1.Discussion and Application of Medical Matrix on Internet
Chinese Medical Equipment Journal 1993;0(05):-
How to choose appropriate medical matrix and correctly and flexibly master retrieval method are the key factors to get valuable information.The usual medical matrixes on internet are collected and analyzed.According to the requirement of the user,retrieval routes and techniques are introduced.Some advices are also given on the present situation of Chinese medical matrix.The purpose is to help medical personnel to select proper medical matrix for desired information.
2.Discussion on construction of computer room in hospital information center
Chinese Medical Equipment Journal 2004;0(09):-
The construction of standardized and specialized computer room is the base of hospital digitization and informatization.It should follow the national and specialized standards to assure a good condition for the data center,put together the knowledge of multi-disciplines and advanced technologies,and adopt reasonable design and rigid construction.This article discusses the construction of computer room in terms of the principles,elements and co-ordination
3.Crush syndrome in children and the blood purification treatment
Chinese Pediatric Emergency Medicine 2011;18(2):113-115
In the recent years,the earthquake occured frequently in the whole world which caused the increased incidence of crush syndrome (CS). The four limbs and torso will be bleeding and swelling when they are prounded and crushed from the heavy objects. The necrosis of muscular tissue causes massive production of toxin which leads to a series of symptoms including hypotension ,kidney dysfunction and so on. The serious acute kidney injury (AKI) will be vital. When CS-AKI ,the ascending velocity of urea nitrogen and K+ levels in the blood is quicker than those of general AKI;many kinds of immune cells are activated to engender a great deal of inflammatory mediators;the blood dynamics is often unstable. Therefore, it is advocated that the blood purification treatment should be carried early to eliminate excessive metabolic produces in vivo,to reduce the cardiovascular complication occurrence, and to avoid the irreversible change of the kidney function.
4.Pharmacological therapy for post-stroke depression
Lidi WANG ; Guilan LI ; Pengyuan CAO ; Yannan GUO ; Zhongsheng YANG ; Ya’nan CAI
International Journal of Cerebrovascular Diseases 2023;31(11):846-851
Depression is one of the common and serious complications after stroke. Post-stroke depression (PSD) is associated with poor outcomes and increased mortality. The American Heart Association/American Stroke Association guidelines for the early management of patients with acute ischemic stroke recommend that pharmacological therapy should be administered to patients with PSD. This article reviews the pharmacological therapy for PSD.
5.Application of deep learning image reconstruction algorithm in low-dose abdominal CT
Yannan CHENG ; Jingtao SUN ; Yanan LI ; Yinxia GUO ; Le CAO ; Jian YANG ; Jian YANG ; Jianxin GUO
Journal of Xi'an Jiaotong University(Medical Sciences) 2023;44(3):466-472
【Objective】 To investigate the value of deep learning image reconstruction (DLIR) in improving image quality and reducing beam-hardening artifacts of low-dose abdominal CT. 【Methods】 For this study we prospectively enrolled 26 patients (14 males and 12 females, mean age of 60.35±10.89 years old) who underwent CT urography between October 2019 and June 2020. All the patients underwent conventional-dose unenhanced CT and contrast-enhanced CT in the portal venous phase (noise index of 10; volume computed tomographic dose index: 9.61 mGy) and low-dose CT in the excretory phase(noise index of 23; volume computed tomographic dose index: 2.95 mGy). CT images in the excretory phase were reconstructed using four algorithms: ASiR-V 50%, DLIR-L, DLIR-M, and DLIR-H. Repeated measures ANOVA and Kruskal-Wallis H test were used to compare the quantitative (skewness, noise, SNR, CNR) and qualitative (image quality, noise, beam-hardening artifacts) values among the four image groups. Post hoc comparisons were performed using Bonferroni test. 【Results】 In either quantitative or qualitative evaluation, the SNR, CNR, overall image quality score, and noise of DLIR images were similar or better than ASiR-V 50%. In addition, the SNR, CNR, and overall image quality scores increased as the DLIR weight increased, while the noise decreased. There was no statistically significant difference in the distortion artifacts (P=0.776) and contrast-induced beam-hardening artifacts (P=0.881) scores among these groups. 【Conclusion】 Compared with the ASiR-V 50% algorithm, DLIR algorithm, especially DLIR-M and DLIR-H, can significantly improve the image quality of low-dose abdominal CT, but has limitations in reducing contrast-induced beam-hardening artifacts.
