1.Design Concept and Method of Case Report Forms in Optimum Research on Famous TCM ;Doctors’ Experienced Prescriptions
Lili XU ; Runshun ZHANG ; Yinghui WANG ; Baoyan LIU ; Yanxing XUE ; Guanli SONG
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(9):15-17,18
Optimum research on famous TCM doctors’ experienced prescriptions can optimize the composition of prescriptions which originated from experienced prescriptions, clarify the functions of indications and efficacy features of experienced prescriptions. Case report forms which are normally adapted to clinical new medicine study cannot meet the demand of observational study to optimize experienced prescriptions. This article expounded design features, structure elements and collection timing and proposed requirements for information collection through practice of case report forms in the optimum research on famous TCM doctors’ experienced prescriptions, with a purpose to realize the optimization of experienced prescriptions through observational study on famous TCM doctors’ experienced prescriptions and provide evidence for further clinical research on experienced prescriptions.
2.A Research on the Discovery Methods in Prescription and Medication Based on Professor Xue Boshou's Clinical Prescription Data
Weilian KONG ; Lili XU ; Yanxing XUE ; Baoyan LIU ; Yinghui WANG ; Xuezhong ZHOU ; Runshun ZHANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(1):55-62
How to discover the valuable knowledge from the large amount of prescription data accumulated in the long-term medical practice of traditional Chinese medicine (TCM) is one of the important contents of TCM modernization.Based on the prescription data of Xue' s clinical practice of many years,this paper explored the method of combining TCM network and prescription network to find out Xue' s common core drug combination.Based on 9,584 prescriptions in the Hospital Information System of Guang'anmen Hospital of China Academy of Chinese Medical Sciences,prescription network and drug network were constructed according to the similarity of prescription composition and drug co-occurrence relationship.Using the complex network analysis methods,such as community analysis method,to analyze the prescription and drug compatibility,the results were evaluated and analyzed by Xue and his successors.As a result,through complex network analysis,126 modular prescriptions and 4 TCM modules were obtained.One of the core components of the prescription module included Xiao Chai Hu decoction,Yin Qiao powder,and Sheng Jiang powder compound addition and subtraction.It was in consistent with the drug composition of exogenous febrile prescriptions excavated earlier.In conclusion,using the complex network methods,we can get some core drug combinations prescribed by Prof.Xue,and achieve the common compound core drug combination for treating diseases with certain vantages,laying a foundation for further inheriting and excavating Xue' s effective experience.
3.Insights into Treatment of Modern Epidemic Diseases from Xiangsu Powder (香苏散) inTreatment of Cold Epidemics
Shizhe SHAN ; Bo WEN ; Wenbo SHAO ; Yanxing XUE
Journal of Traditional Chinese Medicine 2024;65(9):966-969
The prescription of Xiangsu Powder (香苏散) reflects the exquisite balance in treating both the superficial and deep layers, harmonizing the body's vital energy and blood, and addressing the functions of the triple energizer simultaneously. Its application in treating cold epidemics has been a long time, yet its importance in modern disease treatment is often overlooked. Based on the treatment principles demonstrated by Xiangsu Powder in treating cold epidemics, it is proposed that in the treatment of modern epidemic diseases, the dual principles of cold and heat should not be neglected. When cold pathogens stagnate at the surface, they should be dispersed and detoxified, using methods that induce sweating to expel them from the surface. When cold and dampness coexist, efforts should be made to regulate the flow of vital energy, blood, and body fluids to restore the proper functioning of the three burners. When cold-induced pathogenic factors are severe and toxic, aromatic herbs should be utilized to dispel turbidity and avoid contamination. Throughout the entire course of treating epidemic diseases, attention should be paid to inducing sweating without damaging the body's vital energy, while also protecting the body's righteous qi, with the aim of providing refe-rence for the treatment of modern epidemic diseases.
4.Experience of XUE Boshou in Using Fangfeng (Radix Saposhnikoviae) in Clinical Practice
Shizhe SHAN ; Haiyu ZHANG ; Wenbo SHAO ; Yanxing XUE
Journal of Traditional Chinese Medicine 2024;65(16):1646-1649
This paper summarized professor XUE Boshou's clinical experience of using Fangfeng (Radix Saposhnikoviae). Firstly, Fangfeng is used to scatter wind and release the exterior, disseminate and penetrate the pathogens, and can treat the early-staged externally contracted heat diseases with exterior qi constraint and blocking, and serious internal heat through Xiaodu Xijiao Beverage (消毒犀角饮) from Beneficial Formulas from the Taiping Imperial Pharmacy (《太平惠民和剂局方》)combined with Yinqiao Powder (银翘散), Shengjiang Powder (升降散) and Zhizichi Decoction (栀子豉汤) in their modifications. Secondly, it eliminates wind and dispels dampness, relieves itching, and heals sores, with self-made Xue's Guomin Decoction (薛氏过敏煎) in modification being formulated to treat allergic skin diseases caused by pathogenic wind attacking the exterior. Thirdly, it disperses liver qi and soothes the spleen, lifts yang and stops diarrhea, and can be used in modified Tong Xie Yao Formula (痛泻要方) from Teachings of ZHU Danxi (《丹溪心法》) when treating diarrhea caused by liver constraint and spleen deficiency. Fourthly, it can disperse stagnated qi throughout the body and unblock the meridians of the five zang (脏) organs, commonly in formulation of modified Huangqi Chifeng Decoction (黄芪赤风汤) from Correction of Errors in Medical Works (《医林改错》) to treat patients with qi deficiency and blood stasis after radiotherapy and chemotherapy of tumors, as well as alopecia areata or even alopecia universalis, chronic rhinitis and others.