1.The scalfold materials of bone tissue engineering
International Journal of Biomedical Engineering 2001;24(2):73-77
To explore the ideal scalfold materials is one of the popular studies on current bone tissue engineering. This paper rewiewed current studies on artificial synthetic biomaterials、natural biological organism derived materials and thier composited materials which used as bone tissue engineering scalfold materials. This paper also intruduced the virtues and defects of these materials,illustrated the questions would be disolved and developing trends on bone tissue engineering scalfold materials in the future.
2.Performance and clinical application of endovascular stent materials
Chinese Journal of Tissue Engineering Research 2009;13(51):10153-10156
OBJECTIVE: To investigate clinical application of endovascular stents, to evaluate materials performance, and to study in-stent restenosis.METHODS: A computer-based online search was conducted in CNKI and Medline database with the key words of "endovascular stent, materials, application'' in both Chinese and English from 1960 to 2009. Among 67 articles, 31 references were included according to inclusion and exclusion criteria. All the included references were summarized based on application range of endovascular stent, stent materials, in-stent restenosis so as to investigate clinical application and performance of endovascular stent.RESULTS: Endovascular stent had been widely used to treat coronary atherosclerotic heart disease, intracranial aneurysm, symptomatic or non-symptomatic ischemic cerebrovascular disease, and peripheral angiopathy. Varying endovascular stent materials, such as metal, tissue-engineered, and drug-coating had remarkably therapeutic effect; in particular, biocompatibility and blood compatibility of drug-coating stent were superior to those of others. With the functional development of endovascular stent, more and more stents will be used for clinical therapy; however, restenosis and immunological rejection still remain unsolved.CONCLUSION: Endovascular stent has been widely used to treat varying cardio-cerebrovascular disease. Biocompatibility of drug-coating stent is superior to that of other stent materials. Endovascular stent with a great biocompatibility or Probucol-coating stent may reduce the incidence of restenosis.
3.Effect of pulmkort respule combined with solution salbutamol aerosol on bronchiolitis
Yanlin LI ; Xiaoping WU ; Wenjun LI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(8):1279-1280
Objective To evlauate the effect of pulmicort respule combined with solution salbutamoI aerosol on the treatment of bronehiolitis.Methods 65 cases of bronchioiltis were randomly divided into two groups.solution saltutamol inhalation group or pulmicort respule combined with solution salbutamoI group,the time of easing asthma symtpoms was assessed.Results Therapeutic group cure rate is higher than the control group(87.9%/62.5%,P<0.01),there is significant difference.Observation group duration of symptoms was significantly shorter than the oontrol group(P<0.01),the difference is significant.Condmlon Pulmicort respule combined with solution salbutamol has significant therapeutic effect on the treatment of bronchiolitks,there are obvious advantages.
4.Clinical analysis of 88 eases neonatal hypoxic-ischemic encephalopathy
Yanlin LI ; Xiaoping WU ; Wenjun LI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(6):952-953
ObjectiveTo discuss neonatal hypoxic-ischemie eneephalopathy points,and the vesting of the re- lationship between the prognosis and current treatment methods. MethodsFrom January 2004 to April 2008, pedi-atric hospital treated 88 cases of HIE were assessed, inspected, grading and treated. Results8 cases in the 88 easesantomatically discharged, 51 patients (63.8 %) were recovered and 28 patients (35.0 %) improved, and 1 patient(1.3 %) died. HIE clinical severity has close relationship with prognosis. Mild and moderate cases were 78.4 % (29/37) ,53.7% (22/41) were recovered and no deaths, and severe 1 case, 1 death. ConchtsionHIE clinical severityand prognosis have close relationship, the time of birth asphyxia situation on the vesting of infants discharged andwas no significant impact.
