Attention deficit hyperactivity disorder(ADHD) is one of the most common psychiatric illness in children. The symptoms in ADHD are inatention, hyperactivity and impulsivity.It interferes with many areas, such as family life, personal achievement and relationship ability.There have been no objective methods to diagnose ADHD and evaluate the treatment effect by far.EEG can reflect brain function non-invasively.This review summarizes the progresses of quantitative electroencephalography in ADHD.

Objective To know the present status of the clean operating rooms in some hospitals in Shanxi province. Methods 8 indices including clean efficiency of newly built operating room were monitored during 2005-2006. Results The results showed that the overall eligible rate was 67.3%, of which the eligible rate of wind speed(air change rate)was 68.2%, humidity was 61.4%, suspend particle was 94.5%, noise was 95.5%, illuminance was 100%, temperature was 100%, differential pressure was100%, airborne bacterial was 100%, depositing bacterial was 100%. Conclusion In operating rooms, the eligible rate of biological indices is the highest and the eligible rate of purification is lower. The eligible rate of technology indices is the lowest.

Objective To investigate the prevalence of fatigue in AS and its relationship with other clinical and functional parameters used for the evaluation of disease activity. Methods The fatigue was assessed in 73 patients with active AS using a single-item fatigue question of BASDAI. The correlation between fatigue and the clinical parameters of disease including the Bath AS disease activity index(BASDAI), Bath AS functional index (BASFI), Bath AS metrology index(BASMI), night pain, spinal inflammation, patient's global assessment(PGA) and enthesis index(EI) were determined. Results A total of 73 patients with ankylosing spondylitis were recruited. The prevalence of fatigue was 90.4% and the fatigue score of 68.5% patients was higher than 5. After controlled for the possible confounding factors such as age, gender, age and disease duration, it was found that fatigue was highly correlated with disease activity, pain and functional disability, BASMI,physical health and mental health. Conclusion Fatigue is an important symptom in AS. Fatigue can be measured with a single-item fatigue question of BASDAI.

Objective To investigate the clinical efficacy of piracetam combined with edaravone in the treatment of patients with acute cerebral infarction.Methods 120 patients with acute cerebral infarction were selected,and they were randomly divided into control group and observation group according to the digital table,60 cases in each group.The patients in both two groups were treated with mannitol to reduce intracranial pressure,aspirin antiplatelet aggregation,combined with basic nutritional support,active prevention and treatment of complications.The control group was intravenously given piracetam.On this basis,the observation group was intravenously given edaravone injection.Both two groups were treated for 14 days.The clinical curative effect,neurological deficit and self-care ability score before and after treatment were observed,and the indicators of hemorheology before and after treatment were observed.Results Mter treatment,the neurological deficit and self-care ability scores of the two groups were significantly improved(t =3.43,4.12,5.67,6.89,all P ＜ 0.05),the improvements of the observation group were significantly better than those of the control group(t =2.10,4.21,all P ＜ 0.05).The total effective rate of the observation group was 85.00％,which was higher than 70.00％ of the control group,the difference was statistically significant (x2 =4.11,P ＜ 0.05).After treatment,the indicators of hemorheology of the two groups were significantly improved (t =1.43,2.98,2.32,4.56,1.67,2.11,1.46,1.98,all P ＜ 0.05),and the improvements of the observation group were significantly better than those of the control group (t =1.46,2.32,1.67,1.39,all P ＜ 0.05).Conclusion Piracetam combined with edaravone can significantly improve the neurological function,cognitive function and hemorheology of patients with acute cerebral infarction.

Objective To explore the difference of cognitive function and psychosocial function between remitted bipolar disorder(BPD) and remitted schizophrenia.Methods 8 neuropsychological tests (17 items)which evaluate attention,verbal learning and memory,visual memery and executive function were given to 30 remitted BPD,32 remitted schizophrenia and 34 normal controls.The differences of cognitive functions between the three groups were compared using multivariate analysis of variance (MANOVA).Psychosocial functions of remitted BPD and remitted schizophrenia were both evaluated by Global Assessment Function (GAF),and the difference of Psychosocial functions between the two groups was also tested by MANOVA.Results1.Remitted schizophrenia showed dysfunction in neuropsychological tests except Stroop C and digit span subtest-forward compared with controis.but Remitted BPD only showed dysfunction in 9 neuropsychological items compared with controls.There was no significantly differences on WCST,digit span subtest-backward,and TMT-B between remitted BPD and remitted schizophrenia,the degree of impairment of the two groups was same.But scores from logical memory sub-test and Stroop CW of remitted schizophrenia were significantly lower than that of remitted BPD( ( 8.13 ± 3.35),( 12.11 ±3.72),(6.00 ±3.09),(9.78 ±3.60);(48.61±15.73),(69.33 ±21.04),P＜0.05).There was significant difference on scores of GAF between remitted BPD and remitted schizophrenia.Conclusion There are some overlap in cognitive impairment in remitted BPD and remitted schizophrenia,but in remitted schizophrenia the cognitive profile is characterized by generalized and severer pattern of deficits.The psychosocial function of remitted BPD is better than that of remitted schizophrenia.

