1.Discussion on Foreign Traditional Medical Information Monitoring Process and Mode
Yanmin HU ; Meng CUI ; Yingkai ZHAO
International Journal of Traditional Chinese Medicine 2009;31(4):360-361
With the rapid development of internet and computer technology, the interact has become the richest information resource of the world, and there comes a large potential and broad prospect for the development of internet medium information monitoring. In this paper, we discuss the information monitoring mode of foreign traditional medicine which released by the internet medium. We will discuss the monitoring mode in five steps: automatic information collection-information classification and storage-"human-computer cooperated" data processing and information analysis-dynamic output of information- information feedback.
2.Research progress on surface modification of titanium and titanium alloys by ion implantation
Jiao FANG ; Yanmin ZHOU ; Jinghui ZHAO
Journal of Practical Stomatology 2014;(4):560-563
Ionimplantationtechniqueisamethodthatprocessingthematerialsurfacesinordertochangetheirsurfacechemical,physical and mechanical properties in vacuum environment.Titanium and titanium alloys modified by different types of ions can change their surface properties and characteristics,thereby improving the osseointegration and antibacterial properties of titanium implant.This review summarizes the researches of titanium implant surface modified by different ions implanting.
3.Review on the research progress of Ayurvedic medicine
Yanmin HU ; Meng CUI ; Yingkai ZHAO
International Journal of Traditional Chinese Medicine 2013;35(10):868-874
This paper reviewed the research progress of Ayurvedic medicine in domestic and abroad.The main contents included:the research progress of ayurvedic ancient records and basic theories,morden pharmacological studies,experimental and clinical studies,etc.
4.Curative effects observatin of Edaravone on the patients with acute massive cerebral infarction
Yanmin ZHAO ; Zhongpeng FAN ; Pin CHEN
Journal of Clinical Neurology 2001;0(05):-
Objective To observe the curative effects of treatment with Edaravone for acute massive cerebral infarction.Methods 48 patients with acute massive cerebral infarction were randomized into the treatment with Edaravone group(Edaravone group,24 patients) and the conventional treatment control group(control group,24 patients).Two groups patients were admitted conventional treatment for cerebral infarction.Edaravone group patients were admitted with Edaravone 30 mg into 100 ml saline infusion introvenously,twice a day,linked 20 ~ 25 d.Respectively before and after the treatment,neurologic function dificit score(NDS),plasma fibrinogen(Fib) content,coagulation blood function,activity of superoxide dismutase(SOD) were examined.The clinical efficacy was compared between the two groups.Results NDS of tow groups after treatment were significantly lower than those of before treatment,activity of SOD were significantly increased than those before treatment(all P0.05).Significant efficiency ratio of the Edaravone group(87.5%) was significantly higher than that of the control group(45.8%)(P
5.Study on mechanisms of gastrointestinal symptoms in renal insufficiency
Yanmin CHEN ; Shi ZHAO ; Hong FAN
Chinese Journal of Digestion 2001;0(09):-
Objective To investigate the gastric empty and electrogastrogram(EGG) in patients with renal insufficiency before and after hemodialysis, and to study the enteric nervous system (ENS) in experimental acute renal failure rats.Methods The comparisons of gastric emptying and EGG before and after hemodialysis were carried out in 15 patients with uremia who have gastrointerstinal symptoms. Acute renal failure models were also established. The neuroplexus of ENS and levels of some gut hormones were investigated. Results The EGG and gastric emptying were abnormal in patients with uremia before hemodialysis, but improved after dialysis. The neuroplexus of ENS with positive nitric oxide synthase(NOS) staining in rats with acute renal failure was significantly decreased. The levels of gastrin, vasoactive intestinal peptide and motilin in rats with acute renal failure were (159.1?55.6)?g/L, (121.6?48.9)pg/L, and (6.32?3.55)pmol/L, respectively, which were significantly different from those of the control group(P
6.Finite element analysis of three kinds of implants with different pitches under concentrated load
Jinghui ZHAO ; Yanmin ZHOU ; Yunliang ZHAO ; Chunyan LI
Journal of Practical Stomatology 2009;25(6):820-823
Objective; To investigate the stress distribution in implant-bone interface with different pitches by three-dimension finite element analysis method in order to decide the best design of thread parameters for stress distribution. Methods: Built three-dimension finite element models of partial mandible and dental implant with superstructure. The stress distributions in bone and three kinds of implants whose pitches were 0.6, 0.8 and 1.0 mm respectively, under axial and oblique 45 degree to axle concentrated load. Data were analyzed by Cosmos/works software. Results;The maximal Von-Mises stress, tensile stress and compressive stress of implant with 0.8 mm pitch were lower than others, the stress distribution was even. The stresses in the same model under oblique load were much higher than those under axial load. The stress concentrated more on implant neck, upper part of cortical bone and the lowest thread on implant. Conclusion; The pitch of implant has effect on stress distribution in implant-bone interface and the transmission of occlusal force. The lower threads on implant should be cut to avoid the concentration of stress, and the non-axial force should be reduced as possible as we can or avoided when we design and make implant denture.
