Objective: To prepare modern tradional Chinese patent medicine Lemai capsules with a low dosage. Methods: Comparing the applications of seven kinds of macroporous adsorption resin in refinement of Lemai capsules' extracts in danshensu and paeoriflorin determined by HPLC as markers. Results: After refinement, the solid content of extracts decreased greatly. The content of danshensu became much lower than that before refinement The retention rate of AB 8、 X 5 and WLD for paeoriflorin is up to 80%. Conclusion: 7 kinds of macroporous adsorption resin are not proper to danshensu but some of them can be used to paeoriflorin.

Objective To study the clinical effect of ceramic cover anterior on teeth beauty.Methods 138 teeth in 34 patients with dental fluorosis were divided into two groups,the control group (69 teeth in 16 patients) was given traditional PFM cover repair,the treatment group (69 teeth in 18 patients) was given ceramic cover,they were followed up for three years.The teeth remaining rate and patient satisfaction were compared,the match color,edge fit,healthy gums,restoration integrity were compared according to the Ryge standard.Results Teeth remaining rate in treatment group was 95.7％,which was significantly higher than control group (P ＜ 0.05).The patient satisfaction was 94.4％ in treatment group and 87.5％ in the control group,the difference was significant (P ＜ 0.05).The match color,edge coloring,healthy gums and teeth sensitivity were not different between the two groups (P ＞ 0.05).The restoration integrity and marginal fit of treatment group was better than control group (P ＜ 0.05).Conclusion The clinical effect of ceramic faced in the anterior teeth beauty repair,especially in the repair of dental fluorosis is remarkable,and the remaining teeth rate higher,repair,dental restoration integrity and marginal fit is significantly better than that of resin repair,patient satisfaction is higher,the water area from non-beryl popularization and application.

Acute abdominal pain is a major clinical symptom of acute abdomen,and vasogenic acute abdomen caused by vascular diseases is rare and difficult to diagnose at its early stage with atypical clinical symptom and high mortality.Therefore,there is an urgent need to strengthen and improve the knowledge of surgeons about vasogenic acute abdomen.

TCM is unique and e ective on senile dementia in both theory and practice;therefore it is signi cant to generalize TCM understanding and experience on senile dementia for speci c therapy to reduce patients' cognition impairment and enhance their living quality.Sorting of TCM understanding on senile dementia pathogenesis and causes,it was clear that seniledementia was often seen in aging people characterized by de ciency in origin and excess in super ciality.Its de ciency in origin was de ciency of kidney essence,marrow and lucid yang failing to ascend.The origin aspect of senile dementia was believed to be the insu ciency of kidney.The de ciency of ve zang-organs was closely related to it.While the super ciality aspect was thought to be turbid phlegm and stagnant blood blocking brain and cerebral meridian with ve zang-organs all concerned.On one hand,the de ciency of kidney assisted by the de ciency of ve zang-organs could result in phlegm and blood stasis,that is to say excess resulted from de ciency.On the other hand,the stagnation of phlegm and blood stasis could block the generation,transformation and transportation of qi,blood and body uid,which would further consume the essence of the body.This is so-called de ciency transformed from excess.The above two aspects a ected each other and causing lingering pathogenic factors.

AIM: To improve the quantitive method of sarsasapogin in Kangbindu Tablet(Rhizoma Anemarrhenae, Fructus Forsythiae, etc.) METHODS: Applying HPLC-ELSD to replace TLCS. RESULTS: The new method was better than the old one in precise and repeat. CONCLUSION: The new method HPLC-ELSD is more useful.

Members of the tripartite-motif (TRIM) protein family share a highly conserved domain architecture known as RBCC motif,which is composed of a RING finger domain,one or two B-box domains,a coiled-coil domain as well as diverse types of C-terminal regions.TRIM proteins can not only maintain the normal physiological functions of the body,but also regulate the development of various diseases.In the current review,we focus on recent advances in the structures of TRIM proteins and their functions in the development of viral infection,cancer and neurodegenerative disease.

Objective To explore the normal reference values of infant intelligence in Fagan test of infant Method Fagan test was carried out in 315 healthy infants aged 6.5～14.0 month in Shenyang,Tieling and Jinzhou in Liaoning province.Results Infants with cognitive exponent X≥54.6 might be considered to be normal in development,49.9

OBJECTIVE:To study the effect of Runchangtongbian mixture (an agent of loosing bowel to relive constipation) on bowel propulsion in mice. METHODS:The coom propulsion percentages in bowel in Runchangtongbian mixture group, model group (treated with bowel propulsion suppressants) and blank group were computed and compared, and the data were analyzed statistically. RESULTS:As compared with the blank group, bowel propulsion was greatly enhanced in Runchangtongbian mixture group(P

In recent years,great progress has been made in the theory and technology of proteomics.As embranchment of proteomics,serum proteomics has been payed more and more attention also.The advanced techniques have been applied in serum proteomics research,which promote the development of the methodology.A great advance has been made in serum proteomics research for seeking associated tumor markers,pharmacy and some non-cancer diseases.

Objective To compare the efficacy of anesthesia with dexmedetomidinc and midazolam combined with sufentanil in patients undergoing microwave coagulation therapy for liver cancer. Methods Forty ASA Ⅱ male patients, aged 35-62 yr, weighing 45-70 kg, scheduled for percutaneous microwave coagulation therapy,were randomly divided into 2 groups ( n = 20 each): midasolam group ( group Ⅰ ) and dexmedetomidine group ( group Ⅱ ). A loading dose of midazolam 40 μg/kg ( in normal saline 20 ml) was given intravenously over 10 min,followed by midasolam infusion at 40 μg·kg-1 ·h-1 in group Ⅰ . A loading dose of dexmedetomidine 1 μg/kg (in normal saline 20 ml ) was given intravenously over 10 min, followed by dexmedetomidine infusion at 0.5 loading dose of sufentanil 0.2 μg/kg was given, and then patient-controlled intravenous anesthesia with sufentsnil (background infusion 0.1 μg·kg-1 ·h-1 , bolus dose 0.1 μg/kg, lockout interval 3 min) was used. The operation was started 2 min after administration of the loading dose of sufentanil. Bradycardia, tachycardia, hypotension, hypertensinn and respiratory depression were recorded. The number of attempts and successfully delivered doses was also recorded. Results There was no significant difference in the incidence of bradycardia, tachycardia, hypotension and hypertension between the two groups ( P ＞ 0 .05). The incidence of respiratory depression was significantly lower, and the number of attempts and successfully delivered doses was smaller in group Ⅱ than in group Ⅰ ( P ＜ 0.05). Conclusion The efficacy of anesthesia with dexmedetomidine and sufentanil is better than that of anesthesia with midazolam and sufentanil in patients undergoing microwave coagulation therapy for liver cancer.