Objective To analyze the cost-effectiveness of the treatment of type 2 diabetes by 3 different drugs.Methods Through the retrospective analysis of 198 cases with T2DM and drug economics,to analyze the costeffectiveness of the Yamo Li(glimepiride),repaglinide(repaglinide) and Avandia(rosiglitazone).Results No significant difference was observed in the total effective rate among the 3 drugs.The cost-effectiveness ratios in Group A,B and C were 2.99,1.43 and 5.76.The cost-effectiveness ratios increments in Group A,B and C were 42.15,18.32 and 214.74.Conclusion Based on individual differences of the patients,doctor should choose the drug with best treatment,lowest price and highest safety.

Objective To study the cognitive behaviors of ICU nurses about cluster intervention strategies of central venous catheter blood infection.Methods Two hundred and two ICU nurses were involved in the survey using self-designed questionnaire.Results The scores on knowledge of ICU nurses with cluster intervention strategies was(31.9±2.8)and the score on the cognitive behaviors was(26.9±2.6). Conclusions The ICU nurses’knowledge on cluster intervention strategies is at a general level and their behaviors are at the status ofseldomorsometimes.Therefore,improvement of manipulation flowsheet,control of routes for bacterial infections and enhancement of knowledge learning are critical for the improvement of cognitive behaviors of ICU nurses with cluster intervention strategies.

Objective:To establish the methods for the qualitative identification and content determination of aurantio-obtusin and chrysophanol in Zeju Jiangzhi tablets. Methods:A TLC method was adopted for the qualitative identification, and an HPLC method was used for the content determination. The determination was performed on a Wondasil C18 (250 mm × 4. 6 mm, 5 μm ) column with the mobile phase of acetonitrile -0. 1% phosphonic acid with gradient elution at the flow rate of 1. 0 ml?min-1 , the detection wave-length was 286 nm, the column temperature was 30℃ and the injection volume was 10μl. Results:The TLC spots of aurantio-obtusin and chrysophanol were clear and well-separated without any negative interference. The HPLC experiment results showed the good line-arity within the range of 1. 03-25. 72μg?ml-1(r=0. 999 9) for aurantio-obtusin, and 0. 48-11. 92μg?ml-1(r=0. 999 9) for chry-sophanol. The average recovery was 99. 21% and 98. 85%, and RSD was 0. 70% and 0. 73%, respectively (n=9). Conclusion:The method is simple, accurate and repeatable, which can be used for the qualitative identification and content determination of auran-tio-obtusin and chrysophanol in Zeju Jiangzhi tablets.

Objective To explore the baseline echocardiographic characteristics and the time course and recovery of left ventricular systolic function in patients with tachycardia-induced cardiomyopathy. Methods Fif-teen patients received radiofrequency cather ablation for tachycardiarrhymias from November 2012 to April 2017 were screened in this study.All 15 patients were examined by intracardiac electrophysiology and treated by RFCA under the guidance of three dimensional mapping system.All Patients received transthoracic echocardiography for 3-month follow-up.Levels of NT-proBNP before and after the ablation were compared. Results Successful abla-tion was performed in 14 of 15 patients. There was significant improvement in left ventricular ejection fraction (35.33 ± 6.11 vs. 57.93 ± 9.38%;P < 0.001). The LVEDD after treatment had significant differences(55.47 ± 8.06 vs.49.87 ± 8.99 P<0.001)after 3-month follow-up;the LAD after treatment decreased significantly(38.87 ± 3.27 mm vs. 35.20 ± 2.46;P < 0.001)and the levels of NT-proBNP decreased after ablation from 3 474.07 ± 3 400.59 pg/mL to 497.33 ± 437.84 pg/mL(P = 0.005). Conclusions Restoration of left ventricular systolic func-tion and reversal of LV remodeling can be achieved with successful elimination of tachycardia in the majority of pa-tients.NT-proBNP level elevates in subjects with TCM and decreases sharply after ablation.

Objective: To understand the needs of primary and secondary school students, parents and teachers for comprehensive sexuality education content, and to explore the applicability of comprehensive sexuality education content in China. Methods: By using the method of stratified cluster sampling, 5 571 primary and middle school students and 4 835 parents from Beijing, Chongqing, Heilongjiang (Harbin and Jiamusi) and Hubei (Wuhan and Xiaogan) were selected for questionnaire survey. Depending on the physical health monitoring points of various provinces and cities, 176 sexuality education related teachers in nine regions were surveyed. The development of the questionnaire was based on the content framework of comprehensive sexuality education proposed in the International Technical Guidelines for Sexuality Education. Results: Students had a higher demand for knowledge on the concepts of "relationship" (53.4% for primary school students, 57.6% for junior high school students) and "health and well-being skills" (71.1% for primary school students, 55.9% for junior high school students). Parents had higher demand for most comprehensive sexuality education content with the exception of lower need for "sex and sexual behavior (74.7% of primary school parents, 80.8% of junior high school parents)" and "sexual and reproductive health (primary parents 74.3%, junior high school parents 75.8%)". Teachers had a high demand for most comprehensive sexuality education content, but primary school teachers had a lower need for "values, rights, culture and sex(65.9%)", "sex and sexuality(60.1%)" and "sexual and reproductive health(66.8%)". The results of correspondence analysis showed that junior middle school teachers had the highest demand for comprehensive education content, followed by primary school parents, junior middle school parents, primary school teachers, junior middle school students and primary school students. Conclusion Teachers and parents have a higher demand for most comprehensive sexuality education content, while lower demand for some relatively sensitive content. Students have a relatively low demand for comprehensive sexuality education content. It is recommended to further improve the content of school sexuality education based on the actual needs of China.

Objective: To understand the awareness of sexual knowledge among primary and secondary school students, as well as their attitudes towards school sex education and to provide a reference for school-based sex education. Methods: A total of 5 531 primary and secondary school students were selected from Beijing, Chongqing, Heilongjiang (Harbin and Jiamusi) and Hubei (Wuhan and Xiaogan) by stratified cluster sampling and were investigated with self-reported questionnaire. Results: Sex-related knowledge scored 62.33±19.35, with a pass rate of 61.9%, and the excellent rate 17.5%. Sexual knowledge of junior high school students scored 64.30±19.07, with the pass rate of 64.7%, and the excellent rate 22.0%. A large proportion of primary students reported unaware of pubertal growth and HIV/AIDS-related knowledge, and a large proportion of junior high students unaware of reproductive physiology. Multivariate Logistic regression analysis showed region, grade, gender, and suburban areas were related to the level of sexual knowledge(P<0.05). More than 76.0% primary students and 85.9% middle school students agreed on the importance of school sexuality education. 59.7% of primary school students and 73.3% of junior high school students hoped to include school sexuality education in compulsory education courses; 59.8% of primary school students and 68.3% of junior high school students felt that school sexuality education should be equipped with specialized teachers. Conclusion Chinese primary and secondary school students are lack of sexual knowledge. As students have strong wills to get more information on sexual knowledge, schools should provide them with more comprehensive and effective sex education through appropriate courses and activities.