2.Comparisons of clinical characteristics in patients with rosacea between Uygur and Han nationality in xinjiang
Yanyan FENG ; Junfeng YU ; Mengke LI
Journal of Chinese Physician 2016;18(2):175-177
Objective To explore the clinical characteristics of rosacea in Xinjiang.Methods From Jan 2013 to Jun 2015,clinical data of hospitalized patients who were diagnosed in the People's Hospital of Xinjiang Autonomous Region as rosacea were analyzed retrospectively.Results (1) The onset age of Uygur and Han were similar,while the incidence of Han was higher than Uygur in 41 ~ 50 age group.(2) The ratio of outdoors was higher in Uygur patients than Han patients.(3) Reactive erythema was the mainly feature in Han patients with obviously self-conscious symptoms including burning,drying,and tingling.The Uyghur patients were present with persistent erythema,papules and pustules;and had facial swelling and mild symptoms.(4) Positive rates of thyroid related antibodies and prolactin were higher in patients with rosacea.Conclusions The clinical features of rosacea are different between Uygur and Han nationalities in Xinjiang.
3.Comparison of students' learning curves between Macintosh laryngoscope and Airtraq laryngoscope in endotracheal intubation
Hong ZHAO ; Yi FENG ; Yanyan ZHOU
Chinese Journal of Medical Education Research 2012;11(10):1020-1023
Objective To compare medical students' learning curve between Macintosh laryngoscope and optical laryngoscope in endotracheal intubation and to decide which one is more suitable for novice personnel.Methods Totally 26 interns after being trained by experienced anesthesiologists were enrolled in this study.They performed intubation on 6 patients by using both Macintosh laryngoscope and optical laryngoscope ( each laryngoscope for 3 patients) under the supervision of experienced anesthesiologists.The sequence of laryngoscope was determined by computer-generated random number list.Results Totally 149 patients who were ready to receive surgery under general anesthesia were enrolled in this randomized crossover controlled study.Duration of intubation was significantly shorter in Airtraq group (78 -± 33 ) s than in Macintosh group (114 ± 32) s,P < 0.001.Intubation success rate was significantly higher in Airtraq group than in Macintosh group ( 87.8% vs.66.7%,P < 0.05 ).Conclusions With the advantages of rapid learning curve,higher intubation success rate and shorter intubation duration,Airtraq laryngoscope is easier to master for novice personnel.
4.The changes and clinical significance of heart-type fatty acid binding protein and soluble ST2 protein in children with chronic heart failu re
Yanyan MA ; Song FENG ; Binglu LI ; Jindou AN
Journal of Clinical Pediatrics 2015;(9):802-806
ObjectiveTo study the changes and clinical significance of serum heart-type fatty acid-binding protein (H-FABP) and soluble ST2 protein (sST2) in children with chronic heart failure (CHF).MethodsThirty-nine children with CHF and 30 healthy children were recruited. Serum levels of H-FABP and sST2 were determined by ELISA, The left ventricular ejection fraction (LVEF) and fractional shortening of the left ventricle (LVFS) were measured by two-dimensional echocardiog-raphy.ResultsIn 39 children with CHF, 15 males and 24 females, aged 2 months to 14 years, included 27 cases of endocardial ifbroelastosis (EFE) and 12 cases of dilated cardiomyopathy (DCM). According to the cardiac functional grading standard, the children with CHF were divided into 10 cases with cardiac function II, 15 cases with cardiac function III, and 14 cases with cardiac function IV. The mean levels of H-FABP, sST2 and NT-Pro-BNP in children with CHF at stage of heart failure and heart failure remission were statistically higher than those in the healthy children (allP<0.01). The serum H-FABP and sST2 levels had signiifcant differences among groups grouped according to cardiac functional grading standard (allP<0.05). The serum H-FABP and sST2 levels had no signiifcant difference between the EFE and DCM groups (allP>0.05). The Spearman correlation analysis showed that, in children with CHF at stage of heart failure, the serum H-FABP level was positively correlated with NT-Pro-BNP, sST2 and cardiac function (r=0.402、0.621、0.644,P<0.05). Serum sST2 level was positively correlated with NT-Pro-BNP and cardiac function (r = 0.501、0.678,P<0.05), and was negatively correlated with LVEF and LVFS (r=?0.340、?0.329, P<0.05).ConclusionsH-FABP and sST2 are involved in the development of heart failure. H-FABP and sST2 can be used as reference indices for clinical diagnosis and assessment of CHF.
5.Effect of Bushen Tiaojing Decoction on Serum Leptin, Insulin and Tes tosterone of Polycystic Ovary Syndrome Model Rats
Guangrong FENG ; Xiaohua HU ; Yanyan ZHOU
Journal of Traditional Chinese Medicine 1993;0(04):-
Objective To observe the effect and mechanism of Bush en Tiaojing Decoction (Decocti on for reinforcing the kidney and regulating the menstruation) on ovulation of p olycystic ovary syndrome (PCOS) rats. Methods Eighty fe male SD rats were made PCOS models and randomized into blank group, model group, metformin group, Bushen Tiaojing Decoction high and low dose group s, with 10 ones in each and the remainders removed. The changes of serum leptin, ins ulin and testosterone in each group were observed. Results In Bushen Tiaoji ng Decoction high and low dose groups, serum leptin, insulin and testosteron e were all decreased. The effect of Bushen Tiaojing Decoction high dose group wa s similar with that of metformin group in decreasing leptin, insulin a nd testosterone. Conclusion Bushen Tiaojing Decoction c ould improve the ovulation of PCOS rats through regulating leptin, insulin , and testosterone.