7.Polysorbate-80 modified neurotoxin nanoparticle with its transport and cytotoxicity against blood-brain barrier.
Yanmin ZHAO ; Aixiao XIA ; Yinghui WEI ; Yeping RUAN ; Fanzhu LI
Acta Pharmaceutica Sinica 2010;45(10):1312-6
This study was aimed at the transport across blood-brain barrier (BBB) of polysorbate-80 modified neurotoxin loaded polybutylcyanoacrylate nanoparticle (P-80-NT-NP) and its cytotoxicity. An in vitro model of BBB using rat brain microvascular endothelial cells (rBMECs) was established. The cytotoxicity of P-80-NT-NP was measured by the MTT assays, where neurotoxin (NT), nanoparticle (NP), neurotoxin nanoparticle (NT-NP) as control, and the permeability of P-80-NT-NP was determined by using of Millicell insert coculture with rBMECs and fluorescence spectrophotometry. MTT results showed that NT, NP, NT-NP and P-80-NT-NP were avirulent to rBMECs when the concentration of NT was lower than 200 ng x mL(-1). But the cytotoxicity of NP, NT-NP and P-80-NT-NP would be augmented accordingly as concentration increased (P < 0.01), causing obvious reductions of cell survival rate, with no significant difference between them (P > 0.05). When the concentration of NT was 150 ng x mL(-1), the permeability on rBMECs of P-80-NT-NP and NT-NP were both significantly higher than that of NT (P < 0.01), and the permeability of P-80-NT-NP was greater than that of NT-NP (P < 0.05). In conclusion, polysorbate-80 modified neurotoxin nanoparticles can transport across the BBB, while concentration of NT is greater than 200 ng x mL(-1), P-80-NT-NP has a little cytotoxicity against rBMECs.
8.Risk factors and treatment of intraoperative femur fracture in hip replacement
Yanmin BU ; Tieliang ZHANG ; Xiuxiang ZHAO ; Jianhua YU ; Dezhi ZHENG
Chinese Journal of Trauma 2010;26(12):1118-1121
Objective To analyze the risk factors related to intraoperative femur fracture in hip replacement and discuss the treatment countermeasures. Methods The medical records and radiographs of 38 patients with intraoperative femur fracture who were treated at Tianjin Orthopedic Hospital from December 2002 to December 2009 were retrospectively studied. Fractures were classified according to the Amstutz system or AAOS standard and the treatment methods were selected accordingly. Reduction and fixation was performed in 25 patients including 14 patients treated with interfragmentary or cerclage fixation, five with plate fixations and six with cortical strut graft. Shank prosthesis was replaced in 12 patients. Results The mean follow up period was 4.5 years, which showed successful union of the fractures in 36 patients and delayed union in two. Replacement of the prosthesis was needed in one patient for prosthesis loosening four years postoperatively. Conclusions Osteoporosis, violence, abnormal femur canal and over large prosthesis are the main causes of intraoperative femur fracture in hip replacement.Proper selection of treatment method according to fracture types may attain fracture union with a stable implant.
