Objective To research the relationship between hypertensive disorder complicating pregnancy and serum free estriol 3 (FE3) and explore its impact on pregnancy outcome.Methods Clinical data of 117 hypertensive disorder complicating pregnancy and 165 normal pregnant women were retrospectivly analyzed.Chemiluminescence immunoassay determination of maternal serum FE3 also had been conducted.Then analyzing the correlation between hypertensive disorder complicating pregnancy and FE3 and its impact on pregnancy outcomes.Results LDL cholesterol and the level of creatinine of observation group were significantly lower than the control group(t =3.129,9.372,all P ＜ 0.05),while blood pressure,triglycerides,HDL,and 24-hour urinary protein content were significantly higher than control groug(t =7.361,2.398,2.833,all P ＜ 0.05).The FE3 level of the observation group were significantly lower than the control group (t =2.913,P ＜ 0.05).There was a significant positive correlation between the FE3 level of normal pregnant women and their gestational age (r =0.937,P ＜ 0.05).The probabilities of premature birth,premature rupture of membranes,postpartum hemorrhage,and neonatal asphyxia of observation group were significantly higher than amtrol group (x2 =3.912,3.879,4.267,6.935,all P ＜ 0.05).Conclusion There is a significant correlation between hypertensive disorder complicating pregnancy and FE3,which has an important significance on monitoring the health status of pregnant women and the fetal-placental function.

Objective To study the safety and effect of interventional treatment for arteriesclerotic obliterations of iliaco-fermoral artery via radial artery retrospectively.Methods Sixteen cages were treated with interventional procedare via radial artery.The duration of disease was from 3 days to 2 years.All cases presented with rest pain and intermittent claudicating(with distance less than 500 m).Unilateral lesions were found in 9 cases.and bilateral lesions in 7 cases.Iliaco-femoral arteries were obliterated completely in 6 cases.while the other ten cases had arterial stenesis more than 75%.After visualization of obliterative artery.urokinase was administrated consecutively from catheter indweUed in or above thrombus.Transcatheter thrombolysis would be cancelled if the therapeutic effect wag negligible after using umkinase for 72 hours.After thrombolysis.the balloon angioplasty and the stent implantation were performed in the cases with residual stenesis more than 50%. In all of 16 cases,5 caseg underwent continuous intraarterial thrombolysis only.11 cases received balloon angioplasty and/or stent implantation additionally.The ankle/braehial index(ABI)post-treatment and pre-treatment was analyzed.Results The duration of transcatheter thrombolysis was 3.0-15.0 days,averaged(8.4±2.9)days.The obliterative arteries were recanalized in 15 cases.The symptoms of rest pain disappeared in all cases.while intermittent claudicating was still present in 4 cases,but the claudicating distance increased significantly(92.50±60.21 and 625.00±84.26 m for pre-and post-operation respectively).The ABl was 0.63-1.10(0.91±0.12)for post-treatment and 0-4).57(0.32±0.14)for pre-treatment respectively(t=21.73,P＜0.01).During 6-24 months' follow-up,restenosis occurred in 1 case,which was treated successfully once again after halloon angioplasty.There was no serious complication related to the procedure.Conclusion It is safe and effective to apply continuous thrombolysis combined with balloon angioplasty and stent implantation to treat iliacofemoral artery obliteration interventionally via radial arterv.

Objective? To understand the situation of urinary incontinence and quality of life among patients with post-laparoscopic radical prostatectomy and to analyze the correlation between them. Methods? From September 2015 to October 2016, we selected 115 patients with post-laparoscopic radical prostatectomy at a ClassⅢ Grade A hospital in Beijing for survey by questionnaire with the method of convenience sampling. We collected patients' general information as well as disease information, and evaluated the situation of urinary incontinence (incidence and severity of urinary incontinence) with the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and influence of urinary incontinence on quality of life with the Incontinence Impact Questionnaire (IIQ-7) to analyze the correlation between severity of urinary incontinence and quality of life. Results? Among 115 patients with post-laparoscopic radical prostatectomy, there were 95 (82.6%) urinary incontinence patients including 41 cases (43.1%) with mild urinary incontinence, 47 cases (49.5%) with medium urinary incontinence and 7 cases (7.4%) with severe urinary incontinence. The score of severity of urinary incontinence ranged from 0 to 19.0 with 8.0 for the median and 5.0 for the interquartile range. Spearman correlation analysis showed that the score of IIQ-7 had a positive correlation with the severity of urinary incontinence (r=0.674, P＜0.01), and had a negative correlation with the postoperative time (r=-0.215, P＜0.05). Multiple linear regression analysis showed that the main influencing factor of quality of life was severity of urinary incontinence (P＜0.01). Conclusions? Urinary incontinence is common among patients with post-laparoscopic radical prostatectomy mainly in mild and medium urinary incontinence. The more serious the urinary incontinence is,the greater the influence on quality of life is which points out that the scientific and effective management by medical staff for urinary incontinence can improve patients' quality of life.

Objective:To explore the status quo and influencing factors of nursing staff's nursing informatics competencies and provide reference for the relevant departments of the hospital and nursing managers to cultivate their informatics competencies.Methods:In this cross-sectional study, from July 31 to August 12, 2019, totally 982 nurses from Peking University First Hospital were selected by convenient sampling and investigated with the General Informatics Questionnaire and Nursing Informatics Competency Scale. Multiple linear regression analysis was used to analyze the influencing factors of nursing informatics competencies. A total of 982 questionnaires were distributed in this study, and 982 valid questionnaires were recovered, with an effective recovery rate of 100%.Results:The total score of nursing informatics competencies of the 982 nurses was (125.61±22.79) , including (45.70±9.74) for informatics management ability, (31.83±6.08) for computer operation ability, (20.16±4.07) for computer software management ability, (15.54±3.23) for nursing informatics awareness, and (12.37±2.49) for nursing informatics operation ability. The multiple linear regression analysis showed that age, education, department and whether they had received informatics-related training were the main factors affecting their nursing informatics competencies ( P<0.05) . Conclusions:The nursing informatics competencies of the nursing staff of Peking University First Hospital is satisfactory. Age, education, department and whether they have received informatics-related training may affect their nursing informatics competencies. It is suggested that hospital managers and relevant departments should provide more individualized training for personnel of different age groups, different educational backgrounds and different departments.

