The demand is higher to medicine education in the condition of constructing harmonious society.Human culture is the certain value request.This paper has discussed the inevitability that modem medicine turns to human culture harmonious society. There are three aspects mentioned to implement the human culture aim.Namely,blending human culture spirit in the specialty education,raising human culture spirit in traditional culture and constructing harmonious campus culture.

Since medicine possesses the nature of humanity,life education has remarkable significance for medical students.By interpreting teaching experience in the curriculum of interpretation of life and death,this paper explores the importance of life education in cultivating overall quality of medical graduates.Education should not only answer the questions in life,but also guide us go through the significance of life,and surpass the wonders of life.As for medical students,the curriculum of life and death is also a crucial approach to enhancing educational effect and cultivating their quality of humanistic care,thus much emphasis should be paid to the curriculum of interpretation of life and death.

Medical humanistic education becomes “remarkable leaning” because many problems arise from the development of contemporary medicine such as the meaning of life,the medical aim,the medical model and doctor-patient relationship etc.Multi-channel and multi-modal development of medical humanistic education has become a must to understand medicine and makes it develope soundly,and all-directional resultant force and the environment of medical humanistic education,striving for studies,is an exploration and even a mission and responsibility

Pancreatic cystic lesions (PCLs)have various pathological types,extremely different biological behaviors,and different progno-sis.Current diagnosis of PCLs mainly depends on a comprehensive analysis of the patient's medical history,clinical manifestations,imaging examinations,serological examinations,fine needle aspiration biopsy,and cytological examination of cyst fluid.Needle -based confocal la-ser endomicroscopy (nCLE)is a novel method of microscopic endoscopy and is compatible with 19 -gauge puncture needle.Under the guid-ance of endoscopic ultrasound,nCLE can achieve real -time in vivo imaging of the cellular and subcellular structures of diseased tissues and thus helps with the accurate diagnosis of PCLs.This article reviews the application of nCLE in the diagnosis of PCLs.

The development of social medicalization is mainly based on technical and capital logic.De-humanization of technology and the profits-pursing nature of capital cause unbalanced development of modern medicine in the aspects of materials and human as value subject.As a component of medical humanities education,life education should be based on human's emotion of life,strengthened in the cultivation of sympathy,respect as well as concern and control of subject's expansion by emotional strength,which is also an important element in the cultivation of medical humanities spirit.

As a core element of the Confucianism,mind-nature theory is full of the essence of Confucian mor-al education and has a profound influence on the Chinese national morality education.Confucianism mind-nature theory which takes Confucius and Mencius as representatives,after the continuous development of the future genera-tions,has been formed a complete ideological system.Confucianism mind-nature theory highly affirms the values of moral and unifies the values of life and moral.This article,by exploring the moral resources of Confucianism mind-nature theory,rethinks the ideas of contemporary ethics education and expounds how to enhance the effect of medical ethics education.

Abstracts Experience in total parenteral nutrition (TPN) support for 27 patients with acute severe panereatitis is presented. Most patients were seriously ill, and the course were long and complicated with a mean duration of 64 days, and the longest one was 179 days. Metabolic disturbance and malnutrition were very conspicuous. The mean duration of TPN support for each patient was 24 days, and the longest one maintained for 72 days. TPN began from the early stage and cover the whole period of alimentary dysfunction until the patient could take food by mouth in most patients. Combined treatment was important, ineluding: early operation in 19 patients, intra-and/or postoperative lavage of pancreatic bed and and peritoneal cavity in 13 patients, and as well as appropriated conservative management. Late operative drainage for pancreatic abscess was done in 7 cases. Results Were satisfactory with 22 (81. 5% ) were cured and 5 (18. 5% ) died. In the latter, 3 were died of pancreatic sepsis complicated with infective shock, 2 died of exhaustion, together with pneumonia and multiple system organ filure. None of early died.