5.Primary cardiac schwannoma-a case report and literature review
Yanlin CHU ; Yingyu WU ; Tongxun LI
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(02):-
Objective: To report one case of primary cardiac schwannoma (PCS) with review of literature. Methods: One patient with primary malignant cardiac schwannoma (PMCS) was treated surgically in our hospital and relevant data of 18 cases were collected from international literature. Clinical features, diagnosis and surgical treatment of PCS were discussed. Results: 17 cases were PMCS and 2 cases were primary benign cardiac schwannoma (PBCS). Operation was performed in 11 cases. The locations of mass were both superior vena cava and right atrium in 2 cases, inferior vena cava and right atrium in 1, pulmonary vein and left atrium in 1, right atrium in 1, left atrium in 3, right ventricular outflow tract in 2, and intrapericardial in 1. The long-term results for resected PCS were excellent, but for PMCS were very poor. Conclusion: PCS is an extremely rare disease. The diagnosis dependents on clinical features, M-mode and two-dimensional echocardiography, magnetic resonance imaging, and histopathological and immunohistochemical findings. It is concluded that most PBCS can be resected completely with good results. PMCS can not be resected completely either because of the extent spread and invasion or frequent distant metastasis. The prognosis is dismal and early cardiac transplantation probably offers the only hope for patients with PMCS.
6.Progress in cognitive dysfunction induced by radiotherapy in patients with nasopharyngeal carcinoma
Ling LI ; Ling QIN ; Yanlin MO
Cancer Research and Clinic 2016;28(10):716-720
Radiotherapy (RT) is the primary treatment for nasopharyngeal carcinoma (NPC). In order to achieve tumor control, nearby normal brain tissues, especially the temporal lobes, often receive unnecessary radiation. Patients with NPC treated by RT may occur cognitive impairments, which significantly compromises the quality of life. The symptoms of cognitive dysfunction induced by RT in NPC patients can exhibit at the early or later stage after RT, which may be related to temporal lobe injury or brain damage induced by radiation. However, the relationship between the cognitive declines induced by RT and the radiation dose or volume of the temporal lobe (or the dosimetry to treat NPC) has not yet been definitively established, and few reports have focused on cognitive impairment following intensity modulated RT. Therefore, this paper will review the progress in radiation-induced cognitive decline of NPC patients in order to provide the basis for preventing side effects of RT and improving the quality of life after RT.
7."Technical Design of Interface between""No.1 Military Medical Project""and the New Rural Coadjutant Medical Care System"
Zhiyong LI ; Yue ZHANG ; Yanlin LIU
Journal of Medical Informatics 2015;(7):29-32
Taking 201 Hospital of PLA as an example, the paper introduces the design of interface betweenNo.1 Military Medical Projectand the New Rural Coadjutant Medical Care ( NRCMC) system from the aspects of interface system constitution and technical design, etc.The system runs smoothly since application, promotes business dealings between hospital and NRCMC center, and it is worth promotion.
8.Efficacy of emergent intracoronary transplantation of bone marrow mononuclear cells for treatment of acute myocardial infarction (TCT-STAMI)
Yanlin LI ; Junbo GE ; Juying QIAN
Chinese Journal of Interventional Cardiology 1993;0(03):-
0.05) in the BMT group but significantly enlarged in the CON group (50.4?6.0 mm vs. 55.2?7.1 mm, P
9.Preparing of biphasic ceramic biologic active bone BCBB/BMP/bFGF and the study of its biocompatibility with rabbit bone mesenchymal stem cells
Wuxun PENG ; Lei WANG ; Yanlin LI
Orthopedic Journal of China 2006;0(19):-
[Objective]To prepare a kind of biphasic ceramic biologic active bone and study its biocompatibility.[Method]Biphasic ceramic biologic bone(BCBB) was mixed with collage type I,bone morphogenetic protein(BMP) and basic fibroblast growth factor(bFGF),and then the third generation cultured rabbit bone mesenchymal stem cells(MSCs) were seeded on BCBB/BMP/bFGF in vitro.The tissue engineering bone(BCBB/BMP/bFGF/MSCs) was observed by upside down microscope,scanning electron microscope(SEM) and examined using methylthiazol tetrazolium(MTT).[Result]Biphasic ceramic biologic active bone BCBB/BMP/bFGF was successfully prepared by reconstituting collage type I,BMP,bFGF and BCBB together.The rabbit cells grew in and on the BCBB/BMP/bFGF to form an ideal tissue engineering bone,and the cells quantity was the most on the 6th day.[Conclusion]BCBB/BMP/bFGF possesses a good biocompatibility with rabbit bone mesenchymal stem cells.