Objective To explore the barriers in the clinical use of evidence-based urethral catheter cleaning. MethodsThe interview outline was developed based on the Theoretical Domains Framework (TDF) from September to October 2018. Totally 19 nurses working in the Department of Urinary Surgery at Peking University First Hospital was selected for semi-structural interview by convenient sampling, and content analysis was conducted based on the results. ResultsA total of 4 barriers related to 4 domains under the TDF were found in this study, namely, social / professional roles and identities, confidence in results, environmental factors and resources, and social impact. The subjects were extracted on this basis, which were lack of knowledge conversion process and norms in the department, poor self-management ability in the patients, and insufficient catheter cleaning resources. ConclusionsThe clinical use of evidence-based urethral catheter cleaning is affected by multiple factors, including systems, patients and resource availability. Departments need to explore and develop the norms for knowledge transformation, improve the self-management ability of postoperative patients, provide sufficient resources for catheter cleaning, and promote the clinical use of evidence-based urethral catheter cleaning.

Objective:To find out the obstacle factors in its clinical application according to the clinical situation of the application of urinary catheter fixation device.Methods:From September 2018 to October 2018, 19 nurses working in the urology ward of Peking University First Hospital were selected for a semi-structured interview. Based on the theoretical domain framework, the interview outline was formulated and the content was analyzed, and the topic was extracted again.Results:This study identified obstacle factors related to 5 areas of the theoretical domain framework, namely "knowledge, social or professional role and identity, motivation and goals, environmental factors and social influence". The themes were extracted again, respectively: "the system level of evidence implementation (organizational factors, training, product categories) needs to be optimized, the level of willingness of users (patients) for evidence implementation needs to be improved and the sustainability of evidence application needs to be strengthened".Conclusions:The factors that affect the clinical application of urinary catheter fixation devices are multiple, and future research needs to formulate targeted intervention plans based on evidence according to obstacles identified.

Objective To investigate the knowledge and behavioral status of foot care among pa-tients with type 2 diabetes in Xinjiekou Community in Beijing and analyze its influencing factors.Methods A convenient sampling method was used to select 278 diabetes patients from Xinjiekou Community in Beijing for questionnaire surveys,which included general information,foot care knowl-edge,and behaviors of the patients.Results The average score of foot care knowledge among the 278 patients was(71.65±14.59),indicating a moderate level overall.The average score of foot care be-havior was(48.83±8.83),indicating a poor level overall.Multivariate stepwise regression analysis showed that gender,duration of diabetes,and whether the patients had received foot care education or not were independent influencing factors for both the foot care knowledge score and the foot care behav-ior score among community diabetes patients(P＜0.05).Pearson correlation analysis showed that a positive correlation between foot care knowledge and foot care behavior among community diabetes patients was observed(r=0.593,P＜0.001).Conclusion The level of foocare knowledge among diabetes patients in this community in Beijing is moderate,while the status of foot care behaviors is not optimistic.Community healthcare professionals should strengthen health education on foot care,improve patients'knowledge of foot care and compliance with foot care behaviors,and pay attention to male patients and those with a shorter duration of diabetes to reduce the occurrence of diabetic foot.

Objective To investigate the knowledge and behavioral status of foot care among pa-tients with type 2 diabetes in Xinjiekou Community in Beijing and analyze its influencing factors.Methods A convenient sampling method was used to select 278 diabetes patients from Xinjiekou Community in Beijing for questionnaire surveys,which included general information,foot care knowl-edge,and behaviors of the patients.Results The average score of foot care knowledge among the 278 patients was(71.65±14.59),indicating a moderate level overall.The average score of foot care be-havior was(48.83±8.83),indicating a poor level overall.Multivariate stepwise regression analysis showed that gender,duration of diabetes,and whether the patients had received foot care education or not were independent influencing factors for both the foot care knowledge score and the foot care behav-ior score among community diabetes patients(P＜0.05).Pearson correlation analysis showed that a positive correlation between foot care knowledge and foot care behavior among community diabetes patients was observed(r=0.593,P＜0.001).Conclusion The level of foocare knowledge among diabetes patients in this community in Beijing is moderate,while the status of foot care behaviors is not optimistic.Community healthcare professionals should strengthen health education on foot care,improve patients'knowledge of foot care and compliance with foot care behaviors,and pay attention to male patients and those with a shorter duration of diabetes to reduce the occurrence of diabetic foot.

Outpatient humanistic care refered to providing a full process of caring medical services to outpatients. In order to standardize the human caring services for outpatients in medical institutions, promote the comprehensive service level of outpatient services, and improve the patient′s medical experience, Chinese Association for Life Care issued the group standard of Management Norms for Human caring of Outpatients in April 2023. This standard clarified the relevant terms and definitions of human caring for outpatients, specified the basic requirements for human caring, the humanistic quality and care responsibilities of outpatient staff, the outpatient care environment and facilities, the outpatient care process and measures, and quality management. It designed standardized and personalized full process care service norms, providing references for medical institutions at all levels to promote the development of human caring for outpatients.