As a series of and continuous publication,the papers published on Chinese Traditional and Herbal Drugs in 2010 were selectively and briefly highlighted to reflect the new progress on modern research of Chinese herbal medicines.Within 617 articles,chemical constituents (127),pharmaceutics and technology (149),pharmacological studies and clinical observation,and medicinal materials are still major categories.Some comments have also been personally provided.

Abstract: In order to investigate immune protection against swine-origin influenza virus (S-OIV) A H1N1, the helper-dependent adenovirus vector (HDAd) system was exploited to construct recombinant HDAd encoding hemagglutinin (HA). The HA gene was synthesized and cloned to the HDAd backbone. Then, the HDAd/HA DNA molecules were transfected into 293Cre4 cells with calcium phosphate. The cells were infected by helper virus 16 hours after the transfection. The 293Cre4 cells were coinfected with HDAd/HA and the helper virus for large-scale preparation of HDAd/HA. The HDAd/HA was obtained and purified twice with CsCI density ultracentrifugation and observed morphologically under transmission electron microscope, and the expression of HA protein was analyzed with RTPCR. Recombinant HDAd/HA expressing HA protein was successfully constructed which could pave the way for in vivo investigation on immunogenicity and efficacy against S-OIV A H1N1 infection.
Adenoviridae ; Cell Line ; Cloning, Molecular ; Genetic Vectors ; Helper Viruses ; Hemagglutinin Glycoproteins, Influenza Virus ; biosynthesis ; Humans ; Influenza A Virus, H1N1 Subtype

Objective To observe the effect of mindfulness-based cognitive therapy (MBCT) on dysphagia after stroke. Methods From October, 2017 to March, 2018, 60 stroke patients with dysphagia were randomly divided into control group (n = 30) and experimental group (n = 30). Both groups received routine swallowing training, while the experimental group received MBCT in addition, for eight weeks. They were investigated the compliance, and assessed with Kubota Drinking Water Test (KDWT) and Hospital Anxiety and Depression Scale (HADS) before and after intervention. Results The compliance improved in the experimental group after intervention (χ2 = 19.000, P < 0.001), and it was better in the experimental group than in the control group (χ2 = 8.044, P < 0.05). While the scores of KDWT improved in both groups (Z > 1.970, P < 0.05), and improved more in the experimental group than in the control group (Z = -2.093, P < 0.05); the scores of HADS improved in both groups (t > 9.510, P < 0.001), the total scores and the subscale scores of anxiety and depression improved more in the experimental group than in the control group (t > 2.133, P < 0.05). Conclusion MBCT could increase the compliance in swallowing training for stroke patients with dysphagia to improve their swallowing function, anxiety and depression .