1.Pulmonary vascular development,diagnosis and treatment for pulmonary hypertension in preterm in-fants with bronchopulmonary dysplasia
Chinese Pediatric Emergency Medicine 2016;23(12):811-814
It is well known that pulmonary hypertension(PH) is one severe complication of bron-chopulmonary dysplasia( BPD) that is associated with high mortality. Aberrant pulmonary vascular growth, abnormal vasoreactivity and pulmonary vascular remodeling may ultimately lead to PH. Symptoms of PH of-ten overlap those of BPD itself. Furthermore,the emergence of symptoms may indicate that the disease has already progressed to a late, less reversible phase, thereby supporting arguments for screening all infants at risk. Echocardiography is non-invasive and widely available,and is currently the most commonly used screen-ing modality for PH in infants with BPD. Because the incidence of associated cardiovascular anomalies is high,cardiac catheterization and CT scanning of the chest should be considered in all infants who have signifi-cant PH despite optimal management of their lung disease. Early diagnosis and aggressive specific drug thera-py can improve the outcome for these patients.
2.The mechanism of hypoxia-induced persistent pulmonary hypertension of newborn and pulmonary vascular remodeling
International Journal of Pediatrics 2010;37(2):109-111,148
Persistent pulmonary hypertension of newborn (PPHN) is a clinical syndrome,characterized by pulmonary arterial pressure elevated relative to systemic blood pressure,leading to extrapulmonary right-to-left shunting of blood across the ductus arteriosus and foramen ovale,causing severe hypoxemia.Pulmonary vascular remodeling is pathognomonic of hypoxia-induced PPHN.The regulatory mechanism and cell composition of vascular wall were dysfunction,which led to vascular wall thickened.The review focus on three aspects,such as endothelial cells,smooth muscle cells,and adventitial cells,described the relation and the possible mechanisms between hypoxia-induced PPHN and pulmonary vascular remodeling.
3.Effect of Static Balance Test and Training Equipment on Equilibrium Function in Children with Spastic Diplegia
Jingli XU ; Lin LI ; Yanping FAN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):958-959
Objective To observe the effect of static balance test and training equipment on the equilibrium function in children with spastic diplegia.Methods 24 children with spastic diplegia were treated with visual feedback balance training besides routine rehabilitation training.All cases were assessed with Berg Balance Scale(BBS) and the static balance test and training equipment when eyes opened and closed,before and after the 8-week training.Results After the 8 week-training,the BBS scores of all children were higher than that before training(P<0.05).In the segment of the static balance test,fall index,weight distribution index and stability index decreased significantly(P<0.05~0.01).Conclusion The equilibrium function of the children with cerebral palsy can be assessed and pertinent training can be performed with balance equipment.
4.Characteristics of Muscle Tone in Children with Hemiplegic Cerebral Palsy Examined with Surface Electromyography
Jingli XU ; Yanping FAN ; Lin LI
Chinese Journal of Rehabilitation Theory and Practice 2008;14(4):364-365
Objective To explore the surface electromyography(EMG)characteristics of biceps brachii during isometric contraction in children with hemiplegic cerebral palsy.Methods The surface electromyograms signals of biceps brachii of 10 children with hemiplegic cerebral palsy during passive isometric contraction were recorded.Results The intact side registered a stronger EMG than that of the affected side,the integrated electromyography(iEMG)and root mean square(RMS)levels from the intact side were higher than those of affected side significantly(P<0.05).Conclusion The results of electromyographic analysis are consistent with Modified Ashworth Scale.Electromyographic analysis can provide a satisfactory evaluation of the muscle tone in children with hemiplegic cerebral palsy.
5.Application of Surface Electromyography in Rehabilitation for Children with Cerebral Palsy
Jingli XU ; Yanping FAN ; Zaorong DAI
Chinese Journal of Rehabilitation Theory and Practice 2013;19(3):257-260
Objective To explore the surface electromyography (sEMG) assist for the rehabilitation training for children with cerebral palsy. Methods 60 children with spastic diplegia were divided into treatment group (n=30) and control group (n=30). All the children received comprehensive rehabilitation, while the rehabilitation program were designed with the assist of sEMG in the treatment group. They were assessed with Gross Motor Function Measure (GMFM) before and 3 months after rehabilitation. Results There was no statistically improvement in dimension A, B, and C of GMFM (P>0.05), but was in the total score and the dimension D and E (P<0.0001). There was no statistical difference in dimension A, B, and C between 2 groups (P>0.05), but was in the total score and the dimension D and E (P<0.01) after rehabilitation. Conclusion The sEMG might be helpful for the rehabilitation for children with cerebral palsy.