Objective To evaluate the role of angiotensin Ⅱ receptors in the development of neuropathic pain (NP) in rats.Methods Seventy-five male Sprague-Dawley rats,weighing 230-270 g,were randomly divided into 5 groups (n =15 each) using a random number table:sham operation group (group S),group NP,telmisartan (angiotensin Ⅱ receptor antagonist) 2 mg group (group T1),telmisartan 5 mg group (group T2),and telmisartan 10 mg group (group T3).NP was induced by chronic constrictive injury (CCI) in chloral hydrateanesthetized rats.The sciatic nerve was exposed and 4 loose ligatures were placed on the sciatic nerve at 1 mm intervals with 4-0 silk thread.In S group,the sciatic nerves were exposed but not ligated.Telmisartan 2,5 and 10 mg/kg were perfused via stomach once a day for 14 consecutive days in T1,T2 and T3 groups,respectively,while the equal volume of normal saline was given instead of telmisartan in S and NP groups.Mechanical and thermal pain thresholds were measured at 1 day before CCI and 3,7 and 14 days after CCI in each group.Results The mechanical and thermal pain thresholds were significantly decreased after CCI in NP,T1,T2 and T3 groups as compared with group S.The mechanical and thermal pain thresholds were significantly increased after CCI in T1,T2 and T3 groups as compared with group NP.The mechanical and thermal pain thresholds were significantly higher after CCI in T2 and T3 groups than in group T1.There was no significant difference in the mechanical and thermal pain thresholds between T2 and T3 groups.Conclusion Angiotensin Ⅱ receptors are involved in the development of NP in rats.

Objective To evaluate the effects of sevoflurane preconditioning on caveolin-3 expression during myocardial ischemia-reperfusion (I/R) in rats.Methods Healthy male Wistar rats,aged 6-8 weeks,weighing 250-300 g,were anesthetized with intraperitoneal pentobarbital 30 mg/kg and heparin 1 000 IU/kg.Their hearts were excised and perfused with K-H solution in a Langendorff apparatus.Thirty isolated rat hearts were randomly assigned into 3 groups (n =10 each) using a random number table:control group (group C),I/R group and sevoflurane preconditioning group (group SP).After 30 min of equilibration,group C was continuously perfused with K-H solution for 90 min,group I/R underwent 30 min of ischemia followed by 60 min of reperfusion,and group SP was perfused with K-H solution saturated with 2％ sevoflurane for 10 min followed by 5 min washout with K-H solution,then underwent 30 min of ischemia followed by 60 min of reperfusion.HR,left ventricular enddiastolic pressure (LVEDP),+ dp/dtmax and-dp/dtmax were recorded at the end of equilibration,immediately before ischemia and at 30 and 60 min of reperfusion.Myocardial specimens were obtained from the cardiac apex for microscopic examination.Myocardial specimens were obtained from the left ventricle for determination of caveolin3 expression.Results Compared with group C,+ dp/dtmax and-dp/dtmax were significantly decreased immediately before ischemia,and HR,LVDEP,+ dp/dtmax and-dp/dtmax were decreased at 30 and 60 min of reperfusion in groups I/R and SP,and caveolin-3 expression was down-regulated in group I/R and up-regulated in group SP (P ＜ 0.05).Compared with group I/R,HR,LVDEP,+ dp/dtmax and-dp/dtmax were significantly decreased immediately before ischemia and increased at 30 and 60 min of reperfusion,and caveolin-3 expression was up-regulated in group SP (P ＜ 0.05).The pathological changes were significantly attenuated in group SP as compared with group I/R.Conclusion The mechanism by which sevoflurane preconditioning attenuates myocardial I/R injury in rats may be related to up-regulation of myocardial caveolin-3 expression.

Low-triiodothyronine syndrome is a condition characterized by decreased total serum T 3 and free T3 , along with in-creased serum reverse triiodothyronine but normal levels of thyroxine and thyrotropin .However , it is not caused by the thyroid gland diseases.The latest research progress of mechanisms , diagnosis and clinical significance , and therapy strategy of low T 3 syndrome is reviewed in this paper .