00%). Totally 50.44%of the articles received financial supports from research funds/foundations,and most of them were national or provincial funds. The research hotspots focused on epidemiology and prevention,epidemic situation analysis,vaccine,immunologic diagnosis,pharma-ceutical research,immunity and infection. Conclusions The highly cited papers related to schistosomiasis are mainly from CDCs,institutions and colleges/universities. The research hotspots mainly focus on epidemiology and prevention,vaccine,immu-nology and pharmaceutical study. The related journals can use this information to chose topic and solicit contributions to improve their influence.

Multilocus sequence typing MLST with high solution sensitivity and specificity is widely used to study the population genetic structure of pathogen by amplification and sequencing of the housekeeping genes. MLST also provides more evidence and plays an important role in parasite research. This paper reviews the principle and method of MLST and its applica-tion on population genetic structure analysis of parasites.

Objective To understand the the current situation of the slogans in the schistosomiasis health education from the linguistic aspect.Methods Sixty-two slogans in the schistosomiasis health education were collected,then the rationality and validity of them were analyzed from two aspects :the language form and the semantic content.Results Most of the slogans had the appropriate language form and the rational semantic content,they could propagandize the policy and educate the people very well,but there were still some slogans had the inappropriate language form or have the irrational semantic content and so on.Conclusion In order to make the slogans in the schistosomiasis health education more effective,we should attach importance to the language form and the semantic content of them.

OBJECTIVETo systematically evaluate the effectiveness of integrative medicine (IM) for preventing postoperative recurrence of primary hepatic carcinomas (PHC).

METHODSSuch databases as The Cochrane Library, PubMed, EMbase, China National Knowledge Infrastructure (CNKI), VIP Database, Wan-fang Database were retrieved to collect randomized controlled trials (RCTs) on preventing postoperative recurrence of PHC by IM. The retrieval period started from database establishment to June 2013. Literature screening, data extraction, and quality evaluation were performed by two reviewers strictly according to inclusion criteria. Meta-analysis was conducted using RevMan 5.2 Software.

RESULTSA total of 5 RCTs involving 367 patient cases were included. Results of Meta-analysis showed that the IM group was superior to the Western medicine (WM) group in the 1-, 2-, and 3-year recurrence rates (P < 0.05).

CONCLUSIONIn the prevention of postoperative recurrence of PHC, the effectiveness of IM was more significant, when compared with treatment of Western medicine.

Drugs, Chinese Herbal ; therapeutic use ; Humans ; Integrative Medicine ; Liver Neoplasms ; prevention & control ; Neoplasm Recurrence, Local ; prevention & control ; Postoperative Period ; Randomized Controlled Trials as Topic ; Treatment Outcome

Objective To analyze the discourse right construction of China’s medical aid to Africa,so as to provide evidenc?es for improving the effect and sustainable development of China’s medical aid to Africa. Methods The documents of the dis?course right that China constructed in the medical aid to Africa were selected at different periods as discourse samples. The achievement and deficiency were analyzed from four aspects,namely confident,charismatic,influential,and dominant. Re?sults China’s medical team made much in the discourse right construction in their aid to Africa,but some China’s medical team members were still too cautious and too low?key. China’s medical team gained the trust of the people of Africa,but the lan?guage communication difficulties still hampered in China’s medical aid to Africa. Chinese medical team were widely praised by the African society,but in the west,some African media,even China’s media still neglected to report China’s doctors. China’s international discourse right were greatly improved,but western countries still dominated the public opinion. Conclusion Chi?na should refer to the actual situation of medical aid to Africa to strengthen the construction of discourse right.

Objective To study the cytopathogenic effect of epidemic hemorrhagic fever with renal syndrome virus (HFRSV) on renal tubular cells(RTC). Methods Human fetal renal tubular cells (HFRTC) were cultured in vitro. HFRTC infected or not infected by HFRSV were observed by using trypan-blue stain and transmission electron microscopy(TEM). Viral-mRNA was detected by in situ molecular hybridization. Results (1) HFRSV could directly infected HFRTC: (2)The death rate of HFRTC in the infection group was significantly higher than that in the control grou 1 to 4 weeks after infection; (3) Injuries of cell membrane and cell organs after infection with HFRSV were significantly earlier and more severe as compared to control by means of TEM. Conclusion HFRSV can directly damage renal tubular cells (RTC ), which contributes to the pathogenesis of hemorrhagic fever with renal syndrome (HFRS).