Object To establish a SDS PAGE method on quality control of melittin. Methods Melittin was extracted and purified from bee venom by gel chromatography. Purity and molecular mass of melittin were determined by SDS PAGE. Results In the gelatinous board, the sample was a single peptide chain with a molecular mass of about 2 800 dalton as revealed by SDS PAGE. The purity was (90 59?0 85)%, which was in parallel with the result tested by HPLC. Conclusion SDS PAGE is accurate, reliable and simple for the determination of melittin.

Objective To assess the aorta elastic properties in the procession of atherosclerosis by ultra‐high frequency ultrasound ,and to detect the relationship between the aorta elastic properties and the atherosclerotic plaque burden .Methods Mice deficient for the apolipoprotein E (ApoE‐/‐) with high‐cholestrol diet were studied as an age‐dependent model of atherosclerosis .At 8 ,16 ,24 and 32 weeks of age , the blood pressure in the ascending aorta was measured by catheter ,and the aorta mechanical properties were assessed by measuring aortic elastic modulus of the ascending aorta with ultra‐high frequency ultrasound .The plaque burden was assessed by high‐frequency ultrasound and Masson′s trichrome stain , separately .Results Vessel thickness at the lesion‐prone sites of the lesser curvature of the aorta and the proximal brachiocephalic artery increased with age ,consistent with the Masson′s trichrome staining which showed age‐dependent worsening of atherosclerosis in the mice model .Elastic modulus of the aorta significantly increased from 8 to 32 weeks of age in E‐/‐mice .There was a statistically difference between any two groups .Conclusions With the progression of atherosclerosis and the increased plaque burden ,aorta mechanical properties deteriorated in Apo E‐/‐mice .Ultra‐high frequency ultrasound was a potential tool for assessment of plaque burden and aorta mechanical properties in mouse model .

OBJECTIVE: To compare the acute toxicity of common injection and sustained-release preparation of norcantharidin for mice so as to identify the attenuation of the sustained-release preparation of norcantharidin. METHODS: The poloxamer 407 was used as a sustained-release vehicle for topical administration of norcantharidin, and the acute toxicity of mice treated with common injection and sustained-release preparation of norcantharidin was observed. The median lethal dose (LD(50)) was calculated by Bliss software. RESULTS: The symptoms of mice were similar between the two groups, but the appearance of symptoms in norcantharidin/poloxamer 407 group was 4 hours later than that in norcantharidin group. The LD(50) of norcantharidin administered through vein injection was 12.6 mg/kg. The LD(50) of norcantharidin/poloxamer 407 administered through intraperitoneal injection, intrahepatic injection and intramuscular injection were 19.9, 19.1 and 20.9 mg/kg, respectively, and the LD(50) of the common preparation were 13.0, 13.1 and 15.1 mg/kg, respectively. CONCLUSION: The norcantharidin/poloxamer 407 is less toxic than the equivalent dose of norcantharidin, mainly because norcantharidin/poloxamer 407 may release norcantharidin sustainedly, thus reducing norcantharidin concentration in blood.

Objective To research and develop a new type of temperature recorder system of vehicle-mounted blood bank which is used in the field training and combat. Methods Based on ATmega48 SCM as control core, the components including digital temperature recorder, LCD, buzzer and so on are used. Results The recorder can not only monitor temperature and display real-time, but also store the data in the recorder of the serial EEPROM (CAT24C64). Additionally, when the temperature exceeds the given range, it can be automatic alarm. Conclusion The temperature recorder with a short collection cycle, the record for a long time and high sensitivity, cost-effective, small size and easy to carry, etc., can be widely used in medicine, food, chemicals, electronic manufacturing, warehousing, logistics, as well as agriculture and other sectors.

Objective To study the reversal effect on acquired multidrug resistance (MDR) of human hepatocellular caricinoma (HCC) by Ganli Injection. Methods Proliferative inhibition rate of HCC BEL-7402/5-Fu cell line and reversal index of 5-Fu acquired MDR were measured by MTT assay. Cell morphological changes were observed under inverted microscope and Wright-Giemsa stain method. Fluorescence intensity of Adriamycin (ADM) was detected by Flow cytometry. Results HCC BEL-7402/5-Fu cell line exhibited cross-resistance to general chemotherapeutics in clinic. Proliferative inhibition rates of HCC BEL-7402/5-Fu cell line treated for 72 h by Ganli Injection at the (matrine) concentration of 0.230, 0.115, 0.058 mg/mL were (9.25?2.38)%, (8.46?1.90)%, and (4.23?2.05)%, respectively. The corresponding reversal indexes to 5-Fu were 5.50, 3.83, and 2.25. Pre-treatment of Galli Injection at the concentration of 0.230 mg/mL for 2 h could increase the accumulation of ADM in cells to 38.61%.Conclusion Ganli Injection has the effect on reversing 5-Fu acquired MDR of human hepatocellular carcinoma in vitro.