6.Practice and Thinking over Construction of Morning Meeting System in Clinical Departments
Yanyan CHEN ; Zhibin CHEN ; Huayue FENG
Modern Hospital 2016;16(1):95-96,97
Morning meeting is regular in clinical departments.Through enriching meeting contents, exten-ding meeting function, morning meeting becomes an effective internal management tool and platform in clinical depart-ments, and plays a positive role in the culture construction of the department, quality management, personnel train-ing, etc.
7.Clinical Study of Jitongning Capsule in the Treatment of Ankylosing Spondylitis
Yanyan WANG ; Feng HUANG ; Aizhen HAO
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(04):-
Objective To evaluate in a large open study if Jitongning capsule is potentially useful in the treatment of ankylosing spondylitis, and observe the safety of Jitongning capsule. Methods Sixty-five patients with ankylosing spondylitis were recruited. Jitongning capsule group were thirty-five patients, using Jitongning capsule at a dose of 4.2 g/d. The control group was using Sulfasalazine. There were thirty patients, using Sulfasalazine at a dose of 2.0 g/d. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), the Bath Ankylosing Spondylitis Metrology Index (BASMI), patient’s global assessment, total body pain, spinal pain and night pain, ESR and CRP were measured at 1, 3, 6 months. The primary end point in this study was the proportion of patients with a 20% improvement response according to the ASAS International Working Group criteria (ASAS20 responders) at month 1, 3, 6. Results The study was completed on 56 patients. The treatment group was completed on 33 patients. The control group was completed on 23 patients. Side effects of two groups were uncommon and well tolerated. The ASAS20 was achieved by 66.67% of patients in the treatment group and by 60.86% of patients in the control group at month 6. Conclusion Jitongning capsule can treat the patients of earlier and mid-half ankylosing spondylitis. That is safety and similar to Sulfasalazine.
8.Experimental Study on Anti-inflammatory and Analgesic Effects of Jitongning Capsule
Yanyan WANG ; Zheng ZHAO ; Feng HUANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(09):-
Objective To study the anti-inflammatory and analgesic effects of Jingtongning Capsule. Methods Models of acute inflammatory reactions of croton oil-induced mouse ear edema and carrageenan-induced rat raw swelling and chronic inflammatory reaction of cotton ball-induced mouse granuloma in abdominal cavity were performed to study the anti-inflammatory effects of Jingtongning Capsule. Model of acetic acid-induced writhing in mice was used to study the analgesic effect of Jingtongning Capsule. Results Jingtongning Capsule significantly suppressed croton oil-induced mouse ear edema and carrageenan-induce rat paw swelling. Cotton ball-induced mouse granuloma in abdominal cavity was also markedly reduced by Jingtongning Capsule. The writhing times of mice induced by acetic acid were decreased by Jingtongning Capsule. Conclusions Jingtongning Capsule has obvious anti-inflammatory effect on acute and chronic inflammatory reactions. The pain reactions induced by chemical stimulus was significantly relieved by Jingtongning Capsule.
9.An analysis of abnormal magnetic resonance imaging of sacroiliac joints in patients misdiagnosed as spondyloarthritis
Zheng ZHAO ; Yanyan WANG ; Jingyu JIN ; Xiaohu DENG ; Feng HUANG
Chinese Journal of Internal Medicine 2014;53(9):724-729
Objective To study the imaging features of sacroiliac joints(SIJ) in patients who were misdiagnosed as spondyloarthritis(SpA).Methods A total of 34 patients with chief complaint of back pain and misdiagnosed as SpA from January 2007 to April 2013 in Department of Rheumatology Chinese PLA General Hospital were enrolled.The imaging,clinical manifestations,laboratory examinations data were analyzed.Result The main reason for misdiagnosis as SpA was because of sacroiliitis presenting on imaging.The final diagnoses included 24 patients as SIJ infection,4 patients as neoplastic diseases,2 patients as metabolic bone diseases,2 patients as sacroiliac joint degeneration,1 patient as gout of sacroiliac joint,1 patient as diffuse idiopathic bone hypertrophy.For patients with infection,there were 10 patients receiving X-ray and 22 patients receiving CT of SIJ.However,5 and 7 patients had negative results respectively.These patients with infection had abnormalities in MRI including all with bone marrow edema,21 patients with erosion of bone and joint,22 patients with muscle involved.As to the patients with malignancies,SIJ CT scan appeared normal.Bone marrow edema and erosion in MRI were found in all neoplasm patients expect one as ependymoma.Adjacent muscles were involved in the patient with Ewing's sarcoma.Either X-ray or CT in other patients demonstrated obvious abnormalities,but only mild erosion of bone was found in MRI.Conclusion Bone marrow edema of SIJ in MRI represented not only in patients with SpA.Rheumatologists should analyze the clinical manifestations and laboratory examinations comprehensively in order to avoid the misdiagnoses.
10.Research progress of H type hypertension
Yanyan BAI ; Liuliu FENG ; Hongman HUANG ; Xinbing LIU ; Qidan XU
Chinese Journal of cardiovascular Rehabilitation Medicine 2014;23(5):589-591
H type hypertension is essential hypertension complicated elevated plasma homocysteine level ,which ac-counts for about 75% in Chinese adults with hypertension and is closely related to cerebral stroke and other cardio-vascular diseases .Lowering homocysteine level in patients with hypertension possesses important significance for preventing stroke .