6.The effect of CT reconstruction kernels and display window settings on the detection and measurement of pulmonary solid nodules
Yannan CHENG ; Xianjun LI ; Xinyu LI ; Jianying LI ; Le CAO ; Jingtao SUN ; Jian YANG ; Jianxin GUO
Journal of Xi'an Jiaotong University(Medical Sciences) 2022;43(3):476-482
【Objective】 To assess the effect of reconstruction kernels and window settings on the detection and measurement of pulmonary solid nodules and their measurement variability and repeatability. 【Methods】 We retrospectively recruited 49 patients with pulmonary solid nodules who had undergone low-dose CT scanning. Images were reconstructed using five reconstruction kernels: lung, bone, chest, detail and standard kernels. Two radiologists independently assessed the detection rate, diameter and CT number measurement of nodules under the five kernels and two window settings (lung-window and mediastinal-window). Bland-Altman plots and relative average deviation (RAD) were used to evaluate the repeatability and variability of nodule diameter and CT number measurement. 【Results】 Seventy-seven nodules were detected on lung-window regardless of reconstruction kernels, while the detection rates (75.3%-98.7%) were significantly different (P<0.001) on the mediastinal-window, with the lung kernel significantly improving the detection of nodules with the diameter below 6 mm. In both display windows, the diameter and CT number measurements among reconstruction kernels were similar except for the lung kernel. The lung-window had better variability in the diameter measurement while mediastinal-window was better in CT number measurement among various reconstruction kernels. Although the variability in the diameter of the nodule on the lung-window and mediastinal-window was similar, there was a significant difference in the variability in the diameter measurement among different reconstruction kernels on the mediastinal-window (P=0.004). No significant difference in the variability in the CT number measurement was found among the different reconstruction kernels (lung-window P=0.163; mediastinal-window P=0.201), and the variability in the CT number measurements on the mediastinal-window was smaller than that of the lung-window. Both window displays had acceptable repeatability in diameter and CT number measurement; however, the mediastinal-window was better in CT number measurement. 【Conclusion】 The lung kernel can improve the detection of pulmonary solid nodules below 6 mm, but is limited in the CT number measurement. The lung-window display provides better variability in measuring nodule diameter, while mediastinal-window display is better at measuring CT numbers.
7.Case Report and Literature Analysis of Antidepressants-induced Thrombocytopenia
Shuang BAO ; Hongyan ZHUANG ; Shanshan LIU ; Mengxi NIU ; Yannan ZANG ; Xiaoqian LAN ; Fei JIA ; Wei GUO
China Pharmacy 2021;32(3):334-338
OBJECTIVE:To investigate the clini cal features of thrombocytopenia induced by antidepressants ,and to provide reference for the rational use of clinical drugs. METHODS :Retrieved from CNKI ,Wanfang database ,VIP,PubMed and Web of Science,during Jan. 1st in 1985 to Aug. 31st in 2020,case reports about antidepressants-induced thrombocytopenia was collected and analyzed descriptively in terms of demographic characteristics ,medication,clinical manifestations ,treatment and outcome. RESULTS:A total of 17 literatures were retrieved ,and 19 patients were included ,involving 10 male and 9 female,aged from 5 to 95 years old ,with an average of (48±24)years old. Nine kinds of drugs were involved ,including 4 cases of escitalopram ,3 cases of citalopram ,3 cases of fluoxetine ,3 cases of mirtazapine ,2 cases of amitriptyline ,1 case of sertraline ,1 case of paroxetine,1 case of mianserin and 1 case of imipramine. There were 9 cases of single drug and 10 cases of drug combination. All 19 patients suffered from thrombocytopenia at 3 d-10 years after medication ,14 of them had hemorrhage tendency. Main clinical manifestations included mucocutaneous hemorrhage ,gingival bleeding ,black stool ,hematochezia,vaginal bleeding ,ocular hemorrhage,alveolar hemorrhage. No bleeding was found in 5 cases. After drug withdrawal/changing drugs and other symptomatic treatment, platelet count of 19 patients recovered to normal , and bleeding symptoms disappeared. CONCLUSIONS : Thrombocytopenia caused by antidepressants has no obvious clinical features and is not easy to be found ,but it may lead to severe; bleeding symptoms if it is not found in time. The changes of platelet count should be closely monitored in clinical application of such drugs to ensure the safety of drug use.
8. Analysis on the consciousness of the early cancer treatment and its influencing factors among urban residents in China from 2015 to 2017
Huichao LI ; Kun WANG ; Yannan YUAN ; Ayan MAO ; Chengcheng LIU ; Shuo LIU ; Lei YANG ; Huiyao HUANG ; Pei DONG ; Debin WANG ; Guoxiang LIU ; Xianzhen LIAO ; Yana BAI ; Xiaojie SUN ; Jiansong REN ; Li YANG ; Donghua WEI ; Bingbing SONG ; Haike LEI ; Yuqin LIU ; Yongzhen ZHANG ; Siying REN ; Jinyi ZHOU ; Jialin WANG ; Jiyong GONG ; Lianzheng YU ; Yunyong LIU ; Lin ZHU ; Lanwei GUO ; Youqing WANG ; Yutong HE ; Peian LOU ; Bo CAI ; Xiaohua SUN ; Shouling WU ; Xiao QI ; Kai ZHANG ; Ni LI ; Min DAI ; Wanqing CHEN ; Ning WANG ; Wuqi QIU ; Jufang SHI
Chinese Journal of Preventive Medicine 2020;54(1):69-75
Objective:
To understand the consciousness of the cancer early treatment and its demographic and socioeconomic factors.
Methods:
A cross-sectional survey was conducted in 16 provinces covered by the Cancer Screening Program in Urban China (CanSPUC) from 2015 to 2017. A total of 32 257 local residents aged ≥18 years old who could understand the investigation procedure were included in the study by using the cluster sampling method and convenient sampling method. All local residents were categorized into four groups, which contained 15 524 community residents, 8 016 cancer risk assessment/screening population, 2 289 cancer patients and 6 428 occupational population, respectively. The questionnaire collected personal information, the consciousness of the cancer early treatment and relevant factors. The Chi square test was used to compare the difference between the consciousness of the cancer early treatment and relevant factors among the four groups. The logistic regression model was used to analyze the influencing factors related to the consciousness of the cancer early treatment.
Results:
With the assumption of being diagnosed as precancer or cancer, 89.97% of community residents, 91.84% of cancer risk assessment/screening population, 93.00% of cancer patients and 91.52% of occupational population would accept active treatments (