9.Periacetabular osteotomy for the treatment of developmental dysplasia of the hip in adults
Xiuxiang ZHAO ; Jianhua YU ; Yanmin BU ; Dezhi ZHENG ; Tieliang ZHANG
Chinese Journal of Orthopaedics 2010;30(10):961-966
ObjectiveTo study the indications and mid-term outcomes of periacetabular osteotomy on adult patients of developmental dysplasia of the hip (DDH). MethodsTwenty-five adult patients with DDH underwent periacetabular osteotomies through modified Smith-Peterson approach. There were 19 females and 6 males with an average age of 25.5 years(range, 18-45). Every patient had a single dysplasia hip, including 14 hips in the left, and the other 11 in the right. Three cases were operated formerly, 2 of them received Chari osteotomy and 1 received Salter osteotomy. Before operation 13 hips were T(o)nnis Grade 0 osteoarthritis, 9 hips were Grade Ⅰ , 3 hips were Grade Ⅱ. The Shenton line of 18 hips was broken. The lateral center-edge angle was 4.57°±7.39°, the anterior center-edge angle was 0.95°±6.02°, the horizontal tilt angle was 32.50°±5.96°, the femoral head extrusion index was 38.11%±5.70%, the Harris hip score was 75.32±7.51 points. Changes of the indexes mentioned above were observed during the period of follow-up.ResultsAll patients were followed up for average 4.5 years(range, 2.0-7.5). Compared with the preoperative radiographic severity at the latest follow-up, 3 hips of T(o)nnis Grade Ⅰ improved to Grade 0, 2 hips of Grade Ⅱ improved to Grade Ⅰ, 1 hip of Grade Ⅰ changed into Grade Ⅱ. The incident of the break of Shenton line decreased to 10 hips. The lateral center-edge angle improved to 29.07°±5.81° the anterior centeredge angle improved to 29.52°±4.51°, the horizontal tilt angle decreased to 19.17°±4.95°, the femoral head extrusion index decreased to 24.20%±4.83%, the Harris hip score increased to 84.88±4.88 points. The major complication included 16 cases of lateral femoral cutaneous nerve palsy(7 cases of them didn't recover forever) and 1 case of ectopic ossification of Brooker Ⅰ . ConclusionPeriacetabular osteotomy through a modified Smith-Peterson approach were performed to the dysplasia hip of adults, it can increase congruence,improve hip function; it can also prevent subchondral sclerosis and cysts forming, preserve joint space and delay the occurrence of osteoarthritis.
10.Current situation analysis on resource and service of traditional medicine of China and India
Yanmin HU ; Meng CUI ; Yingkai ZHAO ; Xiaoling WU ; Ming XUE
International Journal of Traditional Chinese Medicine 2014;36(3):197-200
Objective To Analyze the development tendency and major influential factors of the resource and service of traditional medicine (TM) by contrasting the statistical data between China and India.Methods The research data came from the governmental statistical date of traditional medicine.The main statistical indicators included:number of TM hospitals,number of beds in TM institutions,number of health personnel of TM,number of visits and inpatients of TM institutions.A contrastive analysis was given based on these data over the period of 2008-2012.Results In 2012,the number of traditional Chinese medicine (TCM) hospital per ten million populations was 25.1,the number of Traditional Indian Medicine (TIM) hospital per ten million populations was 25.9; the number of beds in TCM institutions per ten thousand populations was 4.5,the number of beds in TIM institutions per ten thousand populations was 0.5; the number of TCM physicians and physician assistants per ten thousand populations was 2.6,the number of TIM physicians and physician assistants per ten thousand populations was 5.9.In 2012,the numbers of visits and inpatients of governmental public TCM hospitals were 426.671 million and 16.882 million; the numbers of visits and inpatients of governmental public TIM hospitals were 73.445 million and 0.947 million.Conclusion There was no significant difference in the number of TM hospitals per ten million populations between China and India.China had obviously advantages in the number of beds in TM institutions,number of visits and inpatients of TM institution.India had obviously advantages in the number of TM health personnel.