The health system in Shanghai selected 102 prominent middle aged and young health personnel with both political integrity and professional competence as candidates for its program of cultivating 100 outstanding cross century academic leaders. Program starting funds were provided by the Health Bureau of the city and cultivation plans were worked out and contracts signed together with the institutions the candidates work with and competent authorities at higher levels so as to ensure the implementation of the cultivation measures and the whole course follow up and assessment of the candidates actual professional expertise, organizational and managerial capabilities, academic positions, notability enhancement, and actual performance in patient care, teaching and research. Performance analysis indicates that after 5 to 7 years of special training, the candidates have turned into the citys new generation of advantaged academic leaders and have helped to push the development of the health cause and the quality of patient care in Shanghai to a generally higher level.