6.An experimental study of casein phosphopeptide-amorphic calcium phosphate on the growth of Lactobacillus fermentum
Xingrong LIU ; Yanping LI ; Ai XU
Journal of Practical Stomatology 2010;26(2):258-259
To investigate the effect of casein phosphopeptide-amorphic calcium phosphate(CPP-ACP) on the growth of Lactobacillus fermentum and to evaluate the possibility of CPP-ACP as a biological anticariogenic agent. Lactobacillus fermentum was inoculated in BHI with different concentrations of CPP-ACP and grew in anaerobic condition at 37 ℃ for 48 h. Used MTT method to evaluate the effects of CPP-ACP on the growth of Lactobacillus fermentum. CPP-ACP inhibited the growth of Lactobacillus fermentum effectively. With the concentration of CPP-ACP increasing, the values of A(550 nm) decreased. It was found that CPP-ACP had inhibitory effect on the growth of Lactobacillus fermentum, the inhibitory effect increased with CPP-ACP concentration.
7.The TCM handbook of AIDS diagnosis and treatment based on evidence-based medicine
Shiping XIE ; Yanping HU ; Qianlei XU
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
By employing the methods of literature research and specialist consultation,comprehensively and systematically collected case history at home and abroad on Chinese and western medicine in the treatment of AIDS,by distilling the etiopathogenisis and pathogenesis,the character,the clinical stage,TCM four methods of examination,di erentiation of symptoms,the therapeutical principle and method and the e ective prescription,etc,the paper clari ed the character,pathology,etiology and pathogenesis of AIDS by the evaluation and statistic of qualitative and quantitative analysis of evidence based medicine,grasped the present situation of the treatment of AIDS with Chinese and western medicine in the treatment of AIDS,the rule of syndrome di erentiation and the facticity and application of the clinical e cacy.All these are used to the TCM handbook of AIDS diagnosis and treatment.
8.Cyto-biocompatibility of two neotype implant titanium alloys
Yanping WEI ; Yantao ZHAO ; Zhixuan XU
Journal of Practical Stomatology 2001;0(01):-
0.05). The cells on Ti1 and Ti2 were attached well till confluent.Conclusion:The neotype titanium alloys are biocompatible.
9.Association between Air Pollutants Exposure during Pregnancy and Preterm Delivery in Taiyuan
Lizhen XU ; Xiaoping XUE ; Yanping ZHANG
Journal of Environment and Health 1992;0(04):-
Objective To investigate the relationship between air pollutant exposure and preterm delivery (PTD) by Logistic regression model, as the effect of air pollutant exposure to PTD made great concern today. Methods The present study consisted of 31 145 qualified birth cases, 80.09% of the total amount, from 1 Nov, 2005 to 1 Aug, 2007. The covariant items included maternal age, nation, education, residence, income, occupation, occupation exposure, parent-drinking, father-smoking, heating-type, folic acid supplement, season of pregnancy, prenatal health care, etc. The Logistic regression analysis was employed to control the confounding factors mentioned above, then the pollutant was introduced step by step to build the single, double and triple pollutant Logistic regression model to examine the association between three pollutants (SO2, NO2, and PM10) and PTD during the first and third trimesters of pregnancy. The air monitoring data (daily average of SO2, NO2, and PM10) were collected from Taiyuan Environmental Monitoring Station. Results In the first trimester, a quartile increase of NO2 exposure caused the risk for PTD increased by 22.7%. As for the effect of PM10, no significant differences were seen. In the third trimester, a quartile increase of NO2 exposure caused the risk for PTD increased by 19.1%. Conclusion The NO2 exposure during the pregnancy can increase the risk of PTD. The susceptible exposure-window choice is critical for the further study in this field.
10.New Resistant Tendency of Urinary Tract Infection
Aihua WEI ; Yanping XU ; Qi ZHANG
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To explore urinary tract infection.METHODS Totally 750 clinical isolates of urinary tract infection were collected from patients who were cured in our hospital from 2001 to 2003,then analyzed the kinds of these bacterials and sensitive rate to antibiotics.RESULTS The percentage of Gram-negative bacilli was 53.60%,in which Escherichia coli was 38.13%;The percentage of Gram-positive cocci was 35.20%,in which Enterococcus were 16.53%;the percentage of fungi was 11.20%.The resistance rate of Escherichia coli to ampicillin,amoxicillin/clavulanic acid,quinolones,nalidixic acid and SXT was 80.54%,57.69%,45.00-71.00%, 71.23% and 65.14%,respectively,and the resistance rate to amikacin was lower than to gentamicin(5.82% vs 39.11%,P